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GB201112922D0 - Micro-organ - Google Patents

Micro-organ

Info

Publication number
GB201112922D0
GB201112922D0 GBGB1112922.8A GB201112922A GB201112922D0 GB 201112922 D0 GB201112922 D0 GB 201112922D0 GB 201112922 A GB201112922 A GB 201112922A GB 201112922 D0 GB201112922 D0 GB 201112922D0
Authority
GB
United Kingdom
Prior art keywords
organ
micro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1112922.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Durham
Original Assignee
University of Durham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Durham filed Critical University of Durham
Priority to GBGB1112922.8A priority Critical patent/GB201112922D0/en
Publication of GB201112922D0 publication Critical patent/GB201112922D0/en
Priority to PCT/GB2012/051759 priority patent/WO2013014435A1/en
Priority to US14/235,257 priority patent/US20140154326A1/en
Priority to EP12740650.2A priority patent/EP2737055B1/en
Priority to US15/358,399 priority patent/US20170073646A1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698Skin equivalents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/09Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/092Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells hair cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/09Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323Adult fibroblasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • C12N2503/04Screening or testing on artificial tissues
    • C12N2503/06Screening or testing on artificial skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/003D culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GBGB1112922.8A 2011-07-27 2011-07-27 Micro-organ Ceased GB201112922D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GBGB1112922.8A GB201112922D0 (en) 2011-07-27 2011-07-27 Micro-organ
PCT/GB2012/051759 WO2013014435A1 (en) 2011-07-27 2012-07-23 Micro organ comprising mesenchymal and epithelial cells
US14/235,257 US20140154326A1 (en) 2011-07-27 2012-07-23 Micro organ comprising mesenchymal and epithelial cells
EP12740650.2A EP2737055B1 (en) 2011-07-27 2012-07-23 Micro organ comprising mesenchymal and epithelial cells
US15/358,399 US20170073646A1 (en) 2011-07-27 2016-11-22 Micro organ comprising mesenchymal and epithelial cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1112922.8A GB201112922D0 (en) 2011-07-27 2011-07-27 Micro-organ

Publications (1)

Publication Number Publication Date
GB201112922D0 true GB201112922D0 (en) 2011-09-14

Family

ID=44676260

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1112922.8A Ceased GB201112922D0 (en) 2011-07-27 2011-07-27 Micro-organ

Country Status (4)

Country Link
US (2) US20140154326A1 (en)
EP (1) EP2737055B1 (en)
GB (1) GB201112922D0 (en)
WO (1) WO2013014435A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201303485D0 (en) 2013-02-27 2013-04-10 Alcyomics Ltd Skin model
WO2014179559A1 (en) * 2013-05-03 2014-11-06 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Skin substitutes and methods for hair follicle neogenesis
FR3016373B1 (en) * 2014-01-10 2018-01-19 Laboratoires Expanscience MAMMELON SKIN MODEL RECONSTITUTES
WO2019092667A1 (en) * 2017-11-10 2019-05-16 Vitroscreen S.R.L. Method for preparing three-dimensional scaffold-free microtissues for use in the preclinical screening of active substances
CN109897816A (en) * 2019-03-08 2019-06-18 广西医科大学第一附属医院 A kind of construction method of hair follicle EMIs microenvironment model
US20240240143A1 (en) * 2021-05-27 2024-07-18 The University Of Hong Kong Bioengineered dermal papilla and hair follicles and related products, methods and applications
CN116004513A (en) * 2023-01-12 2023-04-25 泛领生物医学技术(苏州)有限公司 Construction method of skin organ with bracket-free 3D cell sphere structure
WO2024216195A2 (en) * 2023-04-14 2024-10-17 The Johns Hopkins University Multi-compartment organoid systems and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2080693C (en) 1990-04-24 2001-11-27 Mark Eisenberg Composite living skin equivalents
CA2119064A1 (en) 1993-03-17 1994-09-18 Richard A. Berg Dermal-epidermal in vitro test system
BR9915476A (en) * 1998-11-19 2002-01-02 Organogenesis Inc Fabric constructs made by bioengineering and methods for their production and use
WO2003041568A2 (en) 2001-11-15 2003-05-22 University Of Medicine & Dentistry Of New Jersey A three-dimensional matrix for producing living tissue equivalents
WO2003055990A2 (en) * 2001-12-21 2003-07-10 Pharmagap Inc. Method for culturing and expansion of mammalian undifferentiated epidermal keratinocytes exhibiting stem cell characteristics
DE102005028899B4 (en) * 2005-06-17 2007-09-20 Gkss-Forschungszentrum Geesthacht Gmbh Skin equivalent and method for producing the same
JP5386180B2 (en) * 2006-02-28 2014-01-15 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク Method for compact aggregation of dermal cells
ES2419232T3 (en) * 2006-06-27 2013-08-20 Shiseido Company, Limited Aggregate of cells comprising various kinds of soma-derived cells capable of forming a structure of the primitive organ type

Also Published As

Publication number Publication date
US20170073646A1 (en) 2017-03-16
EP2737055A1 (en) 2014-06-04
US20140154326A1 (en) 2014-06-05
EP2737055B1 (en) 2020-11-11
WO2013014435A1 (en) 2013-01-31

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)