GB1525765A - Injectable solution - Google Patents
Injectable solutionInfo
- Publication number
- GB1525765A GB1525765A GB33481/76A GB3348176A GB1525765A GB 1525765 A GB1525765 A GB 1525765A GB 33481/76 A GB33481/76 A GB 33481/76A GB 3348176 A GB3348176 A GB 3348176A GB 1525765 A GB1525765 A GB 1525765A
- Authority
- GB
- United Kingdom
- Prior art keywords
- parts
- injectable solution
- aug
- mixture
- time
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940102223 injectable solution Drugs 0.000 title abstract 2
- BSYNRYMUTXBXSQ-FOQJRBATSA-N 59096-14-9 Chemical compound CC(=O)OC1=CC=CC=C1[14C](O)=O BSYNRYMUTXBXSQ-FOQJRBATSA-N 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000004475 Arginine Substances 0.000 abstract 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
- A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1525765 Injectable aspirin LABORATOIRES UP SA 11 Aug 1976 [11 Aug 1975] 33481/76 Heading A5B An injectable solution is prepared by mixing, at the time of use, 20-100 parts by weight of solid acetyl salicylic acid, with a mixture of 105-150 parts arginine and/or lysine, 10-100 parts of at least one amino acid having two acid groups and a pK a greater than acetyl salicylic acid, and 1000 parts water. The mixture may also contain histidine, and 10-300 parts of a sugar and/or glycine may be added at the time of use.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7524981A FR2320759A1 (en) | 1975-08-11 | 1975-08-11 | EXTEMPORANEOUS ACETYLSALICYLIC ACID SOLUTION FOR INJECTION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1525765A true GB1525765A (en) | 1978-09-20 |
Family
ID=9158984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB33481/76A Expired GB1525765A (en) | 1975-08-11 | 1976-08-11 | Injectable solution |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5241212A (en) |
| AU (1) | AU1673776A (en) |
| BE (1) | BE845038A (en) |
| DE (1) | DE2635843A1 (en) |
| ES (1) | ES450583A1 (en) |
| FR (1) | FR2320759A1 (en) |
| GB (1) | GB1525765A (en) |
| NL (1) | NL7608951A (en) |
| SE (1) | SE7608909L (en) |
| ZA (1) | ZA764781B (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2240041B (en) * | 1989-12-22 | 1993-09-01 | Scras | Agents for blocking endothelin derived relaxing factor |
| ES2052452A1 (en) * | 1992-01-04 | 1994-07-01 | Sod Conseils Rech Applic | Dual inhibitors of no synthase and cyclooxygenase, process for their preparation and therapeutical compositions containing them |
| EP1739086A3 (en) * | 2005-06-29 | 2007-02-28 | Verisfield (UK) Ltd. | Pharmaceutical compositions of risperidone in aqueous solution |
| CN101380329B (en) * | 2008-10-29 | 2010-11-17 | 海南本创医药科技有限公司 | Preparation method of arginine aspirin and powder and injection preparation thereof |
| WO2010130396A3 (en) * | 2009-05-11 | 2011-10-27 | King Saud University | Preparation of acetyl salicylic acid/glutamic acid complex for oral administration |
| US11369581B2 (en) | 2016-06-28 | 2022-06-28 | Asamedic As | Two component composition |
| US11844806B2 (en) | 2017-12-22 | 2023-12-19 | Asamedic As | Compositions comprising acetylsalicylic acid and a phosphate salt |
| US11850253B2 (en) | 2017-12-22 | 2023-12-26 | Asamedic As | Two component compositions |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6021570B2 (en) * | 1978-07-04 | 1985-05-28 | 三共株式会社 | Method for manufacturing high concentration preparations of DOPAs |
| FR2495608A1 (en) * | 1980-12-04 | 1982-06-11 | Morelle Jean | NEW ASPARTIC ACID DERIVATIVES AND THEIR USES |
| CN102531969A (en) * | 2011-12-28 | 2012-07-04 | 蚌埠丰原医药科技发展有限公司 | Method for preparing sterile L-arginine |
| WO2023198294A1 (en) | 2022-04-14 | 2023-10-19 | Hyloris Developments Sa | Acetyl salicylic acid composition for intravenous administration, its storage, production and use |
-
1975
- 1975-08-11 FR FR7524981A patent/FR2320759A1/en active Granted
-
1976
- 1976-08-09 ES ES450583A patent/ES450583A1/en not_active Expired
- 1976-08-09 ZA ZA764781A patent/ZA764781B/en unknown
- 1976-08-10 BE BE2055232A patent/BE845038A/en unknown
- 1976-08-10 DE DE19762635843 patent/DE2635843A1/en active Pending
- 1976-08-10 SE SE7608909A patent/SE7608909L/en unknown
- 1976-08-11 NL NL7608951A patent/NL7608951A/en not_active Application Discontinuation
- 1976-08-11 GB GB33481/76A patent/GB1525765A/en not_active Expired
- 1976-08-11 AU AU16737/76A patent/AU1673776A/en not_active Expired
- 1976-08-11 JP JP51095886A patent/JPS5241212A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2240041B (en) * | 1989-12-22 | 1993-09-01 | Scras | Agents for blocking endothelin derived relaxing factor |
| AT403122B (en) * | 1989-12-22 | 1997-11-25 | Sod Conseils Rech Applic | THERAPEUTIC INFUSION PREPARATION BASED ON AMINO ACID DERIVATIVES |
| ES2052452A1 (en) * | 1992-01-04 | 1994-07-01 | Sod Conseils Rech Applic | Dual inhibitors of no synthase and cyclooxygenase, process for their preparation and therapeutical compositions containing them |
| EP1739086A3 (en) * | 2005-06-29 | 2007-02-28 | Verisfield (UK) Ltd. | Pharmaceutical compositions of risperidone in aqueous solution |
| CN101380329B (en) * | 2008-10-29 | 2010-11-17 | 海南本创医药科技有限公司 | Preparation method of arginine aspirin and powder and injection preparation thereof |
| WO2010130396A3 (en) * | 2009-05-11 | 2011-10-27 | King Saud University | Preparation of acetyl salicylic acid/glutamic acid complex for oral administration |
| US11369581B2 (en) | 2016-06-28 | 2022-06-28 | Asamedic As | Two component composition |
| US11918554B2 (en) | 2016-06-28 | 2024-03-05 | Asamedic As | Two-component composition |
| US11844806B2 (en) | 2017-12-22 | 2023-12-19 | Asamedic As | Compositions comprising acetylsalicylic acid and a phosphate salt |
| US11850253B2 (en) | 2017-12-22 | 2023-12-26 | Asamedic As | Two component compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2320759B1 (en) | 1979-09-14 |
| ZA764781B (en) | 1977-07-27 |
| AU1673776A (en) | 1978-02-16 |
| FR2320759A1 (en) | 1977-03-11 |
| SE7608909L (en) | 1977-02-12 |
| BE845038A (en) | 1976-12-01 |
| ES450583A1 (en) | 1978-02-01 |
| NL7608951A (en) | 1977-02-15 |
| JPS5241212A (en) | 1977-03-30 |
| DE2635843A1 (en) | 1977-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |