GB1529195A - Coagulation rate method and apparatus - Google Patents
Coagulation rate method and apparatusInfo
- Publication number
- GB1529195A GB1529195A GB4445075A GB4445075A GB1529195A GB 1529195 A GB1529195 A GB 1529195A GB 4445075 A GB4445075 A GB 4445075A GB 4445075 A GB4445075 A GB 4445075A GB 1529195 A GB1529195 A GB 1529195A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cylinder
- fluid
- coagulation time
- coagulation
- combined
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000015271 coagulation Effects 0.000 title abstract 4
- 238000005345 coagulation Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title 1
- 239000012530 fluid Substances 0.000 abstract 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- PGOHTUIFYSHAQG-LJSDBVFPSA-N (2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]hexanoic acid Chemical compound CSCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O PGOHTUIFYSHAQG-LJSDBVFPSA-N 0.000 abstract 1
- 239000004606 Fillers/Extenders Substances 0.000 abstract 1
- 239000001828 Gelatine Substances 0.000 abstract 1
- 102000002262 Thromboplastin Human genes 0.000 abstract 1
- 108010000499 Thromboplastin Proteins 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- BULVZWIRKLYCBC-UHFFFAOYSA-N phorate Chemical compound CCOP(=S)(OCC)SCSCC BULVZWIRKLYCBC-UHFFFAOYSA-N 0.000 abstract 1
- 239000000377 silicon dioxide Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
1529195 Measuring blood coagulation time GEOMET Inc 28 Oct 1975 44450/75 Heading G1B The coagulation time of a fluid which has been combined with reagent capable of increasing its viscosity, for example of blood previously combined with reagent comprising in lyophilized form thromboplastin, gelatine and to make the composition porous for rapid dissolution, formed silica as an extender, is determined by introducing the fluid into one end of a hollow cylinder, supporting the cylinder so that the fluid moves downwardly and determining the coagulation time from the distance the sample travels before coagulation immobilizes it in the cylinder. The rate of descent may be controlled by means of a limiting orifice at the outlet end of the cylinder as shown or by means of projections on the inner surface of the cylinder or using a porous plug.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4445075A GB1529195A (en) | 1975-10-28 | 1975-10-28 | Coagulation rate method and apparatus |
| FR7533196A FR2330008A1 (en) | 1975-10-28 | 1975-10-30 | METHOD AND DEVICE FOR THE RAPID ESTIMATION OF COAGULATION RATES |
| DE19752549231 DE2549231A1 (en) | 1975-10-28 | 1975-11-03 | METHOD AND DEVICE FOR REPRODUCIBLE MEASUREMENT OF THE COAGULATION RATE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4445075A GB1529195A (en) | 1975-10-28 | 1975-10-28 | Coagulation rate method and apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1529195A true GB1529195A (en) | 1978-10-18 |
Family
ID=10433336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4445075A Expired GB1529195A (en) | 1975-10-28 | 1975-10-28 | Coagulation rate method and apparatus |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE2549231A1 (en) |
| FR (1) | FR2330008A1 (en) |
| GB (1) | GB1529195A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0014039A1 (en) * | 1979-01-08 | 1980-08-06 | Ortho Diagnostic Systems Inc. | A method involving a one-stage prothrombin time test for determining a blood clotting mechanism |
| EP0483117A3 (en) * | 1985-08-05 | 1992-09-23 | Biotrack, Inc. | Capillary flow device |
| US5300779A (en) * | 1985-08-05 | 1994-04-05 | Biotrack, Inc. | Capillary flow device |
| CN111551701A (en) * | 2020-04-03 | 2020-08-18 | 深圳大学 | Flexible micro-column ring array for detecting clot contractility and preparation method and application thereof |
-
1975
- 1975-10-28 GB GB4445075A patent/GB1529195A/en not_active Expired
- 1975-10-30 FR FR7533196A patent/FR2330008A1/en active Granted
- 1975-11-03 DE DE19752549231 patent/DE2549231A1/en not_active Ceased
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0014039A1 (en) * | 1979-01-08 | 1980-08-06 | Ortho Diagnostic Systems Inc. | A method involving a one-stage prothrombin time test for determining a blood clotting mechanism |
| EP0483117A3 (en) * | 1985-08-05 | 1992-09-23 | Biotrack, Inc. | Capillary flow device |
| US5300779A (en) * | 1985-08-05 | 1994-04-05 | Biotrack, Inc. | Capillary flow device |
| CN111551701A (en) * | 2020-04-03 | 2020-08-18 | 深圳大学 | Flexible micro-column ring array for detecting clot contractility and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2330008A1 (en) | 1977-05-27 |
| DE2549231A1 (en) | 1977-05-12 |
| FR2330008B1 (en) | 1981-09-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES457430A1 (en) | Material layer volume determination | |
| GB1530669A (en) | Method of preparing a liquid substance for analysis | |
| JPS5352483A (en) | Detecting method for concrete construction destruction | |
| CA1006008A (en) | Method and apparatus for determining the viscosity of a liquid sample | |
| GB1529195A (en) | Coagulation rate method and apparatus | |
| FR2313264A1 (en) | APPARATUS FOR INDICATING THE RATE OF ICING, IN PARTICULAR ON AIRCRAFT | |
| CA1034888A (en) | Method and device for the continuous automatic analysis of the "filterability point" of liquid substances, particularly diesel oil | |
| GB1414487A (en) | Method of obtaining a column of liquid within an open-ended tube and a tube device for carrying out the method | |
| BE831417A (en) | PROCESS FOR THE PREPARATION OF THIENO (3,2-C) PYRIDINE AND THIENO (2,3-C) PYRIDINE | |
| SE437303B (en) | PROCEDURE FOR ON-LINE Saturation of the concentration of an analyte in a container, as well as apparatus for performing the procedure | |
| JPS5537152A (en) | Immobilized enzyme column | |
| DK303877A (en) | PROCEDURE FOR THE PRODUCTION OF REINFORCEMENTS FOR HOLE CONCRETE BODIES AND APPARATUS FOR CARRYING OUT THE PROCEDURE | |
| SU684381A1 (en) | Method of determining plasticity zone dimensions at testing metal specimans for destruction viscosity | |
| JPS5237087A (en) | Isotope analysis method by use of raman effect | |
| JPS55157334A (en) | Inserting amount setting apparatus of inspecting liquid into pipette | |
| JPS51134651A (en) | Detection method of the thickness of asphalt pavement | |
| JPS5249086A (en) | Method and apparatus for measuring temperature and sampling of molten steel flow | |
| JPS528583A (en) | Device and method for continuous cutting and injection of glass fiber | |
| JPS5433792A (en) | Electrophoresis analyzer | |
| GB1509911A (en) | Method of and apparatus for determining the filtrability index of liquids | |
| OA04719A (en) | Method and device for the production of alcohol-free beer. | |
| JPS5329193A (en) | Uniform speed electrophoresis analyzer | |
| JPS5240384A (en) | Method of detecting pressure of high viscosity fluid | |
| JPS5245956A (en) | Method and system for measuring distribution of substance sticked to s urface of string | |
| JPS53109691A (en) | Flow cell type analysis method and apparatus liquid for specimen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |