GB1432345A - Ophthalmic compositions and contact lens disinfecting compo sitions - Google Patents
Ophthalmic compositions and contact lens disinfecting compo sitionsInfo
- Publication number
- GB1432345A GB1432345A GB1700572A GB1700572A GB1432345A GB 1432345 A GB1432345 A GB 1432345A GB 1700572 A GB1700572 A GB 1700572A GB 1700572 A GB1700572 A GB 1700572A GB 1432345 A GB1432345 A GB 1432345A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ophthalmic
- contact lens
- diguanide
- compositions
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- 230000000249 desinfective effect Effects 0.000 title abstract 3
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- QCHFTSOMWOSFHM-WPRPVWTQSA-N (+)-Pilocarpine Chemical compound C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C QCHFTSOMWOSFHM-WPRPVWTQSA-N 0.000 abstract 1
- QCHFTSOMWOSFHM-UHFFFAOYSA-N SJ000285536 Natural products C1OC(=O)C(CC)C1CC1=CN=CN1C QCHFTSOMWOSFHM-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 abstract 1
- 229960005091 chloramphenicol Drugs 0.000 abstract 1
- 229940023490 ophthalmic product Drugs 0.000 abstract 1
- 125000005515 organic divalent group Chemical group 0.000 abstract 1
- 229960001416 pilocarpine Drugs 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 abstract 1
- 229960004906 thiomersal Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
- C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/141—Biguanides, e.g. chlorhexidine
- A61L12/142—Polymeric biguanides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Eyeglasses (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1432345 Ophthalmic compositions; disinfecting contact lenses SMITH & NEPHEW RESEARCH Ltd 4 April 1973 [13 April 1972] 17005/72 Headings A5B and A5E An ophthalmic composition or a contact lens disinfecting composition comprises an aqueous solution of at least one ophthalmically acceptable polymeric diguanide of the formula: in which each end of the polymeric diguanide is independently terminated either by an amino group or by an group and in which Z represents an organic divalent bridging group which may be the same or different throughout the polymer and n is at least 3, and/or at least one ophthalmically acceptable salt thereof, the diguanide and/or its salt being present in a total amount of from 0.0005 to 0.05% by weight based on the total weight of the composition. The compositions may contain a mixture of the diguanides and may contain additional bactericides such as thiomersal, benzalkonium chloride and phenylmercuric salts and ophthalmic drugs such as pilocarpine, chloramphenicol and steroids.
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1700572A GB1432345A (en) | 1972-04-13 | 1972-04-13 | Ophthalmic compositions and contact lens disinfecting compo sitions |
| ZA732395A ZA732395B (en) | 1972-04-13 | 1973-04-05 | Compositions for ophthalmic use and for use with contact lenses and methods of treating contact lenses |
| AU54335/73A AU5433573A (en) | 1972-04-13 | 1973-04-10 | Bactericidal compositions for storage of contact lenses |
| DE2318137A DE2318137A1 (en) | 1972-04-13 | 1973-04-11 | MEANS FOR EYES AND CONTACT LENSES |
| FR7313223A FR2182962B1 (en) | 1972-04-13 | 1973-04-12 | |
| JP48041498A JPS4918043A (en) | 1972-04-13 | 1973-04-13 | |
| NL7305180A NL7305180A (en) | 1972-04-13 | 1973-04-13 | |
| IT7349462A IT983030B (en) | 1972-04-13 | 1973-04-13 | WATER COMPOSITION POLYMER USEFUL FOR USE IN ASSOCIATION WITH CONTACT OPHTHALMIC LENSES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1700572A GB1432345A (en) | 1972-04-13 | 1972-04-13 | Ophthalmic compositions and contact lens disinfecting compo sitions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1432345A true GB1432345A (en) | 1976-04-14 |
Family
ID=10087528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1700572A Expired GB1432345A (en) | 1972-04-13 | 1972-04-13 | Ophthalmic compositions and contact lens disinfecting compo sitions |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS4918043A (en) |
| AU (1) | AU5433573A (en) |
| DE (1) | DE2318137A1 (en) |
| FR (1) | FR2182962B1 (en) |
| GB (1) | GB1432345A (en) |
| IT (1) | IT983030B (en) |
| NL (1) | NL7305180A (en) |
| ZA (1) | ZA732395B (en) |
Cited By (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405645A (en) | 1980-04-02 | 1983-09-20 | Wella Aktiengesellschaft | Treatment of dandruff with biguanides |
| US4438011A (en) | 1980-12-18 | 1984-03-20 | Smith And Nephew Associated Companies Limited | Method for sterilizing soft contact lens |
| US4504405A (en) * | 1980-12-18 | 1985-03-12 | Smith And Nephew Associated Companies P.L.C. | Method of cleaning soft contact lenses |
| US4537746A (en) * | 1983-12-29 | 1985-08-27 | Bausch & Lomb Incorporated | Methods for disinfecting and preserving contact lenses |
| WO1986002001A1 (en) * | 1984-09-28 | 1986-04-10 | Bausch & Lomb Incorporated | Cosmetic compositions |
| JPS62500661A (en) * | 1984-09-28 | 1987-03-19 | ボ−シユ アンド ロ−ム インコ−ポレイテイド | cosmetic composition |
| US4758595A (en) * | 1984-12-11 | 1988-07-19 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| US4783488A (en) * | 1987-01-31 | 1988-11-08 | Bausch & Lomb Incorporated | Contact lens wetting solution |
| US4836986A (en) * | 1984-09-28 | 1989-06-06 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| US4891423A (en) * | 1989-03-20 | 1990-01-02 | Stockel Richard F | Polymeric biguanides |
| US5422073A (en) * | 1990-12-27 | 1995-06-06 | Allergan, Inc. | Method and composition for disinfecting contact lenses |
| EP0788797A1 (en) * | 1996-02-08 | 1997-08-13 | Fresenius AG | Use of PHMB for the treatment of infections caused by intracellularly propagating germs |
| WO1997036487A1 (en) * | 1996-04-01 | 1997-10-09 | Norton Healthcare Ltd. | Disinfectant solutions containing polyhexamethylene biguanides |
| NL1005658C2 (en) * | 1997-03-27 | 1998-09-29 | Jon Holding B V | Aqueous fluid for storing contact lenses |
| WO1999024543A1 (en) * | 1997-11-12 | 1999-05-20 | Bausch & Lomb Incorporated | Disinfecting contact lenses with polyquaterniums and polymeric biguanides |
| WO1999024542A1 (en) * | 1997-11-12 | 1999-05-20 | Bausch & Lomb Incorporated | Disinfecting contact lenses with bis(biguanides) and polymeric biguanides |
| WO1999024541A1 (en) * | 1997-11-12 | 1999-05-20 | Bausch & Lomb Incorporated | Cleaning and disinfecting contact lenses with a biguanide and a phosphate-borate buffer |
| WO1999026669A1 (en) * | 1997-11-26 | 1999-06-03 | Allergan Sales, Inc. | Multi-purpose contact lens care compositions |
| US5965088A (en) * | 1997-10-23 | 1999-10-12 | Lever; Andrea M. | Method for providing rapid disinfection of contact lenses |
| US6309658B1 (en) | 1997-11-12 | 2001-10-30 | Bausch & Lomb Incorporated | Treatment of contact lenses with aqueous solution comprising a carbonate salt for enhanced cleaning |
| US6586377B2 (en) | 1997-11-26 | 2003-07-01 | Advanced Medical Optics, Inc. | Contact lens cleaning compositions |
| EP1353709A1 (en) | 2001-01-12 | 2003-10-22 | Novartis AG | Lens care product containing dexpanthenol |
| JP3497101B2 (en) | 1998-07-01 | 2004-02-16 | ロレアル | Cosmetic and / or dermatological two-phase composition especially usable for removal of eye makeup |
| US6805836B2 (en) | 2000-12-15 | 2004-10-19 | Bausch & Lomb Incorporated | Prevention of preservative uptake into biomaterials |
| US7419944B2 (en) | 2000-11-29 | 2008-09-02 | Novartis Ag | Aqueous disinfecting systems |
| CN101524554B (en) * | 2009-04-08 | 2012-08-01 | 上海卫康光学眼镜有限公司 | Composition used with contact lens for cleaning and disinfection and application thereof |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57190162A (en) * | 1981-05-19 | 1982-11-22 | Nissan Motor Co Ltd | Preventive mechanism of gear disengagement |
| JPH0892017A (en) * | 1994-09-19 | 1996-04-09 | Tomey Technol Corp | Solution preparation for contact lens |
| JP3698832B2 (en) * | 1996-10-08 | 2005-09-21 | 株式会社メニコン | Contact lens solution |
-
1972
- 1972-04-13 GB GB1700572A patent/GB1432345A/en not_active Expired
-
1973
- 1973-04-05 ZA ZA732395A patent/ZA732395B/en unknown
- 1973-04-10 AU AU54335/73A patent/AU5433573A/en not_active Expired
- 1973-04-11 DE DE2318137A patent/DE2318137A1/en active Pending
- 1973-04-12 FR FR7313223A patent/FR2182962B1/fr not_active Expired
- 1973-04-13 NL NL7305180A patent/NL7305180A/xx unknown
- 1973-04-13 JP JP48041498A patent/JPS4918043A/ja active Pending
- 1973-04-13 IT IT7349462A patent/IT983030B/en active
Cited By (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405645A (en) | 1980-04-02 | 1983-09-20 | Wella Aktiengesellschaft | Treatment of dandruff with biguanides |
| US4438011A (en) | 1980-12-18 | 1984-03-20 | Smith And Nephew Associated Companies Limited | Method for sterilizing soft contact lens |
| US4504405A (en) * | 1980-12-18 | 1985-03-12 | Smith And Nephew Associated Companies P.L.C. | Method of cleaning soft contact lenses |
| US4537746A (en) * | 1983-12-29 | 1985-08-27 | Bausch & Lomb Incorporated | Methods for disinfecting and preserving contact lenses |
| JPH06321715A (en) * | 1984-09-28 | 1994-11-22 | Bausch & Lomb Inc | Solution for disinfection preservation of contact lens |
| JPS62500661A (en) * | 1984-09-28 | 1987-03-19 | ボ−シユ アンド ロ−ム インコ−ポレイテイド | cosmetic composition |
| US4836986A (en) * | 1984-09-28 | 1989-06-06 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| WO1986002001A1 (en) * | 1984-09-28 | 1986-04-10 | Bausch & Lomb Incorporated | Cosmetic compositions |
| US4758595A (en) * | 1984-12-11 | 1988-07-19 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| US4783488A (en) * | 1987-01-31 | 1988-11-08 | Bausch & Lomb Incorporated | Contact lens wetting solution |
| US4891423A (en) * | 1989-03-20 | 1990-01-02 | Stockel Richard F | Polymeric biguanides |
| US5593637A (en) * | 1990-12-27 | 1997-01-14 | Allergan | Method and composition for disinfecting contact lenses |
| US5500186A (en) * | 1990-12-27 | 1996-03-19 | Allergan, Inc. | Method and composition for disinfecting contact lenses |
| US5422073A (en) * | 1990-12-27 | 1995-06-06 | Allergan, Inc. | Method and composition for disinfecting contact lenses |
| US5756045A (en) * | 1990-12-27 | 1998-05-26 | Allergan | Method and composition for disinfecting contact lenses |
| US5817277A (en) * | 1990-12-27 | 1998-10-06 | Allergan | Method and composition for disinfecting contact lenses |
| EP0788797A1 (en) * | 1996-02-08 | 1997-08-13 | Fresenius AG | Use of PHMB for the treatment of infections caused by intracellularly propagating germs |
| WO1997036487A1 (en) * | 1996-04-01 | 1997-10-09 | Norton Healthcare Ltd. | Disinfectant solutions containing polyhexamethylene biguanides |
| GB2329126A (en) * | 1996-04-01 | 1999-03-17 | Norton Healthcare Ltd | Disinfectant solutions containing polyhexamethylene biguanides |
| GB2329126B (en) * | 1996-04-01 | 2000-04-12 | Norton Healthcare Ltd | Disinfectant solutions |
| NL1005658C2 (en) * | 1997-03-27 | 1998-09-29 | Jon Holding B V | Aqueous fluid for storing contact lenses |
| US5965088A (en) * | 1997-10-23 | 1999-10-12 | Lever; Andrea M. | Method for providing rapid disinfection of contact lenses |
| WO1999024543A1 (en) * | 1997-11-12 | 1999-05-20 | Bausch & Lomb Incorporated | Disinfecting contact lenses with polyquaterniums and polymeric biguanides |
| US6153568A (en) * | 1997-11-12 | 2000-11-28 | Mccanna; David J. | Compositions comprising polyquaterniums in combination with polymeric biguanides for disinfecting contact lenses |
| WO1999024541A1 (en) * | 1997-11-12 | 1999-05-20 | Bausch & Lomb Incorporated | Cleaning and disinfecting contact lenses with a biguanide and a phosphate-borate buffer |
| WO1999024542A1 (en) * | 1997-11-12 | 1999-05-20 | Bausch & Lomb Incorporated | Disinfecting contact lenses with bis(biguanides) and polymeric biguanides |
| US6309658B1 (en) | 1997-11-12 | 2001-10-30 | Bausch & Lomb Incorporated | Treatment of contact lenses with aqueous solution comprising a carbonate salt for enhanced cleaning |
| US6143244A (en) * | 1997-11-12 | 2000-11-07 | Bausch & Lomb Incorporated | Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant and a complementary phosphate-borate buffer system |
| AU745778B2 (en) * | 1997-11-26 | 2002-03-28 | Abbott Medical Optics Inc. | Multi-purpose contact lens care compositions |
| US6063745A (en) * | 1997-11-26 | 2000-05-16 | Allergan | Mutli-purpose contact lens care compositions |
| US6319883B1 (en) | 1997-11-26 | 2001-11-20 | Allergan | Multi-purpose contact lens care compositions |
| WO1999026669A1 (en) * | 1997-11-26 | 1999-06-03 | Allergan Sales, Inc. | Multi-purpose contact lens care compositions |
| US6482781B2 (en) | 1997-11-26 | 2002-11-19 | Advanced Medical Optics, Inc. | Multi-purpose contact lens care compositions |
| US6586377B2 (en) | 1997-11-26 | 2003-07-01 | Advanced Medical Optics, Inc. | Contact lens cleaning compositions |
| CN100391545C (en) * | 1997-11-26 | 2008-06-04 | 先进医用光学公司 | Multipurpose contact lens care compositions |
| JP3497101B2 (en) | 1998-07-01 | 2004-02-16 | ロレアル | Cosmetic and / or dermatological two-phase composition especially usable for removal of eye makeup |
| US7419944B2 (en) | 2000-11-29 | 2008-09-02 | Novartis Ag | Aqueous disinfecting systems |
| US6805836B2 (en) | 2000-12-15 | 2004-10-19 | Bausch & Lomb Incorporated | Prevention of preservative uptake into biomaterials |
| EP1353709A1 (en) | 2001-01-12 | 2003-10-22 | Novartis AG | Lens care product containing dexpanthenol |
| CN101524554B (en) * | 2009-04-08 | 2012-08-01 | 上海卫康光学眼镜有限公司 | Composition used with contact lens for cleaning and disinfection and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2182962A1 (en) | 1973-12-14 |
| FR2182962B1 (en) | 1975-10-31 |
| JPS4918043A (en) | 1974-02-18 |
| NL7305180A (en) | 1973-10-16 |
| AU5433573A (en) | 1974-10-10 |
| ZA732395B (en) | 1974-03-27 |
| IT983030B (en) | 1974-10-31 |
| DE2318137A1 (en) | 1973-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |