GB2093032B - Novel condurango glycosides process for their preparation antineoplastic agent and composition containing same - Google Patents
Novel condurango glycosides process for their preparation antineoplastic agent and composition containing sameInfo
- Publication number
- GB2093032B GB2093032B GB8209580A GB8209580A GB2093032B GB 2093032 B GB2093032 B GB 2093032B GB 8209580 A GB8209580 A GB 8209580A GB 8209580 A GB8209580 A GB 8209580A GB 2093032 B GB2093032 B GB 2093032B
- Authority
- GB
- United Kingdom
- Prior art keywords
- condurango
- novel
- composition containing
- antineoplastic agent
- containing same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940034982 antineoplastic agent Drugs 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229930192357 condurangoglycoside Natural products 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2769780A JPS56123999A (en) | 1980-03-05 | 1980-03-05 | Cundurango glycoside, its preparation and antitumor agent comprising it |
| JP7359480A JPS56169700A (en) | 1980-05-31 | 1980-05-31 | Condurango glucoside b0, its preparation and antitumor agent consisting of the same |
| JP9354480A JPS5718700A (en) | 1980-07-09 | 1980-07-09 | 20-o-methyl-condurango glycoside do, its preparation, and antitumor agent comprising it |
| JP12517580A JPS5748998A (en) | 1980-09-09 | 1980-09-09 | Novel condurango glycoside, its preparation and antitumor agent containing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2093032A GB2093032A (en) | 1982-08-25 |
| GB2093032B true GB2093032B (en) | 1984-02-01 |
Family
ID=27458742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8209580A Expired GB2093032B (en) | 1980-03-05 | 1981-03-05 | Novel condurango glycosides process for their preparation antineoplastic agent and composition containing same |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4452786A (en) |
| EP (1) | EP0054570A4 (en) |
| AU (1) | AU6780081A (en) |
| BE (1) | BE887793A (en) |
| CA (1) | CA1169852A (en) |
| CH (1) | CH647533A5 (en) |
| GB (1) | GB2093032B (en) |
| IT (1) | IT1144136B (en) |
| SE (1) | SE8202140L (en) |
| WO (1) | WO1981002577A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3031745A1 (en) * | 1979-08-23 | 1981-05-27 | Zenyaku Kogyo Kk | MARSDENIA CUNDURANGO REICHENBACH FIL EXTRACTS, METHOD FOR THE PRODUCTION THEREOF, ANTITUARY AND MEDICINAL PRODUCTS CONTAINING THESE EXTRACTS, AND APPLICATION OF THE EXTRACTS FOR THE TREATMENT OF TUMORS |
| CN1131237C (en) | 1997-09-26 | 2003-12-17 | 中国人民解放军军事医学科学院放射医学研究所 | Use of steroidal saponins in preventing and treating senile dementia and new steroidal saponins |
| GB9923076D0 (en) | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| US7423008B2 (en) * | 2004-03-01 | 2008-09-09 | University Of Kentucky Research Foundation | Derivatives of mithramycin and methods of making and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2557916A (en) * | 1948-07-31 | 1951-06-19 | Wyeth Corp | Preparation of a cardio-active glycoside |
| US2780620A (en) * | 1954-01-28 | 1957-02-05 | Merle M Krider | Partial acidic hydrolysis of steroidal saponins |
| US3960839A (en) * | 1973-02-09 | 1976-06-01 | Escuela Politecnica Nacional | Process for recovering and isolating solasodine and glycosides thereof |
| DE2354119A1 (en) * | 1973-10-29 | 1975-05-15 | Boehringer Sohn Ingelheim | NEW ORTHOFORM DERIVATIVES OF DIGITOXIN, THE PROCESS FOR THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINED |
| CH621803A5 (en) * | 1974-08-08 | 1981-02-27 | Siphar Sa | |
| US4084010A (en) * | 1976-01-01 | 1978-04-11 | Tsunematsu Takemoto | Glycosides having sweetness |
| GB1574806A (en) * | 1976-06-03 | 1980-09-10 | Inverni Della Beffa Spa | Production of purified ginseng extracts and pharmaceutical compositions containing the extracts |
-
1981
- 1981-03-03 IT IT8167295A patent/IT1144136B/en active
- 1981-03-04 BE BE0/204013A patent/BE887793A/en not_active IP Right Cessation
- 1981-03-05 US US06/320,974 patent/US4452786A/en not_active Expired - Fee Related
- 1981-03-05 EP EP19810900551 patent/EP0054570A4/en not_active Ceased
- 1981-03-05 WO PCT/JP1981/000045 patent/WO1981002577A1/en not_active Ceased
- 1981-03-05 GB GB8209580A patent/GB2093032B/en not_active Expired
- 1981-03-05 CH CH7326/81A patent/CH647533A5/en not_active IP Right Cessation
- 1981-03-05 AU AU67800/81A patent/AU6780081A/en not_active Abandoned
- 1981-03-05 CA CA000372389A patent/CA1169852A/en not_active Expired
-
1982
- 1982-04-02 SE SE8202140A patent/SE8202140L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1169852A (en) | 1984-06-26 |
| AU6780081A (en) | 1981-09-23 |
| BE887793A (en) | 1981-07-01 |
| IT8167295A0 (en) | 1981-03-03 |
| SE8202140L (en) | 1982-04-02 |
| WO1981002577A1 (en) | 1981-09-17 |
| CH647533A5 (en) | 1985-01-31 |
| EP0054570A4 (en) | 1982-07-13 |
| EP0054570A1 (en) | 1982-06-30 |
| IT1144136B (en) | 1986-10-29 |
| GB2093032A (en) | 1982-08-25 |
| US4452786A (en) | 1984-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19960305 |