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GB1489058A - Intermediates for use in preparing cephalosporin analogue - Google Patents

Intermediates for use in preparing cephalosporin analogue

Info

Publication number
GB1489058A
GB1489058A GB119/74A GB11974A GB1489058A GB 1489058 A GB1489058 A GB 1489058A GB 119/74 A GB119/74 A GB 119/74A GB 11974 A GB11974 A GB 11974A GB 1489058 A GB1489058 A GB 1489058A
Authority
GB
United Kingdom
Prior art keywords
group
denotes
intermediates
alpha
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB119/74A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Priority to GB119/74A priority Critical patent/GB1489058A/en
Priority to JP49149286A priority patent/JPS50105691A/ja
Priority to DK689874A priority patent/DK689874A/da
Priority to SE7416388A priority patent/SE7416388L/xx
Priority to BE152078A priority patent/BE824026A/en
Priority to FR7443454A priority patent/FR2262668B1/fr
Priority to NL7417038A priority patent/NL7417038A/en
Priority to CH1740674A priority patent/CH615185A5/en
Priority to AT1040374A priority patent/AT337361B/en
Priority to AU76932/74A priority patent/AU485974B2/en
Priority to DE19742461932 priority patent/DE2461932A1/en
Priority to ZA00750018A priority patent/ZA7518B/en
Publication of GB1489058A publication Critical patent/GB1489058A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Novel compounds, suitable for use as intermediates for the preparation of antibiotically active cephalosporins, of the formula I <IMAGE> wherein Z denotes <2bL>S or <2bL>S->O in the alpha - or ss-configuration; R<1> denotes a free or protected amino group; R<4> denotes hydrogen or a carboxyl protective group; R<5> denotes a hydrogen atom, an acyl group or a protected carboxyl group; and R<8> denotes hydrogen or a 7 alpha -lower alkyl or 7 alpha -lower alkoxy group, are prepared by elimination of hydrogen halide from corresponding compounds which carry a halogenomethyl group, other than the fluoromethyl group, as a substituent in the 2-position.
GB119/74A 1974-01-02 1974-01-02 Intermediates for use in preparing cephalosporin analogue Expired GB1489058A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
GB119/74A GB1489058A (en) 1974-01-02 1974-01-02 Intermediates for use in preparing cephalosporin analogue
JP49149286A JPS50105691A (en) 1974-01-02 1974-12-28
DK689874A DK689874A (en) 1974-01-02 1974-12-30
SE7416388A SE7416388L (en) 1974-01-02 1974-12-30
BE152078A BE824026A (en) 1974-01-02 1974-12-31 NEW INTERMEDIARIES FOR THE PRODUCTION OF COMPOUNDS ANALOGUE TO CEPHALOSPORIN
FR7443454A FR2262668B1 (en) 1974-01-02 1974-12-31
NL7417038A NL7417038A (en) 1974-01-02 1974-12-31 NEW INTERMEDIATE PRODUCTS FOR THE PREPARATION OF OSPORINE ANALOGES.
CH1740674A CH615185A5 (en) 1974-01-02 1974-12-31 Process for the preparation of novel cephalosporin analogues
AT1040374A AT337361B (en) 1974-01-02 1974-12-31 PROCESS FOR MANUFACTURING NEW CEPHALOSPORIN DERIVATIVES
AU76932/74A AU485974B2 (en) 1974-01-02 1974-12-31 Novel intermediates for use in preparing cephalosporin analogues
DE19742461932 DE2461932A1 (en) 1974-01-02 1974-12-31 CEPHALOSPORIN COMPOUNDS
ZA00750018A ZA7518B (en) 1974-01-02 1975-01-02 Chemical compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB119/74A GB1489058A (en) 1974-01-02 1974-01-02 Intermediates for use in preparing cephalosporin analogue

Publications (1)

Publication Number Publication Date
GB1489058A true GB1489058A (en) 1977-10-19

Family

ID=9698752

Family Applications (1)

Application Number Title Priority Date Filing Date
GB119/74A Expired GB1489058A (en) 1974-01-02 1974-01-02 Intermediates for use in preparing cephalosporin analogue

Country Status (11)

Country Link
JP (1) JPS50105691A (en)
AT (1) AT337361B (en)
BE (1) BE824026A (en)
CH (1) CH615185A5 (en)
DE (1) DE2461932A1 (en)
DK (1) DK689874A (en)
FR (1) FR2262668B1 (en)
GB (1) GB1489058A (en)
NL (1) NL7417038A (en)
SE (1) SE7416388L (en)
ZA (1) ZA7518B (en)

Also Published As

Publication number Publication date
SE7416388L (en) 1975-07-03
ZA7518B (en) 1976-01-28
FR2262668B1 (en) 1979-04-20
AU7693274A (en) 1976-07-01
CH615185A5 (en) 1980-01-15
DK689874A (en) 1975-09-01
BE824026A (en) 1975-06-30
AT337361B (en) 1977-06-27
ATA1040374A (en) 1976-10-15
DE2461932A1 (en) 1975-07-03
NL7417038A (en) 1975-07-04
JPS50105691A (en) 1975-08-20
FR2262668A1 (en) 1975-09-26

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee