GB2005259B - Hexahydropyrrolo indole derivatives - Google Patents
Hexahydropyrrolo indole derivativesInfo
- Publication number
- GB2005259B GB2005259B GB7837048A GB7837048A GB2005259B GB 2005259 B GB2005259 B GB 2005259B GB 7837048 A GB7837048 A GB 7837048A GB 7837048 A GB7837048 A GB 7837048A GB 2005259 B GB2005259 B GB 2005259B
- Authority
- GB
- United Kingdom
- Prior art keywords
- hexahydropyrrolo
- indole derivatives
- indole
- derivatives
- hexahydropyrrolo indole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BZFDCAZUWRDJQX-UHFFFAOYSA-N C1CC2=NC=CC2=C2NCCC21 Chemical class C1CC2=NC=CC2=C2NCCC21 BZFDCAZUWRDJQX-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT09574/77A IT1109003B (en) | 1977-09-20 | 1977-09-20 | DERIVATIVES OF 1 2 3 8 3 A 8 A ESAI DROPIRROLO 23 B INDOLO |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2005259A GB2005259A (en) | 1979-04-19 |
| GB2005259B true GB2005259B (en) | 1982-06-23 |
Family
ID=11132370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7837048A Expired GB2005259B (en) | 1977-09-20 | 1978-09-15 | Hexahydropyrrolo indole derivatives |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS54112897A (en) |
| AR (1) | AR222311A1 (en) |
| CA (1) | CA1125657A (en) |
| DE (1) | DE2839279A1 (en) |
| FR (1) | FR2434167A1 (en) |
| GB (1) | GB2005259B (en) |
| IT (1) | IT1109003B (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1199076B (en) * | 1984-03-01 | 1988-12-30 | Consiglio Nazionale Ricerche | PHYSOSTIGMINE DERIVATIVES WITH PROPERTY OF INHIBITION OF ACETICOLINESTERASI AND RELATED PRODUCTION PROCESS |
| GB8616089D0 (en) * | 1986-07-02 | 1986-08-06 | Univ Manchester | Organic compounds |
| US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| IT1225462B (en) * | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | ORGANIC SALTS OF PHYSOSTIGMIN DERIVATIVES |
| AT400331B (en) * | 1987-05-15 | 1995-12-27 | Hoechst Roussel Pharma | 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo(2,3- b)indoles, a process for their preparation and their use as pharmaceuticals |
| US4971992A (en) * | 1989-03-27 | 1990-11-20 | Hoechst-Roussel Pharmaceuticals Inc. | Carbonate derivatives of eseroline |
| US4914102A (en) * | 1989-09-28 | 1990-04-03 | Hoechst Roussel Pharmaceuticals, Inc. | N-aminocarbamates related to physostigmine, pharmacentical compositions and use |
| US5260452A (en) * | 1989-11-03 | 1993-11-09 | Hoechst-Roussel Pharmaceuticals Inc. | 4- and 6-carbamates related to physostigmine and intermediates for the preparation thereof |
| US5206260A (en) * | 1991-11-07 | 1993-04-27 | Merck & Co., Inc. | Hexahydropyrrolo[2,3-b]indole derivatives |
| GB9205670D0 (en) * | 1992-03-16 | 1992-04-29 | Indena Spa | New derivatives of physostigmine,their use and pharmaceutical formulations containing them |
| CA2274658A1 (en) * | 1997-10-10 | 1999-04-22 | Roberto Pighi | A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity |
| US6495700B1 (en) * | 2002-01-09 | 2002-12-17 | Axonyx, Inc. | Process for producing phenserine and its analog |
-
1977
- 1977-09-20 IT IT09574/77A patent/IT1109003B/en active
-
1978
- 1978-09-07 AR AR273611A patent/AR222311A1/en active
- 1978-09-09 DE DE19782839279 patent/DE2839279A1/en not_active Withdrawn
- 1978-09-15 GB GB7837048A patent/GB2005259B/en not_active Expired
- 1978-09-19 CA CA311,555A patent/CA1125657A/en not_active Expired
- 1978-09-20 JP JP11470178A patent/JPS54112897A/en active Pending
- 1978-09-20 FR FR7826975A patent/FR2434167A1/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IT1109003B (en) | 1985-12-16 |
| FR2434167B1 (en) | 1983-03-18 |
| GB2005259A (en) | 1979-04-19 |
| JPS54112897A (en) | 1979-09-04 |
| DE2839279A1 (en) | 1979-03-29 |
| FR2434167A1 (en) | 1980-03-21 |
| CA1125657A (en) | 1982-06-15 |
| AR222311A1 (en) | 1981-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |