GB1480175A - Compositions in the form of coated tablets - Google Patents
Compositions in the form of coated tabletsInfo
- Publication number
- GB1480175A GB1480175A GB4127175A GB4127175A GB1480175A GB 1480175 A GB1480175 A GB 1480175A GB 4127175 A GB4127175 A GB 4127175A GB 4127175 A GB4127175 A GB 4127175A GB 1480175 A GB1480175 A GB 1480175A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tablets
- coated tablets
- starch
- maltose
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 abstract 2
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 abstract 2
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 239000002831 pharmacologic agent Substances 0.000 abstract 2
- FSKFPVLPFLJRQB-UHFFFAOYSA-N 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanone Chemical compound C=1C=C(C)C=CC=1C(=O)C(C)CN1CCCCC1 FSKFPVLPFLJRQB-UHFFFAOYSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- 108010004032 Bromelains Proteins 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 229920000623 Cellulose acetate phthalate Polymers 0.000 abstract 1
- 229920002261 Corn starch Polymers 0.000 abstract 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 235000021314 Palmitic acid Nutrition 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 240000006394 Sorghum bicolor Species 0.000 abstract 1
- 235000021355 Stearic acid Nutrition 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 235000019835 bromelain Nutrition 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- 239000001175 calcium sulphate Substances 0.000 abstract 1
- 235000011132 calcium sulphate Nutrition 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 229940081734 cellulose acetate phthalate Drugs 0.000 abstract 1
- 239000008120 corn starch Substances 0.000 abstract 1
- 238000007907 direct compression Methods 0.000 abstract 1
- 239000007884 disintegrant Substances 0.000 abstract 1
- 239000001341 hydroxy propyl starch Substances 0.000 abstract 1
- 235000013828 hydroxypropyl starch Nutrition 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 abstract 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229920001592 potato starch Polymers 0.000 abstract 1
- 229940116317 potato starch Drugs 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 235000010356 sorbitol Nutrition 0.000 abstract 1
- 239000008117 stearic acid Substances 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
1480175 Coated tablets NIPPON KAYAKU KK and HAYASHIBARA BIOCHEMICAL LABORATORIES INC 8 Oct 1975 [8 Oct 1974] 41271/75 Heading A5B Pharmaceutical preparations in the form of coated tablets prepared by the direct compression method comprise a pharmacologically active ingredient e.g. 2, 4'-dimethyl-3- piperidinopropiophenone or bromelain and maltose are prepared by mixing a pharmacologically active ingredient with maltose, directly compressing the mixture into tablets and coating the tablets. The coating may be sugar or cellulose acetate phthalate. The preparation may further comprise a lubricant e.g. talc, silicon dioxide powder, magnesium stearate, stearic acid or palmitic acid; an adjuvant such as crystalline lactose, mannitol, sorbitol, calcium sulphate or anhydrous calcium phosphate; and/or a disintegrant e.g. corn starch, potato-starch, calcium carboxymethyl cellulose or hydroxy propyl starch.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11521374A JPS5154918A (en) | 1974-10-08 | 1974-10-08 | Jozaino seizoho |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1480175A true GB1480175A (en) | 1977-07-20 |
Family
ID=14657155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4127175A Expired GB1480175A (en) | 1974-10-08 | 1975-10-08 | Compositions in the form of coated tablets |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5154918A (en) |
| DE (1) | DE2544881A1 (en) |
| FR (1) | FR2287215A1 (en) |
| GB (1) | GB1480175A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2123289A (en) * | 1982-06-07 | 1984-02-01 | Boehringer Ingelheim Int | Method of stabalising pharmaceutical multi-layered tablets |
| US5556639A (en) * | 1991-01-30 | 1996-09-17 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| US5629016A (en) * | 1991-01-30 | 1997-05-13 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| US5698226A (en) * | 1993-07-13 | 1997-12-16 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| US5698221A (en) * | 1992-07-27 | 1997-12-16 | Patel; Suryakant Dahyabhai | Water-dispersible tablets |
| WO2000059508A1 (en) * | 1999-04-01 | 2000-10-12 | Sanochemia Pharmazeutika Ag | Tolperison-containing, pharmaceutical preparation for oral administration |
| EP1161941A4 (en) * | 1999-03-15 | 2002-08-28 | Kaken Pharma Co Ltd | FAST DELITING TABLETS AND MANUFACTURING METHOD |
| WO2009013552A1 (en) * | 2007-07-23 | 2009-01-29 | Richter Gedeon Nyrt. | Controlled release pharmaceutical composition of tolperison hydrochloride |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52133823A (en) * | 1976-05-04 | 1977-11-09 | Kurogane Zoukeiki Kk | Molding machine |
| WO1989006643A1 (en) * | 1988-01-22 | 1989-07-27 | Kharkovsky Nauchno-Issledovatelsky Institut Endokr | UNDECYLIC ETHER n-CHLOROPHENOXYISOBUTYRIC ACID AND A PHARMACEUTICAL PREPARATION FOR TREATING HYPERLIPEMIA BASED ON IT |
| KR20010033938A (en) * | 1998-01-14 | 2001-04-25 | 스즈키 다다시 | Disintegrating agent |
| CN114431477A (en) * | 2022-03-01 | 2022-05-06 | 广州市沐家健康产业有限公司 | A kind of probiotics tablet preparation and its preparation method and application |
| CN115956635A (en) * | 2022-12-26 | 2023-04-14 | 广西商大科技股份有限公司 | Weaned piglet flaky creep feed and preparation method thereof |
| WO2025115792A1 (en) * | 2023-11-29 | 2025-06-05 | 長瀬産業株式会社 | Composition and solid molded body |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3627583A (en) * | 1969-04-29 | 1971-12-14 | Sucrest Corp | Direct compression vehicles |
-
1974
- 1974-10-08 JP JP11521374A patent/JPS5154918A/en active Granted
-
1975
- 1975-10-07 DE DE19752544881 patent/DE2544881A1/en active Pending
- 1975-10-08 GB GB4127175A patent/GB1480175A/en not_active Expired
- 1975-10-08 FR FR7530764A patent/FR2287215A1/en active Granted
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2123289A (en) * | 1982-06-07 | 1984-02-01 | Boehringer Ingelheim Int | Method of stabalising pharmaceutical multi-layered tablets |
| US5556639A (en) * | 1991-01-30 | 1996-09-17 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| US5629016A (en) * | 1991-01-30 | 1997-05-13 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| US5660860A (en) * | 1991-01-30 | 1997-08-26 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| US5698221A (en) * | 1992-07-27 | 1997-12-16 | Patel; Suryakant Dahyabhai | Water-dispersible tablets |
| US5698226A (en) * | 1993-07-13 | 1997-12-16 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| EP1161941A4 (en) * | 1999-03-15 | 2002-08-28 | Kaken Pharma Co Ltd | FAST DELITING TABLETS AND MANUFACTURING METHOD |
| WO2000059508A1 (en) * | 1999-04-01 | 2000-10-12 | Sanochemia Pharmazeutika Ag | Tolperison-containing, pharmaceutical preparation for oral administration |
| US6500455B1 (en) | 1999-04-01 | 2002-12-31 | Sanochemia Pharmazeutika | Tolperison-containing, pharmaceutical preparation for oral administration |
| WO2009013552A1 (en) * | 2007-07-23 | 2009-01-29 | Richter Gedeon Nyrt. | Controlled release pharmaceutical composition of tolperison hydrochloride |
| EA018885B1 (en) * | 2007-07-23 | 2013-11-29 | Рихтер Гедеон Нирт. | Controlled release pharmaceutical composition of tolperison hydrochloride |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2287215B1 (en) | 1980-04-25 |
| JPS5154918A (en) | 1976-05-14 |
| FR2287215A1 (en) | 1976-05-07 |
| JPS5436644B2 (en) | 1979-11-10 |
| DE2544881A1 (en) | 1976-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |