GB2004744A - Immunological preparations containing major histocompatibility complex antigen - Google Patents
Immunological preparations containing major histocompatibility complex antigenInfo
- Publication number
- GB2004744A GB2004744A GB7838177A GB7838177A GB2004744A GB 2004744 A GB2004744 A GB 2004744A GB 7838177 A GB7838177 A GB 7838177A GB 7838177 A GB7838177 A GB 7838177A GB 2004744 A GB2004744 A GB 2004744A
- Authority
- GB
- United Kingdom
- Prior art keywords
- major histocompatibility
- histocompatibility complex
- preparations containing
- antigen
- complex antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108700018351 Major Histocompatibility Complex Proteins 0.000 title abstract 4
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 title abstract 4
- 239000000427 antigen Substances 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000001900 immune effect Effects 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 102100031547 HLA class II histocompatibility antigen, DO alpha chain Human genes 0.000 abstract 1
- 101000866278 Homo sapiens HLA class II histocompatibility antigen, DO alpha chain Proteins 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000007822 coupling agent Substances 0.000 abstract 1
- 230000002538 fungal effect Effects 0.000 abstract 1
- 239000000813 peptide hormone Substances 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/605—MHC molecules or ligands thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
An immunologically active preparation for human or veterinary use comprises an antigenic material in combination with an MHC (Major Histocompatibility Complex) antigen, especially Human Lymphocyte Antigen (HLA). The MHC may be papain- solubilized, and the antigenic material may be a bacterial, viral, protozoal or fungal antigen, a toxoid or toxin, a peptide hormone or a hapten. The combination is brought about with a conventional coupling agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7838177A GB2004744B (en) | 1977-09-28 | 1978-09-26 | Immonulogical preparations |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4033977 | 1977-09-28 | ||
| GB7838177A GB2004744B (en) | 1977-09-28 | 1978-09-26 | Immonulogical preparations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2004744A true GB2004744A (en) | 1979-04-11 |
| GB2004744B GB2004744B (en) | 1982-05-26 |
Family
ID=26264373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7838177A Expired GB2004744B (en) | 1977-09-28 | 1978-09-26 | Immonulogical preparations |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2004744B (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1980001986A1 (en) * | 1979-03-27 | 1980-10-02 | A Sanderson | Improvements in or relating to immunological preparations |
| EP0267204A4 (en) * | 1986-04-21 | 1989-03-22 | Bioentpr Pty Ltd | Immunopotentiation. |
| EP0309299A1 (en) * | 1987-09-24 | 1989-03-29 | Cambridge Life Sciences Plc | Method for the production of antigenic protein-hapten conjugates, and antibodies corresponding thereto |
| EP0474764A4 (en) * | 1989-05-31 | 1992-11-19 | Scripps Clinic And Research Foundation | Method to treat rheumatoid arthritis |
| US5807559A (en) * | 1992-04-28 | 1998-09-15 | Astra Aktiebolag | Compositions for generating T cell immunity against carbohydrate structures |
| US5976839A (en) * | 1987-03-13 | 1999-11-02 | Bioenterprises Pty Limited | Immunopotentiation through covalent linkage between immunogen and immunopotentiating molecules |
-
1978
- 1978-09-26 GB GB7838177A patent/GB2004744B/en not_active Expired
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1980001986A1 (en) * | 1979-03-27 | 1980-10-02 | A Sanderson | Improvements in or relating to immunological preparations |
| EP0267204A4 (en) * | 1986-04-21 | 1989-03-22 | Bioentpr Pty Ltd | Immunopotentiation. |
| US5874083A (en) * | 1986-04-21 | 1999-02-23 | Bioenterprises Pty Limited | Immunopotentiating complexes comprising TraT proteins |
| US5976839A (en) * | 1987-03-13 | 1999-11-02 | Bioenterprises Pty Limited | Immunopotentiation through covalent linkage between immunogen and immunopotentiating molecules |
| EP0309299A1 (en) * | 1987-09-24 | 1989-03-29 | Cambridge Life Sciences Plc | Method for the production of antigenic protein-hapten conjugates, and antibodies corresponding thereto |
| WO1989003040A1 (en) * | 1987-09-24 | 1989-04-06 | Cambridge Life Sciences Plc | Method for the production of antigenic protein-hapten conjugates, and antibodies corresponding thereto |
| EP0474764A4 (en) * | 1989-05-31 | 1992-11-19 | Scripps Clinic And Research Foundation | Method to treat rheumatoid arthritis |
| US5807559A (en) * | 1992-04-28 | 1998-09-15 | Astra Aktiebolag | Compositions for generating T cell immunity against carbohydrate structures |
| US6033669A (en) * | 1992-04-28 | 2000-03-07 | Astra Aktiebolag | Methods for generating cytotoxic T cells and treatment of diseases thereby |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2004744B (en) | 1982-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |