GB1535778A - Compounds useful in treatment of unipolar depression - Google Patents
Compounds useful in treatment of unipolar depressionInfo
- Publication number
- GB1535778A GB1535778A GB3652975A GB3652975A GB1535778A GB 1535778 A GB1535778 A GB 1535778A GB 3652975 A GB3652975 A GB 3652975A GB 3652975 A GB3652975 A GB 3652975A GB 1535778 A GB1535778 A GB 1535778A
- Authority
- GB
- United Kingdom
- Prior art keywords
- treatment
- tryptophan
- nicotinamide
- unipolar depression
- compounds useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 208000020401 Depressive disease Diseases 0.000 title abstract 2
- 201000003104 endogenous depression Diseases 0.000 title abstract 2
- 208000024714 major depressive disease Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 abstract 6
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 5
- 229960003966 nicotinamide Drugs 0.000 abstract 3
- 235000005152 nicotinamide Nutrition 0.000 abstract 3
- 239000011570 nicotinamide Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 229960004799 tryptophan Drugs 0.000 abstract 2
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003701 inert diluent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1535778 L-Tryptophan and nicotinamide compositions D A MAC-SWEENEY 6 Dec 1976 [4 Sept 1975] 36529/75 Heading A5B Pharmaceutical compositions for the treatment of unipolar depression comprise only L-tryptophan and nicotinamide each in a medicinally active quantity and a pharmaceutically acceptable inert diluent or carrier. The compositions may be administered orally in the form of tablets. Preferably a unit dosage form comprises about 3 grams L- tryptophan and 0.75 grams nicotinamide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3652975A GB1535778A (en) | 1976-12-06 | 1976-12-06 | Compounds useful in treatment of unipolar depression |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3652975A GB1535778A (en) | 1976-12-06 | 1976-12-06 | Compounds useful in treatment of unipolar depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1535778A true GB1535778A (en) | 1978-12-13 |
Family
ID=10388988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3652975A Expired GB1535778A (en) | 1976-12-06 | 1976-12-06 | Compounds useful in treatment of unipolar depression |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1535778A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2512672A1 (en) * | 1981-09-16 | 1983-03-18 | Panmedica | Medicaments for treating serotonin deficiency - contg. 5-hydroxy-tryptophan and heterocyclic nitrogen cpd. |
| EP0074909A1 (en) * | 1981-09-16 | 1983-03-23 | S.A. PANMEDICA Société dite: | Compositions on the basis of 5-hydroxy-tryptophane, manufacturing process and medicaments containing them |
| DE3912232A1 (en) * | 1989-04-11 | 1989-11-30 | Klosa Josef | Remedy for urinary incontinence |
| WO2005039546A3 (en) * | 2003-10-03 | 2007-10-04 | Veijlen N V | Use of indoleacetic acid derivatives which increase the serum igf-1 level for the preparation of a therapeutical composition for treatment of various diseases |
| RU2361583C2 (en) * | 2003-10-03 | 2009-07-20 | Вейлен Н.В. | Application of compositions, capable to raise level of igf-1 in blood serum, at preparation of therapeutic composition for treatment of stages of various diseases, associated with depression of igf-1 level in serum of people and animals |
| US8883233B2 (en) | 2003-10-03 | 2014-11-11 | Veijlen N.V. | Animal feed composition |
-
1976
- 1976-12-06 GB GB3652975A patent/GB1535778A/en not_active Expired
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2512672A1 (en) * | 1981-09-16 | 1983-03-18 | Panmedica | Medicaments for treating serotonin deficiency - contg. 5-hydroxy-tryptophan and heterocyclic nitrogen cpd. |
| EP0074909A1 (en) * | 1981-09-16 | 1983-03-23 | S.A. PANMEDICA Société dite: | Compositions on the basis of 5-hydroxy-tryptophane, manufacturing process and medicaments containing them |
| US4472387A (en) * | 1981-09-16 | 1984-09-18 | Panmedica S.A. | Pharmaceutical compositions capable of increasing cerebral serotonin concentration |
| DE3912232A1 (en) * | 1989-04-11 | 1989-11-30 | Klosa Josef | Remedy for urinary incontinence |
| WO2005039546A3 (en) * | 2003-10-03 | 2007-10-04 | Veijlen N V | Use of indoleacetic acid derivatives which increase the serum igf-1 level for the preparation of a therapeutical composition for treatment of various diseases |
| RU2361583C2 (en) * | 2003-10-03 | 2009-07-20 | Вейлен Н.В. | Application of compositions, capable to raise level of igf-1 in blood serum, at preparation of therapeutic composition for treatment of stages of various diseases, associated with depression of igf-1 level in serum of people and animals |
| US8883233B2 (en) | 2003-10-03 | 2014-11-11 | Veijlen N.V. | Animal feed composition |
| US9408405B2 (en) | 2003-10-03 | 2016-08-09 | Veijlen N.V. | Use of compounds that are able to increase the serum IGF-1 level for the preparation of a therapeutical composition for treatment of various disease states associated with a reduced IGF-1 serum level in humans and animals |
| US10716778B2 (en) | 2003-10-03 | 2020-07-21 | Veijlen | Use of compounds that are able to increase the serum IGF-1 level for the preparation of a therapeutical composition for treatment of various disease states associated with a reduced IGF-1 serum level in humans and animals |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |