GB1479909A - 4-oxo-2-imidazolidinylideneureas - Google Patents
4-oxo-2-imidazolidinylideneureasInfo
- Publication number
- GB1479909A GB1479909A GB45246/74A GB4524674A GB1479909A GB 1479909 A GB1479909 A GB 1479909A GB 45246/74 A GB45246/74 A GB 45246/74A GB 4524674 A GB4524674 A GB 4524674A GB 1479909 A GB1479909 A GB 1479909A
- Authority
- GB
- United Kingdom
- Prior art keywords
- denotes
- hydrogen atom
- radical
- compounds
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000005840 aryl radicals Chemical class 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- -1 alkyl radical Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- TYKJILJOXAHUFO-UHFFFAOYSA-N 2-amino-1,4-dihydroimidazol-5-one Chemical class NC1=NC(=O)CN1 TYKJILJOXAHUFO-UHFFFAOYSA-N 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 238000013016 damping Methods 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel 4-oxo-2-imidazolidinylidene-ureas of the formula <IMAGE> wherein R1 denotes a hydrogen atom or a lower alkyl radical, R2 denotes a hydrogen atom or a lower alkyl radical, R3 denotes a hydrogen atom or an aryl radical, R4 denotes a hydrogen atom, an aryl radical or an arylalkyl radical and Ar denotes an aryl radical, with the exception of compounds in which R3 and R4 represent 2,6-disubstituted aryl radicals, are prepared. These compounds are obtained by reacting a correspondingly substituted 2-iminoimidazolidin-4-one with an arylisocyanate in an inert aprotic organic solvent. The novel compounds exert an inhibiting action on the secretion of gastric juices and a damping (suppressing) action on the central nervous system.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40802273A | 1973-10-19 | 1973-10-19 | |
| US50879574A | 1974-09-23 | 1974-09-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1479909A true GB1479909A (en) | 1977-07-13 |
Family
ID=27020109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB45246/74A Expired GB1479909A (en) | 1973-10-19 | 1974-10-18 | 4-oxo-2-imidazolidinylideneureas |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5077367A (en) |
| AR (1) | AR210320A1 (en) |
| AT (1) | AT348536B (en) |
| BE (1) | BE821099A (en) |
| CA (1) | CA1043339A (en) |
| CH (1) | CH614198A5 (en) |
| DD (1) | DD114079A5 (en) |
| DE (1) | DE2448869A1 (en) |
| DK (1) | DK548874A (en) |
| ES (1) | ES431153A1 (en) |
| FI (1) | FI59993C (en) |
| FR (1) | FR2248042B1 (en) |
| GB (1) | GB1479909A (en) |
| HU (1) | HU170857B (en) |
| IE (1) | IE40067B1 (en) |
| IL (1) | IL45865A (en) |
| IN (1) | IN139447B (en) |
| NL (1) | NL7413718A (en) |
| NO (1) | NO141162C (en) |
| RO (1) | RO64926A (en) |
| SE (1) | SE414173B (en) |
| YU (1) | YU36932B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI800559A7 (en) * | 1979-03-14 | 1981-01-01 | F Hoffmann La Roche & Co | Urea derivatives. |
| US4265900A (en) * | 1979-10-29 | 1981-05-05 | Mcneilab, Inc. | N-Aryl-N'-imidazol-2-ylureas |
| WO2005058311A1 (en) * | 2003-12-15 | 2005-06-30 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| WO2014127042A1 (en) | 2013-02-12 | 2014-08-21 | Buck Institute For Research On Aging | Hydantoins that modulate bace-mediated app processing |
-
1974
- 1974-10-14 DE DE19742448869 patent/DE2448869A1/en not_active Withdrawn
- 1974-10-15 SE SE7412959A patent/SE414173B/en unknown
- 1974-10-15 BE BE149558A patent/BE821099A/en unknown
- 1974-10-16 AR AR256117A patent/AR210320A1/en active
- 1974-10-17 CH CH1395174A patent/CH614198A5/en not_active IP Right Cessation
- 1974-10-17 IL IL45865A patent/IL45865A/en unknown
- 1974-10-17 RO RO197480253A patent/RO64926A/en unknown
- 1974-10-18 DK DK548874A patent/DK548874A/da not_active Application Discontinuation
- 1974-10-18 YU YU2797/74A patent/YU36932B/en unknown
- 1974-10-18 FI FI3065/74A patent/FI59993C/en active
- 1974-10-18 FR FR7435155A patent/FR2248042B1/fr not_active Expired
- 1974-10-18 JP JP49119494A patent/JPS5077367A/ja active Pending
- 1974-10-18 NO NO743771A patent/NO141162C/en unknown
- 1974-10-18 AT AT840974A patent/AT348536B/en not_active IP Right Cessation
- 1974-10-18 GB GB45246/74A patent/GB1479909A/en not_active Expired
- 1974-10-18 ES ES431153A patent/ES431153A1/en not_active Expired
- 1974-10-18 NL NL7413718A patent/NL7413718A/en not_active Application Discontinuation
- 1974-10-18 CA CA211,775A patent/CA1043339A/en not_active Expired
- 1974-10-18 IE IE2146/74A patent/IE40067B1/en unknown
- 1974-10-18 HU HU74ME00001786A patent/HU170857B/en unknown
- 1974-10-21 DD DD181808A patent/DD114079A5/xx unknown
- 1974-11-07 IN IN2451/CAL/74A patent/IN139447B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5077367A (en) | 1975-06-24 |
| ATA840974A (en) | 1978-07-15 |
| FI59993C (en) | 1981-11-10 |
| AU7443874A (en) | 1976-04-29 |
| SE414173B (en) | 1980-07-14 |
| NO141162B (en) | 1979-10-15 |
| AT348536B (en) | 1979-02-26 |
| SE7412959L (en) | 1975-04-21 |
| FI59993B (en) | 1981-07-31 |
| NL7413718A (en) | 1975-04-22 |
| DD114079A5 (en) | 1975-07-12 |
| NO141162C (en) | 1980-01-23 |
| HU170857B (en) | 1977-09-28 |
| RO64926A (en) | 1980-01-15 |
| FR2248042B1 (en) | 1978-07-21 |
| IE40067B1 (en) | 1979-02-28 |
| FR2248042A1 (en) | 1975-05-16 |
| AR210320A1 (en) | 1977-07-29 |
| DK548874A (en) | 1975-07-07 |
| CH614198A5 (en) | 1979-11-15 |
| IN139447B (en) | 1976-06-19 |
| IL45865A (en) | 1978-01-31 |
| FI306574A7 (en) | 1975-04-20 |
| YU36932B (en) | 1984-08-31 |
| BE821099A (en) | 1975-04-15 |
| CA1043339A (en) | 1978-11-28 |
| DE2448869A1 (en) | 1975-09-04 |
| IL45865A0 (en) | 1975-02-10 |
| YU279774A (en) | 1982-06-18 |
| IE40067L (en) | 1975-04-19 |
| ES431153A1 (en) | 1977-02-01 |
| NO743771L (en) | 1975-05-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE821872L (en) | Amine derivatives. | |
| ES8300699A1 (en) | Heterocyclic compounds | |
| GB1499485A (en) | Thiocarbamide derivatives and process for their preparation | |
| GB1479909A (en) | 4-oxo-2-imidazolidinylideneureas | |
| ES464469A1 (en) | Stabilisers for synthetic polymers and a process for their preparation | |
| ES477852A1 (en) | Amides derived from carboxyl-5 pyrimidines | |
| AU538429B2 (en) | Polytriazinylamines used as stabilizers for synthetic polymers | |
| ES429870A1 (en) | (2-6-Oxymethylene) morpholino (4,3a) benzimidazoles | |
| ES427291A1 (en) | 17-Nor-6-methyl-steroids | |
| ES2002663A6 (en) | Substituted diazaoxaspirodecanes, their preparation and their use as stabilizers for polymers. | |
| FR2378062A1 (en) | STABILIZATION OF THERMOPLASTIC MATERIALS USING TRIAZA-ADAMANTYL-UREES | |
| DE3264928D1 (en) | Process for producing brominated 1,3-dioxolen-2-ones | |
| IE42390L (en) | Substituted indoles. | |
| ES429871A1 (en) | 1,3-Benzodioxol derivatives | |
| ES8200688A1 (en) | Penicillin compounds | |
| ES451067A1 (en) | Psychotropic 2-trifluoromethyl-10-{8 3-(3-hydroxy-pyrrolidino)-propyl{9 -phenothiazine compounds | |
| AU561575B2 (en) | Substituted benzyl-cycloalkenylurea derivatives | |
| ES428297A1 (en) | Triazolyl ethenyl phenylene derivatives | |
| HUT43020A (en) | Process for preparing dialkoxy-ketones | |
| IE41394B1 (en) | Substituted benimidazoles | |
| FR2359152A1 (en) | PHOSPHITES OF POLYALCOOLS THAT CAN BE USED FOR THE STABILIZATION OF POLYMERIC MATERIALS | |
| ES451292A1 (en) | A procedure for the preparation of tienotiacin derivatives. (Machine-translation by Google Translate, not legally binding) | |
| CS8103958A2 (en) | Zpusob vyroby uhlovodikoveho roztoku alkylsodne slouceniny | |
| ES442805A1 (en) | 1-thiadiazolyl-5-acylimidazolidinones | |
| GB1509034A (en) | Herbicides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |