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GB2001624B - Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them - Google Patents

Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them

Info

Publication number
GB2001624B
GB2001624B GB7827634A GB7827634A GB2001624B GB 2001624 B GB2001624 B GB 2001624B GB 7827634 A GB7827634 A GB 7827634A GB 7827634 A GB7827634 A GB 7827634A GB 2001624 B GB2001624 B GB 2001624B
Authority
GB
United Kingdom
Prior art keywords
manufacture
pharmaceutical compositions
compositions containing
guanidine derivatives
derivatives processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7827634A
Other versions
GB2001624A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Zeneca Inc
Original Assignee
Imperial Chemical Industries Ltd
ICI Americas Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd, ICI Americas Inc filed Critical Imperial Chemical Industries Ltd
Priority to GB7827634A priority Critical patent/GB2001624B/en
Publication of GB2001624A publication Critical patent/GB2001624A/en
Application granted granted Critical
Publication of GB2001624B publication Critical patent/GB2001624B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB7827634A 1977-04-20 1978-06-22 Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them Expired GB2001624B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7827634A GB2001624B (en) 1977-04-20 1978-06-22 Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1638977 1977-04-20
GB7827634A GB2001624B (en) 1977-04-20 1978-06-22 Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
GB2001624A GB2001624A (en) 1979-02-07
GB2001624B true GB2001624B (en) 1982-03-03

Family

ID=26252012

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7827634A Expired GB2001624B (en) 1977-04-20 1978-06-22 Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them

Country Status (1)

Country Link
GB (1) GB2001624B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390701A (en) 1981-05-18 1983-06-28 Bristol-Myers Company 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione
US4395553A (en) 1981-05-18 1983-07-26 Bristol-Myers Company Chemical compounds

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374836A (en) * 1978-10-16 1983-02-22 Imperial Chemical Industries Ltd. Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them
IL61233A (en) * 1979-10-24 1984-08-31 Smith Kline French Lab Guanidino thiazolylalkylamino(alkylthioalkylamino)nitro pyrroles,process for their preparation and pharmaceutical compositions containing them
IL61234A (en) * 1979-10-24 1984-03-30 Smith Kline French Lab Guanidino thiazolyl alkylamino(alkylthioalkylamino)nitrotetrahydropyridines,process for preparing them and pharmaceutical compositions containing them
GR71929B (en) * 1979-11-13 1983-08-19 Ici Ltd
US4394508A (en) * 1980-06-07 1983-07-19 Bristol-Myers Company Chemical compounds
EP0045155B1 (en) * 1980-07-30 1985-01-02 Imperial Chemical Industries Plc Guanidine derivatives
US4460584A (en) * 1981-03-13 1984-07-17 Imperial Chemical Industries Plc Nitrogen heterocycles
IN158869B (en) * 1981-03-18 1987-02-07 Ici Plc
EP0065823A1 (en) * 1981-05-13 1982-12-01 Imperial Chemical Industries Plc Heterocyclic guanidines as histamine H-2 antagonists
US4546188A (en) * 1981-05-18 1985-10-08 Bristol-Myers Company Substituted 1,2-diaminocyclobutene-3,4-diones
US4539316A (en) * 1981-05-18 1985-09-03 Bristol-Myers Company Pyridine derivatives of 1,2-diaminocyclobutene-3,4-diones
EP0102026A3 (en) * 1982-08-20 1984-05-16 Hoechst Uk Limited Thiazole derivatives
JPS59104370A (en) * 1982-12-03 1984-06-16 Kotobuki Seiyaku Kk Thiazole derivative and its production
EP0156286A3 (en) * 1984-03-27 1986-08-20 Hoechst Uk Limited Thiatrizine derivatives
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390701A (en) 1981-05-18 1983-06-28 Bristol-Myers Company 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione
US4395553A (en) 1981-05-18 1983-07-26 Bristol-Myers Company Chemical compounds

Also Published As

Publication number Publication date
GB2001624A (en) 1979-02-07

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940622