GB1430464A - Tuberculin active proteins and peptides - Google Patents
Tuberculin active proteins and peptidesInfo
- Publication number
- GB1430464A GB1430464A GB3527673A GB3527673A GB1430464A GB 1430464 A GB1430464 A GB 1430464A GB 3527673 A GB3527673 A GB 3527673A GB 3527673 A GB3527673 A GB 3527673A GB 1430464 A GB1430464 A GB 1430464A
- Authority
- GB
- United Kingdom
- Prior art keywords
- peptides
- amino acid
- bacilli
- tuberculin
- active proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 101710155818 Tuberculin-active protein Proteins 0.000 title 1
- 244000052616 bacterial pathogen Species 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 241000271566 Aves Species 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229960001005 tuberculin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0006—Skin tests, e.g. intradermal testing, test strips, delayed hypersensitivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
Abstract
1430464 Peptides MITSUI PHARMACEUTICALS Inc 4 Feb 1974 35276/73 Heading C3H [Also in Division A5] Tuberculin active peptides which comprise the amino acid sequence are obtained from human, bovine or avian type tubercule bacilli by conventional extraction procedures, e.g. treatment with a lipid-dissolving solvent of heat-killed bacilli and subsequent working up of water-soluble proteinaceous material obtained therefrom, e.g. by dialysis, chromatographic, electrophoretic and gel-filtration techniques. Particular materials described include a simple protein of 89 amino acid residues (structure given) obtained from Mycobacterium tuberculosis strain aoyama B and the pentapeptide which is obtained by hydrolysis of the more complex polypeptides of the invention and subsequent separation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3527673A GB1430464A (en) | 1974-02-04 | 1974-02-04 | Tuberculin active proteins and peptides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3527673A GB1430464A (en) | 1974-02-04 | 1974-02-04 | Tuberculin active proteins and peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1430464A true GB1430464A (en) | 1976-03-31 |
Family
ID=10375894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3527673A Expired GB1430464A (en) | 1974-02-04 | 1974-02-04 | Tuberculin active proteins and peptides |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1430464A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4489158A (en) * | 1980-05-05 | 1984-12-18 | Montefiore Hospital And Medical Center, Inc. | Binding assay for the detection of mycobacteria |
| US4575484A (en) * | 1980-05-05 | 1986-03-11 | Montefiore Medical Center, Inc. | Binding assay for the detection of mycobacteria |
-
1974
- 1974-02-04 GB GB3527673A patent/GB1430464A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4489158A (en) * | 1980-05-05 | 1984-12-18 | Montefiore Hospital And Medical Center, Inc. | Binding assay for the detection of mycobacteria |
| US4575484A (en) * | 1980-05-05 | 1986-03-11 | Montefiore Medical Center, Inc. | Binding assay for the detection of mycobacteria |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |