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GB2001307A - Sulphonamide blood complement inhibitors - Google Patents

Sulphonamide blood complement inhibitors

Info

Publication number
GB2001307A
GB2001307A GB787827720A GB7827720A GB2001307A GB 2001307 A GB2001307 A GB 2001307A GB 787827720 A GB787827720 A GB 787827720A GB 7827720 A GB7827720 A GB 7827720A GB 2001307 A GB2001307 A GB 2001307A
Authority
GB
United Kingdom
Prior art keywords
sulphonamide
complement inhibitors
blood complement
image
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB787827720A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/812,013 external-priority patent/US4122088A/en
Priority claimed from US05/812,014 external-priority patent/US4119784A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of GB2001307A publication Critical patent/GB2001307A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/36—Seven-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The compounds have the formula: <IMAGE> wherein R is alkali metal; R1 and R2 are each <IMAGE> or when taken together, R1 and R2 may be <IMAGE> Chemically similar intermediate compounds are also disclosed.
GB787827720A 1977-07-01 1978-06-23 Sulphonamide blood complement inhibitors Withdrawn GB2001307A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/812,013 US4122088A (en) 1977-07-01 1977-07-01 Dicarboxyphenyl substituted bis-sulfonylimino dibenzodithiazepine tetroxides
US05/812,014 US4119784A (en) 1977-07-01 1977-07-01 Anionic substituted sulfonamido biphenyls

Publications (1)

Publication Number Publication Date
GB2001307A true GB2001307A (en) 1979-01-31

Family

ID=27123545

Family Applications (1)

Application Number Title Priority Date Filing Date
GB787827720A Withdrawn GB2001307A (en) 1977-07-01 1978-06-23 Sulphonamide blood complement inhibitors

Country Status (5)

Country Link
JP (1) JPS5414948A (en)
DE (1) DE2827932A1 (en)
FR (1) FR2395989A1 (en)
GB (1) GB2001307A (en)
NL (1) NL7807148A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5746968A (en) * 1994-10-20 1998-05-05 Interventional Technologies, Inc. Method for manufacturing a high strength angioplasty balloon

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0705400D0 (en) * 2007-03-21 2007-05-02 Univ Aberdeen Therapeutic compounds andm their use
GB0817208D0 (en) * 2008-09-19 2008-10-29 Pimco 2664 Ltd Therapeutic apsap compounds and their use
DE102009011055A1 (en) * 2009-03-02 2010-09-09 Studiengesellschaft Kohle Mbh Chiral disulfonic acids and disulfonimides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4027038A (en) * 1976-05-10 1977-05-31 American Cyanamid Company Complement inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5746968A (en) * 1994-10-20 1998-05-05 Interventional Technologies, Inc. Method for manufacturing a high strength angioplasty balloon

Also Published As

Publication number Publication date
DE2827932A1 (en) 1979-01-18
FR2395989A1 (en) 1979-01-26
FR2395989B1 (en) 1980-07-18
JPS5414948A (en) 1979-02-03
NL7807148A (en) 1979-01-03

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)