[go: up one dir, main page]

GB201114909D0 - Biomarkers for lysosomal storage disorders - Google Patents

Biomarkers for lysosomal storage disorders

Info

Publication number
GB201114909D0
GB201114909D0 GB201114909A GB201114909A GB201114909D0 GB 201114909 D0 GB201114909 D0 GB 201114909D0 GB 201114909 A GB201114909 A GB 201114909A GB 201114909 A GB201114909 A GB 201114909A GB 201114909 D0 GB201114909 D0 GB 201114909D0
Authority
GB
United Kingdom
Prior art keywords
sample
lysosomal storage
biomarkers
storage disorders
metallothionein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GB201114909A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fondazione Telethon
Ospedale San Raffaele SRL
Brigham and Womens Hospital Inc
Original Assignee
SAN RAFFAELE CENTRO FOND
Fondazione Telethon
Ospedale San Raffaele SRL
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SAN RAFFAELE CENTRO FOND, Fondazione Telethon, Ospedale San Raffaele SRL, Brigham and Womens Hospital Inc filed Critical SAN RAFFAELE CENTRO FOND
Priority to GB201114909A priority Critical patent/GB201114909D0/en
Publication of GB201114909D0 publication Critical patent/GB201114909D0/en
Priority to PCT/IB2012/054469 priority patent/WO2013030785A1/en
Ceased legal-status Critical Current

Links

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)

Abstract

A method of diagnosis or prognosis of a lysosomal storage disorder in a subject, wherein said method comprises (i) providing a sample from said subject, (ii) determining the expression level of a metallothionein in said sample, (iii) comparing the expression level of the metallothionein in said sample with the expression level of the metallothionein in a sample from healthy subjects or in a previous sample from the same subject.
GB201114909A 2011-08-30 2011-08-30 Biomarkers for lysosomal storage disorders Ceased GB201114909D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB201114909A GB201114909D0 (en) 2011-08-30 2011-08-30 Biomarkers for lysosomal storage disorders
PCT/IB2012/054469 WO2013030785A1 (en) 2011-08-30 2012-08-30 Biomarkers for lysosomal storage disorders

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB201114909A GB201114909D0 (en) 2011-08-30 2011-08-30 Biomarkers for lysosomal storage disorders

Publications (1)

Publication Number Publication Date
GB201114909D0 true GB201114909D0 (en) 2011-10-12

Family

ID=44838884

Family Applications (1)

Application Number Title Priority Date Filing Date
GB201114909A Ceased GB201114909D0 (en) 2011-08-30 2011-08-30 Biomarkers for lysosomal storage disorders

Country Status (2)

Country Link
GB (1) GB201114909D0 (en)
WO (1) WO2013030785A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3526319B1 (en) 2016-10-14 2025-12-10 Children's Medical Center Corporation Compositions and methods for treating diseases and disorders of the central nervous system
US12000843B2 (en) 2017-01-17 2024-06-04 Children's Medical Center Corporation Compositions and methods for diagnosing and treating peroxisomal diseases
US11548936B2 (en) 2017-01-17 2023-01-10 Children's Medical Center Corporation Compositions and methods for treating lysosomal storage diseases and disorders
WO2020123511A2 (en) * 2018-12-10 2020-06-18 Denali Therapeutics Inc. Lysosomal storage disorder biomarkers and methods of use thereof
CN113265461B (en) * 2021-07-02 2022-05-13 北京华诺奥美医学检验实验室有限公司 Primer group, probe group and kit for detecting high-frequency gene pathogenic variation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN991796A0 (en) * 1996-05-17 1996-06-13 Women's And Children's Hospital Early detection of lysosomal storage disorders
US7378231B1 (en) * 1999-03-17 2008-05-27 Women's And Children's Hospital Diagnosis of lysosomal storage disorders using saposins and other markers
ATE550664T1 (en) * 2003-03-31 2012-04-15 Womens & Childrens Hospital MULTIPLEX SCREENING FOR LYSOSOMAL STORAGE DISEASES (LSDS)
WO2007136782A2 (en) * 2006-05-19 2007-11-29 Historx, Inc. Kits and methods for evaluating misfolded proteins
WO2011028941A2 (en) * 2009-09-04 2011-03-10 The United States Of America, As Represented By The Secretary Department Of Health & Human Services Disabling autophagy as a treatment for lysosomal storage diseases

Also Published As

Publication number Publication date
WO2013030785A1 (en) 2013-03-07

Similar Documents

Publication Publication Date Title
MX2013003077A (en) BREAST CANCER DIAGNOSIS.
WO2014028884A3 (en) Cancer diagnostics using biomarkers
PH12013502340A1 (en) Biomarkers for hedgehog inhibitor therapy
BR112014031365A2 (en) methods of detecting disease or conditions
EA201390149A1 (en) METHODS FOR DETECTING DISEASES OR PATHOLOGICAL CONDITIONS USING PHAGOCYTARY CELLS
MX367046B (en) Pathway specific markers for diagnosing irritable bowel syndrome.
BR112012030587A2 (en) methods for diagnosing pancreatic cancer, to identify whether or not an individual needs pancreatic cancer therapy, and to determine if pancreatic cancer therapy succeeds, a device for diagnosing pancreatic cancer, and using at least one biomarker.
MX355416B (en) Lung cancer biomarkers and uses thereof.
GB201120552D0 (en) Method and system for integrated analysis
MX365061B (en) Biomarkers related to kidney function and methods using the same.
WO2013107459A3 (en) Microrna for diagnosis of pancreatic cancer and/or prognosis of patients with pancreatic cancer by blood samples
IN2013CN01129A (en)
EP4060048A3 (en) Non-invasive diagnostic method for diagnosing bladder cancer
WO2013066369A3 (en) Methods for detecting graft-versus-host disease
WO2013163568A3 (en) Methods for evaluating lung cancer status
NZ629555A (en) Monocyte biomarkers for cancer detection
EA201500080A1 (en) METHOD IN VITRO DIAGNOSIS AND MONITORING OF CANCER
WO2013049152A3 (en) Methods for evaluating lung cancer status
SA112330754B1 (en) Diagnostic method for detection of cardiovascular disease
MX381530B (en) Method for the diagnosis of niemann-pick disease
WO2014187884A3 (en) Mirnas as non-invasive biomarkers for heart failure
GB201114909D0 (en) Biomarkers for lysosomal storage disorders
MX2016002529A (en) Risk markers for cardiovascular disease in patients with chronic kidney disease.
WO2012145399A3 (en) Methods of diagnosing cancer in a patient
WO2013050950A3 (en) Method for monitoring, diagnosis and/or prognosis of hypoxia related disorders using nfat5

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)
COOA Change in applicant's name or ownership of the application

Free format text: FORMER OWNERS: FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR;FONDAZIONE TELETHON;THE BRIGHAM AND WOMEN S HOSPITAL,, INC.

Owner name: FONDAZIONE TELETHON

Free format text: FORMER OWNERS: FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR;FONDAZIONE TELETHON;THE BRIGHAM AND WOMEN S HOSPITAL,, INC.

Owner name: THE BRIGHAM AND WOMEN S HOSPITAL,, INC.

Free format text: FORMER OWNERS: FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR;FONDAZIONE TELETHON;THE BRIGHAM AND WOMEN S HOSPITAL,, INC.

Owner name: OSPEDALE SAN RAFFAELE S.R.L.