GB1490723A - Detoxification of gluten - Google Patents
Detoxification of glutenInfo
- Publication number
- GB1490723A GB1490723A GB46672/74A GB4667274A GB1490723A GB 1490723 A GB1490723 A GB 1490723A GB 46672/74 A GB46672/74 A GB 46672/74A GB 4667274 A GB4667274 A GB 4667274A GB 1490723 A GB1490723 A GB 1490723A
- Authority
- GB
- United Kingdom
- Prior art keywords
- enzyme
- gluten
- resin
- oct
- run
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010068370 Glutens Proteins 0.000 title abstract 3
- 235000021312 gluten Nutrition 0.000 title abstract 3
- 238000001784 detoxification Methods 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 241000228245 Aspergillus niger Species 0.000 abstract 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 239000011347 resin Substances 0.000 abstract 2
- 229920005989 resin Polymers 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 108010089934 carbohydrase Proteins 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 238000009630 liquid culture Methods 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A21—BAKING; EDIBLE DOUGHS
- A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
- A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
- A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
- A21D2/24—Organic nitrogen compounds
- A21D2/26—Proteins
- A21D2/264—Vegetable proteins
- A21D2/265—Vegetable proteins from cereals, flour, bran
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/06—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
- A23L5/25—Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- General Preparation And Processing Of Foods (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
1490723 Neutralizing gluten J J PHELAN and P F FOTTRELL 29 Oct 1974 [31 Oct 1973 20 March 1974] 46672/74 Heading A5B [Also in Division A2] Preparations, e.g. tablets, for use by people lacking the ability to metabolise gluten in their food comprise (a) a carbohydrase enzyme obtained by fermentation of the fungus Aspergillus niger and (b) a pharmaceutically acceptable carrier. The enzyme may be prepared by (a) growing A. niger in a liquid culture medium (b) removing the mycelium, (c) precipitating the enzyme from the culture medium, (d) dissolving the precipitated enzyme in a buffer solution, (e) passing the solution through an ion-exchange resin, (f) discarding a first run of eluate equal to the bulk volume of the resin and (g) collecting a second run of eluate equal to 1.5 times the volume of the resin.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE196573 | 1973-10-31 | ||
| IE60774 | 1974-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1490723A true GB1490723A (en) | 1977-11-02 |
Family
ID=26318935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB46672/74A Expired GB1490723A (en) | 1973-10-31 | 1974-10-29 | Detoxification of gluten |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE2451388A1 (en) |
| FR (1) | FR2249678B1 (en) |
| GB (1) | GB1490723A (en) |
| NL (1) | NL7414128A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8426145B2 (en) | 2002-11-20 | 2013-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic method for celiac sprue |
| US8524225B2 (en) | 2003-09-23 | 2013-09-03 | Dsm Ip Assets B.V. | Use of proline specific endoproteases to hydrolyse peptides and proteins |
| US8778338B2 (en) | 2007-03-16 | 2014-07-15 | The Board Of Trustees Of The Leland Stanford Junior University | Combination enzyme therapy for digestion of dietary gluten |
| US8796201B2 (en) | 2002-02-14 | 2014-08-05 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
| US8871718B2 (en) | 2005-08-26 | 2014-10-28 | The Board Of Trustees Of The Leland Stanford Junior University | Transglutaminase inhibitors and methods of use thereof |
| US8962545B2 (en) | 2002-02-14 | 2015-02-24 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008090126A1 (en) * | 2007-01-22 | 2008-07-31 | N-Zyme Biotec Gmbh | Beverages for patients with celiac disease and gluten/gliadin-sensitive persons, and method for production thereof |
-
1974
- 1974-10-29 FR FR7436085A patent/FR2249678B1/fr not_active Expired
- 1974-10-29 GB GB46672/74A patent/GB1490723A/en not_active Expired
- 1974-10-29 NL NL7414128A patent/NL7414128A/en unknown
- 1974-10-29 DE DE19742451388 patent/DE2451388A1/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8796201B2 (en) | 2002-02-14 | 2014-08-05 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
| US8962545B2 (en) | 2002-02-14 | 2015-02-24 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
| US8426145B2 (en) | 2002-11-20 | 2013-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic method for celiac sprue |
| US8524225B2 (en) | 2003-09-23 | 2013-09-03 | Dsm Ip Assets B.V. | Use of proline specific endoproteases to hydrolyse peptides and proteins |
| US8871718B2 (en) | 2005-08-26 | 2014-10-28 | The Board Of Trustees Of The Leland Stanford Junior University | Transglutaminase inhibitors and methods of use thereof |
| US8778338B2 (en) | 2007-03-16 | 2014-07-15 | The Board Of Trustees Of The Leland Stanford Junior University | Combination enzyme therapy for digestion of dietary gluten |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2249678A1 (en) | 1975-05-30 |
| NL7414128A (en) | 1975-05-02 |
| DE2451388A1 (en) | 1975-05-07 |
| FR2249678B1 (en) | 1978-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |