GB2000970A - Injectable chloramphenicol composition - Google Patents
Injectable chloramphenicol compositionInfo
- Publication number
- GB2000970A GB2000970A GB7829921A GB7829921A GB2000970A GB 2000970 A GB2000970 A GB 2000970A GB 7829921 A GB7829921 A GB 7829921A GB 7829921 A GB7829921 A GB 7829921A GB 2000970 A GB2000970 A GB 2000970A
- Authority
- GB
- United Kingdom
- Prior art keywords
- composition
- chloramphenicol
- injectable
- methylpyrrolidone
- miscible
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 title abstract 2
- 229960005091 chloramphenicol Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 abstract 2
- 230000036765 blood level Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
An injectable composition contains chloramphenicol, N-methylpyrrolidone and polyvinyl-pyrrolidone. The composition may also contain a pharmaceutically-acceptable solvent which is miscible with N-methylpyrrolidone. It is used in veterinary medicine and is stable, concentrated, exhibits constant blood levels and does not produce unpleasant side effects.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL52533A IL52533A (en) | 1977-07-15 | 1977-07-15 | Injectable chloramphenicol composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2000970A true GB2000970A (en) | 1979-01-24 |
| GB2000970B GB2000970B (en) | 1982-03-17 |
Family
ID=11049656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7829921A Expired GB2000970B (en) | 1977-07-15 | 1978-07-14 | Injectable chloramphenicol composition |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5420125A (en) |
| AT (1) | AT360149B (en) |
| AU (1) | AU3752578A (en) |
| BE (1) | BE869001A (en) |
| CA (1) | CA1112572A (en) |
| DE (1) | DE2829408A1 (en) |
| FR (1) | FR2397191A1 (en) |
| GB (1) | GB2000970B (en) |
| IE (1) | IE47126B1 (en) |
| IL (1) | IL52533A (en) |
| NL (1) | NL7807641A (en) |
| NZ (1) | NZ187683A (en) |
| ZA (1) | ZA783671B (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0021847A3 (en) * | 1979-07-02 | 1981-08-12 | Pfizer Inc. | Long acting sulfonamide injectable compositions |
| EP0039967A1 (en) * | 1980-05-08 | 1981-11-18 | Gist-Brocades N.V. | Solvate of amoxicillin, process for the preparation thereof and process for the preparation of injectable preparations from this solvate |
| EP0096942A3 (en) * | 1982-06-15 | 1984-02-15 | Aesculaap B.V. | Process for preparing an oxytetracycline composition |
| EP0212853A3 (en) * | 1985-08-21 | 1987-07-29 | Warner-Lambert Company | Parenteral phenytoin compositions |
| FR2603803A1 (en) * | 1986-09-15 | 1988-03-18 | Zambon Spa | PHARMACEUTICAL PREPARATION FOR VETERINARY USE CONTAINING THIAMPHENICOL |
| WO2006067138A3 (en) * | 2004-12-21 | 2006-09-21 | Intervet Int Bv | Injectable veterinary composition |
| EP1439828A4 (en) * | 2001-10-02 | 2007-10-03 | Ivx Animal Health Inc | Veterinaire florfenicol formulation that is syringeable under cold weather conditions |
| CN113694018A (en) * | 2021-09-08 | 2021-11-26 | 海南制药厂有限公司制药二厂 | Chloramphenicol injection and preparation method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6031189A (en) * | 1983-07-30 | 1985-02-16 | カシオ計算機株式会社 | musical tone generator |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1538903A (en) * | 1975-04-11 | 1979-01-24 | Nelson Res & Dev | Carrier for a topically applied physiologically active agent or cosmetic agent |
-
1977
- 1977-07-15 IL IL52533A patent/IL52533A/en unknown
-
1978
- 1978-06-27 ZA ZA00783671A patent/ZA783671B/en unknown
- 1978-06-27 NZ NZ187683A patent/NZ187683A/en unknown
- 1978-06-28 AU AU37525/78A patent/AU3752578A/en active Pending
- 1978-07-04 FR FR7819873A patent/FR2397191A1/en active Granted
- 1978-07-05 DE DE19782829408 patent/DE2829408A1/en not_active Withdrawn
- 1978-07-14 BE BE189287A patent/BE869001A/en unknown
- 1978-07-14 IE IE1425/78A patent/IE47126B1/en unknown
- 1978-07-14 CA CA307,371A patent/CA1112572A/en not_active Expired
- 1978-07-14 AT AT511878A patent/AT360149B/en not_active IP Right Cessation
- 1978-07-14 JP JP8665578A patent/JPS5420125A/en active Pending
- 1978-07-14 GB GB7829921A patent/GB2000970B/en not_active Expired
- 1978-07-17 NL NL7807641A patent/NL7807641A/en not_active Application Discontinuation
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0021847A3 (en) * | 1979-07-02 | 1981-08-12 | Pfizer Inc. | Long acting sulfonamide injectable compositions |
| EP0039967A1 (en) * | 1980-05-08 | 1981-11-18 | Gist-Brocades N.V. | Solvate of amoxicillin, process for the preparation thereof and process for the preparation of injectable preparations from this solvate |
| EP0096942A3 (en) * | 1982-06-15 | 1984-02-15 | Aesculaap B.V. | Process for preparing an oxytetracycline composition |
| EP0212853A3 (en) * | 1985-08-21 | 1987-07-29 | Warner-Lambert Company | Parenteral phenytoin compositions |
| AU581319B2 (en) * | 1985-08-21 | 1989-02-16 | Warner-Lambert Company | Parenteral phenytoin compositions |
| FR2603803A1 (en) * | 1986-09-15 | 1988-03-18 | Zambon Spa | PHARMACEUTICAL PREPARATION FOR VETERINARY USE CONTAINING THIAMPHENICOL |
| BE1000189A3 (en) * | 1986-09-15 | 1988-07-26 | Zambon Spa | Pharmaceutical preparation for animal treatment. |
| US4912138A (en) * | 1986-09-15 | 1990-03-27 | Zambon S.P.A. | Pharmaceutical preparation containing thiamphenicol for veterinary use |
| EP1439828A4 (en) * | 2001-10-02 | 2007-10-03 | Ivx Animal Health Inc | Veterinaire florfenicol formulation that is syringeable under cold weather conditions |
| WO2006067138A3 (en) * | 2004-12-21 | 2006-09-21 | Intervet Int Bv | Injectable veterinary composition |
| US8680154B2 (en) | 2004-12-21 | 2014-03-25 | Intervet International B.V. | Injectable veterinary composition |
| CN113694018A (en) * | 2021-09-08 | 2021-11-26 | 海南制药厂有限公司制药二厂 | Chloramphenicol injection and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA783671B (en) | 1979-06-27 |
| FR2397191A1 (en) | 1979-02-09 |
| ATA511878A (en) | 1980-05-15 |
| JPS5420125A (en) | 1979-02-15 |
| AT360149B (en) | 1980-12-29 |
| FR2397191B1 (en) | 1981-12-31 |
| IE47126B1 (en) | 1983-12-28 |
| IL52533A0 (en) | 1977-10-31 |
| CA1112572A (en) | 1981-11-17 |
| AU3752578A (en) | 1980-01-03 |
| IE781425L (en) | 1979-01-15 |
| NZ187683A (en) | 1981-03-16 |
| DE2829408A1 (en) | 1979-02-01 |
| GB2000970B (en) | 1982-03-17 |
| IL52533A (en) | 1980-01-31 |
| NL7807641A (en) | 1979-01-17 |
| BE869001A (en) | 1979-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |