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GB2068970B - Recombinant dna technique for the preparation of a protein resembling human interferon - Google Patents

Recombinant dna technique for the preparation of a protein resembling human interferon

Info

Publication number
GB2068970B
GB2068970B GB8102051A GB8102051A GB2068970B GB 2068970 B GB2068970 B GB 2068970B GB 8102051 A GB8102051 A GB 8102051A GB 8102051 A GB8102051 A GB 8102051A GB 2068970 B GB2068970 B GB 2068970B
Authority
GB
United Kingdom
Prior art keywords
preparation
recombinant dna
human interferon
dna technique
resembling human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8102051A
Other versions
GB2068970A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Priority to GB8102051A priority Critical patent/GB2068970B/en
Publication of GB2068970A publication Critical patent/GB2068970A/en
Application granted granted Critical
Publication of GB2068970B publication Critical patent/GB2068970B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
GB8102051A 1980-02-06 1981-01-23 Recombinant dna technique for the preparation of a protein resembling human interferon Expired GB2068970B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB8102051A GB2068970B (en) 1980-02-06 1981-01-23 Recombinant dna technique for the preparation of a protein resembling human interferon

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8003947 1980-02-06
GB8102051A GB2068970B (en) 1980-02-06 1981-01-23 Recombinant dna technique for the preparation of a protein resembling human interferon

Publications (2)

Publication Number Publication Date
GB2068970A GB2068970A (en) 1981-08-19
GB2068970B true GB2068970B (en) 1983-06-22

Family

ID=26274412

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8102051A Expired GB2068970B (en) 1980-02-06 1981-01-23 Recombinant dna technique for the preparation of a protein resembling human interferon

Country Status (1)

Country Link
GB (1) GB2068970B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
CA1341604C (en) 1980-04-03 2010-05-04 Biogen N.V. Dna sequences, recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
DE3176011D1 (en) * 1980-06-12 1987-04-23 Japan Found Cancer Plasmid
NZ198445A (en) * 1980-09-25 1984-05-31 Genentech Inc Production of human fibroblast interferon by recombinant dna technology
DK489481A (en) * 1980-11-10 1982-05-11 Searle & Co PLASMID VECTOR AND METHOD OF PRODUCING THEREOF
US5582824A (en) * 1981-10-19 1996-12-10 Genentech, Inc. Recombinant DES-CYS-TYR-CYS human immune interferon
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
US4450103A (en) * 1982-03-01 1984-05-22 Cetus Corporation Process for recovering human IFN-β from a transformed microorganism
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
DE3220116A1 (en) * 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach MICROBIOLOGICALLY MANUFACTURED (ALPHA) AND SS INTERFERONES, DNA SEQUENCES CODING FOR THESE INTERFERONES, MICROORGANISMS CONTAINING THIS GENETIC INFORMATION, AND METHOD FOR THE PRODUCTION THEREOF
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor

Also Published As

Publication number Publication date
GB2068970A (en) 1981-08-19

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee