GB1429549A - Bone-seeking technetium-99m complex - Google Patents
Bone-seeking technetium-99m complexInfo
- Publication number
- GB1429549A GB1429549A GB5357873A GB5357873A GB1429549A GB 1429549 A GB1429549 A GB 1429549A GB 5357873 A GB5357873 A GB 5357873A GB 5357873 A GB5357873 A GB 5357873A GB 1429549 A GB1429549 A GB 1429549A
- Authority
- GB
- United Kingdom
- Prior art keywords
- complex
- technetium
- seeking
- bone
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 title abstract 3
- 229940056501 technetium 99m Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- MBKDYNNUVRNNRF-UHFFFAOYSA-N medronic acid Chemical compound OP(O)(=O)CP(O)(O)=O MBKDYNNUVRNNRF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000941 radioactive substance Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
1429549 Radio-active substances RESEARCH CORP 19 Nov 1973 53578/73 Heading G6R The invention comprises a complex of technetium 99m and tin-methylene-disphosphonate. The complex may be made by mixing in aqueous solution a stannous salt, e.g. the chloride, sulphate, or acetate, methylene diphosphonic acid or a salt thereof, and a pertechnetate salt containing Tc 99 m. A solution of the complex is suitable for use by intravenous administration in skeletal imaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5357873A GB1429549A (en) | 1973-11-19 | 1973-11-19 | Bone-seeking technetium-99m complex |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5357873A GB1429549A (en) | 1973-11-19 | 1973-11-19 | Bone-seeking technetium-99m complex |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1429549A true GB1429549A (en) | 1976-03-24 |
Family
ID=10468284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5357873A Expired GB1429549A (en) | 1973-11-19 | 1973-11-19 | Bone-seeking technetium-99m complex |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1429549A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002485A1 (en) * | 1977-12-15 | 1979-06-27 | Hoechst Aktiengesellschaft | Process for the preparation of marking compositions containing tin |
| US4515766A (en) * | 1980-06-23 | 1985-05-07 | The Massachusetts General Hospital | Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium |
| CN119564888A (en) * | 2023-09-06 | 2025-03-07 | 成都云克药业有限责任公司 | Technetium [99Tc (Tc) methylene bisphosphonate oral preparation, preparation method and application thereof |
| WO2025051022A1 (en) * | 2023-09-06 | 2025-03-13 | 成都云克药业有限责任公司 | Technetium [99tc] methylene diphosphonate oral formulation, preparation method therefor, and use thereof |
-
1973
- 1973-11-19 GB GB5357873A patent/GB1429549A/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002485A1 (en) * | 1977-12-15 | 1979-06-27 | Hoechst Aktiengesellschaft | Process for the preparation of marking compositions containing tin |
| US4515766A (en) * | 1980-06-23 | 1985-05-07 | The Massachusetts General Hospital | Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium |
| CN119564888A (en) * | 2023-09-06 | 2025-03-07 | 成都云克药业有限责任公司 | Technetium [99Tc (Tc) methylene bisphosphonate oral preparation, preparation method and application thereof |
| WO2025051022A1 (en) * | 2023-09-06 | 2025-03-13 | 成都云克药业有限责任公司 | Technetium [99tc] methylene diphosphonate oral formulation, preparation method therefor, and use thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |