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GB1490586A - Apparatus for culturing cells - Google Patents

Apparatus for culturing cells

Info

Publication number
GB1490586A
GB1490586A GB2195975A GB2195975A GB1490586A GB 1490586 A GB1490586 A GB 1490586A GB 2195975 A GB2195975 A GB 2195975A GB 2195975 A GB2195975 A GB 2195975A GB 1490586 A GB1490586 A GB 1490586A
Authority
GB
United Kingdom
Prior art keywords
tube
gas
supply
culture medium
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2195975A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INSTR LABOR Inc
Werfen North America
Original Assignee
Instrumentation Laboratory Co
INSTR LABOR Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/499,515 external-priority patent/US3948732A/en
Application filed by Instrumentation Laboratory Co, INSTR LABOR Inc filed Critical Instrumentation Laboratory Co
Publication of GB1490586A publication Critical patent/GB1490586A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/28—Means for regulation, monitoring, measurement or control, e.g. flow regulation of redox potential

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

In order to culture biological cell cultures on the large scale under controlled conditions, a flat tube (22) composed of gas-permeable, liquid-impermeable material is wound spirally onto a rotatable spool body (88). The interior roughened surface (70) of the tube (22) serves for attachment of the cells. Spacer means (74) keep adjacent windings apart and permit access of gas to the outer surface (76) of the tube (22) over its entire length without, however, hindering the flow of the culture medium through the tube (22). In the cultivation system, the supply and return lines of a large number of tubes (22) are located in a common rotation loop. The latter has a plurality of sensors which control the composition of the gas atmosphere and the supply of fresh culture medium. <IMAGE>
GB2195975A 1974-08-22 1975-05-21 Apparatus for culturing cells Expired GB1490586A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/499,515 US3948732A (en) 1973-05-31 1974-08-22 Cell culture assembly

Publications (1)

Publication Number Publication Date
GB1490586A true GB1490586A (en) 1977-11-02

Family

ID=23985565

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2195975A Expired GB1490586A (en) 1974-08-22 1975-05-21 Apparatus for culturing cells

Country Status (7)

Country Link
JP (1) JPS5813146B2 (en)
CA (1) CA1041931A (en)
CH (1) CH616707A5 (en)
DE (1) DE2537537A1 (en)
FR (1) FR2293493A1 (en)
GB (1) GB1490586A (en)
IT (1) IT1046085B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050522A1 (en) * 1997-05-07 1998-11-12 Baxter International Inc. Method and apparatus for high volume production of viral particles
EP3670643A1 (en) * 2018-12-19 2020-06-24 Asociación Centro de Investigación Cooperativa en Biomateriales - CIC biomaGUNE Support coil

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5913453A (en) * 1982-07-14 1984-01-24 Ricoh Co Ltd Timing information extraction device
US4661455A (en) * 1986-01-16 1987-04-28 Dorr-Oliver Incorporated Membrane cell culturing device
JP2585866B2 (en) * 1990-09-19 1997-02-26 ベリー，エリック・スコット Continuous high density cell culture system
DE4116727C2 (en) 1991-05-17 1995-09-07 Uwe Dr Marx Method and device for the simultaneous cultivation of different mammalian cells
JP6973642B2 (en) * 2018-06-08 2021-12-01 株式会社島津製作所 Cell culture device and cell culture method
JP2021048778A (en) * 2019-09-20 2021-04-01 株式会社島津製作所 Cell recovery method and cell culture apparatus

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1376131A (en) * 1971-02-09 1974-12-04 Nat Res Dev Improvements in and relating to cell culture systems
US3738813A (en) * 1971-06-04 1973-06-12 W Esmond Mass transfer device and method of making same
DE2128744C3 (en) * 1971-06-09 1979-03-29 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Process for the mass cultivation of cells and tissues

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050522A1 (en) * 1997-05-07 1998-11-12 Baxter International Inc. Method and apparatus for high volume production of viral particles
EP3670643A1 (en) * 2018-12-19 2020-06-24 Asociación Centro de Investigación Cooperativa en Biomateriales - CIC biomaGUNE Support coil
WO2020127395A1 (en) * 2018-12-19 2020-06-25 ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOMATERIALES - CIC biomaGUNE Support coil

Also Published As

Publication number Publication date
JPS5813146B2 (en) 1983-03-11
FR2293493B1 (en) 1980-07-04
CA1041931A (en) 1978-11-07
FR2293493A1 (en) 1976-07-02
DE2537537A1 (en) 1976-03-04
CH616707A5 (en) 1980-04-15
IT1046085B (en) 1980-06-30
JPS5141489A (en) 1976-04-07

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee