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GB1549074A - Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents - Google Patents

Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents

Info

Publication number
GB1549074A
GB1549074A GB31865/76A GB3186576A GB1549074A GB 1549074 A GB1549074 A GB 1549074A GB 31865/76 A GB31865/76 A GB 31865/76A GB 3186576 A GB3186576 A GB 3186576A GB 1549074 A GB1549074 A GB 1549074A
Authority
GB
United Kingdom
Prior art keywords
atoms
biguanides
compositions containing
oral compositions
trifluoromethyl phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31865/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/669,930 external-priority patent/US4067962A/en
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of GB1549074A publication Critical patent/GB1549074A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Cosmetics (AREA)
  • Confectionery (AREA)

Abstract

A composition for oral and/or dental care, e.g. in the form of a tooth cleaning agent or mouthwash or chewing gum, contains a vehicle for use in the oral cavity and antiplaque agent of the formula (1) <IMAGE> in which n is a number from 1 up to and including 4, X and X' are each an alkylene radical which contains 1-3 C atoms, z and z' are zero or one, R and R' are each hydrogen atoms, alkyl radicals with 1-12 C atoms or aralkyl radicals with 7-12 C atoms, and R2 and R2' are each hydrogen atoms or alkyl radicals with 1-2 C atoms, or a pharmacologically acceptable salt of a compound of the formula (1).
GB31865/76A 1975-08-01 1976-07-30 Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents Expired GB1549074A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60124475A 1975-08-01 1975-08-01
US05/669,930 US4067962A (en) 1975-08-01 1976-03-24 Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents

Publications (1)

Publication Number Publication Date
GB1549074A true GB1549074A (en) 1979-08-01

Family

ID=27083824

Family Applications (1)

Application Number Title Priority Date Filing Date
GB31865/76A Expired GB1549074A (en) 1975-08-01 1976-07-30 Oral compositions containing trifluoromethyl phenyl bis-biguanides as antiplaque agents

Country Status (13)

Country Link
JP (1) JPS5254036A (en)
AT (1) AT348682B (en)
CH (1) CH621938A5 (en)
DE (1) DE2633651A1 (en)
DK (1) DK343676A (en)
ES (1) ES450364A1 (en)
FR (1) FR2319336A1 (en)
GB (1) GB1549074A (en)
IE (1) IE43411B1 (en)
IT (1) IT1062647B (en)
LU (1) LU75517A1 (en)
NL (1) NL7608480A (en)
SE (2) SE429923B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2262283A (en) * 1991-12-12 1993-06-16 Mitsubishi Materials Corp Biguanide disinfectants
US8287843B2 (en) 2003-06-23 2012-10-16 Colgate-Palmolive Company Antiplaque oral care compositions
US8865135B2 (en) 2003-06-23 2014-10-21 Colgate-Palmolive Company Stable dentifrice compositions

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2262283A (en) * 1991-12-12 1993-06-16 Mitsubishi Materials Corp Biguanide disinfectants
DE4241491A1 (en) * 1991-12-12 1993-06-17 Mitsubishi Materials Corp
US5478864A (en) * 1991-12-12 1995-12-26 Mitsubishi Materials Corp. Method for disinfection using a 1,n-bis(N5 -trifluoromethyl-phenyl-N1 -biguanido)-alkane
GB2262283B (en) * 1991-12-12 1996-01-17 Mitsubishi Materials Corp Biguanide disinfectants
DE4241491C2 (en) * 1991-12-12 1998-05-20 Mitsubishi Materials Corp Use of bisbiguanide compounds
US8287843B2 (en) 2003-06-23 2012-10-16 Colgate-Palmolive Company Antiplaque oral care compositions
US8865135B2 (en) 2003-06-23 2014-10-21 Colgate-Palmolive Company Stable dentifrice compositions

Also Published As

Publication number Publication date
SE429923B (en) 1983-10-10
SE8008721L (en) 1980-12-11
IE43411L (en) 1977-02-01
JPS5254036A (en) 1977-05-02
NL7608480A (en) 1977-02-03
LU75517A1 (en) 1977-04-20
FR2319336A1 (en) 1977-02-25
SE7608566L (en) 1977-02-02
IT1062647B (en) 1984-10-20
DK343676A (en) 1977-02-02
ES450364A1 (en) 1977-08-16
IE43411B1 (en) 1981-02-25
CH621938A5 (en) 1981-03-13
ATA566776A (en) 1978-07-15
DE2633651A1 (en) 1977-02-17
FR2319336B1 (en) 1979-07-13
AT348682B (en) 1979-02-26

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee