GB1528043A - Process for the preparation of nitrile derivatives - Google Patents
Process for the preparation of nitrile derivativesInfo
- Publication number
- GB1528043A GB1528043A GB2886975A GB2886975A GB1528043A GB 1528043 A GB1528043 A GB 1528043A GB 2886975 A GB2886975 A GB 2886975A GB 2886975 A GB2886975 A GB 2886975A GB 1528043 A GB1528043 A GB 1528043A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- nitrile derivatives
- july
- benzyl
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002825 nitriles Chemical class 0.000 title 1
- -1 Substituted-benzyl Chemical group 0.000 abstract 3
- 150000007962 benzene acetonitriles Chemical class 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 125000001930 alkyl chloride group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052740 iodine Chemical group 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1528043 Preparation of substituted benzyl nitrile derivatives SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ BV 7 July 1976 [9 July 1975 (2)] 28869/75 and 28900/75 Heading C2C Substituted-benzyl nitrile derivatives of the general formulain which Hal refers to halogen atom and R<SP>1</SP> and R<SP>2</SP> each represents an alkyl group of 1-4 carbon atoms are prepared by (a) reacting a benzyl halide of the general formula in which X represents a chlorine, bromine or iodine atom, with a substantially equimolar amount of an alkali metal cyanide and a quaternary ammonium compound, either in the absence of added water or using a volume ratio of water to the compound of Formula II below 0À1 : 1, and (b) reacting the benzyl nitrile derivative of formula thus formed with a molar excess of a secondary alkyl chloride of the formula R<SP>1</SP>R<SP>2</SP>CHO in the presence of an alkali metal hydroxide.
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2886975A GB1528043A (en) | 1975-07-09 | 1975-07-09 | Process for the preparation of nitrile derivatives |
| US05/699,815 US4056509A (en) | 1975-07-09 | 1976-06-24 | Preparation of benzyl cyanides |
| IL49985A IL49985A (en) | 1975-07-09 | 1976-07-06 | Preparation of benzyl nitrile derivatives |
| DE19762630633 DE2630633A1 (en) | 1975-07-09 | 1976-07-07 | PROCESS FOR PREPARING SUBSTITUTED BENZYL NITRILE DERIVATIVES |
| CH871376A CH619447A5 (en) | 1975-07-09 | 1976-07-07 | |
| NLAANVRAGE7607483,A NL187392C (en) | 1975-07-09 | 1976-07-07 | PROCESS FOR PREPARING 4-CHLOROUS-ALFA-ISOPROPYLBENZYLCYANIDE. |
| JP51080036A JPS5933584B2 (en) | 1975-07-09 | 1976-07-07 | Substituted benzylnitrile derivatives |
| BR4436/76A BR7604436A (en) | 1975-07-09 | 1976-07-07 | PROCESS FOR THE PREPARATION OF REPLACED BENZYL-NITRILLA DERIVATIVES |
| FR7620734A FR2317281A1 (en) | 1975-07-09 | 1976-07-07 | PROCESS FOR THE PREPARATION OF NITRILE DERIVATIVES |
| DD193744A DD125678A5 (en) | 1975-07-09 | 1976-07-07 | |
| IT25100/76A IT1062521B (en) | 1975-07-09 | 1976-07-07 | PROCESS FOR THE PREPARATION OF NITRILE DERIVATIVES |
| HU76SE1840A HU174381B (en) | 1975-07-09 | 1976-07-08 | Process for preparing nitrile derivatives |
| AU15776/76A AU500150B2 (en) | 1975-07-09 | 1976-07-09 | Benzyl nitrile derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2886975A GB1528043A (en) | 1975-07-09 | 1975-07-09 | Process for the preparation of nitrile derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1528043A true GB1528043A (en) | 1978-10-11 |
Family
ID=10282475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2886975A Expired GB1528043A (en) | 1975-07-09 | 1975-07-09 | Process for the preparation of nitrile derivatives |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1528043A (en) |
-
1975
- 1975-07-09 GB GB2886975A patent/GB1528043A/en not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19940707 |