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GB1536195A - 3-phenyl-sec-butylamine derivatives - Google Patents

3-phenyl-sec-butylamine derivatives

Info

Publication number
GB1536195A
GB1536195A GB6837/76A GB683776A GB1536195A GB 1536195 A GB1536195 A GB 1536195A GB 6837/76 A GB6837/76 A GB 6837/76A GB 683776 A GB683776 A GB 683776A GB 1536195 A GB1536195 A GB 1536195A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
alkyl group
sec
phenyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6837/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of GB1536195A publication Critical patent/GB1536195A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/49—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/52—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

3-Phenyl-sec-butylamine derivatives of the formula I <IMAGE> in which R<1> and R<2>, which are identical or different, are hydrogen, an alkyl group with 1 to 5 carbon atoms or a halogen atom, R<3> is an alkyl group with 1 to 5 carbon atoms or the benzyl group, R<4> is hydrogen, an alkyl group with 1 to 5 carbon atoms or the benzyl group, where R<1> and/or R<2> are an alkyl group with 1 to 5 carbon atoms or a halogen atom when R<3> and R<4> are the methyl group, are valuable antidepressants which have a lower euphoric or central stimulant effect than amphetamine; they are also valuable agents for eliminating anxiety states. They are prepared by reducing a compound of the formula II <IMAGE> in which A is -CH2-CH2- or -CH=CH-.
GB6837/76A 1975-02-21 1976-02-20 3-phenyl-sec-butylamine derivatives Expired GB1536195A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7501956A SE396748B (en) 1975-02-21 1975-02-21 PROCEDURE FOR PREPARATION OF 3-PHENYL-SEC -BUTYLAMINE DERIVATIVES

Publications (1)

Publication Number Publication Date
GB1536195A true GB1536195A (en) 1978-12-20

Family

ID=20323758

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6837/76A Expired GB1536195A (en) 1975-02-21 1976-02-20 3-phenyl-sec-butylamine derivatives

Country Status (12)

Country Link
AT (1) AT340384B (en)
AU (1) AU499650B2 (en)
BE (1) BE838739A (en)
CA (1) CA1078408A (en)
CH (1) CH609673A5 (en)
DE (1) DE2606393A1 (en)
FR (1) FR2301236A2 (en)
GB (1) GB1536195A (en)
IE (1) IE43129B1 (en)
LU (1) LU74386A1 (en)
NL (1) NL7601605A (en)
SE (1) SE396748B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU701981B2 (en) 1995-12-21 1999-02-11 Sumitomo Chemical Company, Limited Triazole derivatives and uses thereof

Also Published As

Publication number Publication date
ATA82076A (en) 1977-04-15
LU74386A1 (en) 1977-01-06
AT340384B (en) 1977-12-12
BE838739A (en) 1976-08-20
SE396748B (en) 1977-10-03
CH609673A5 (en) 1979-03-15
FR2301236B2 (en) 1980-07-04
NL7601605A (en) 1976-08-24
FR2301236A2 (en) 1976-09-17
CA1078408A (en) 1980-05-27
IE43129B1 (en) 1980-12-31
IE43129L (en) 1976-08-21
AU1124776A (en) 1977-08-25
AU499650B2 (en) 1979-04-26
DE2606393A1 (en) 1976-09-09
SE7501956L (en) 1976-08-23

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee