GB1478009A - Pharmaceutical compositions - Google Patents
Pharmaceutical compositionsInfo
- Publication number
- GB1478009A GB1478009A GB1575873A GB1575873A GB1478009A GB 1478009 A GB1478009 A GB 1478009A GB 1575873 A GB1575873 A GB 1575873A GB 1575873 A GB1575873 A GB 1575873A GB 1478009 A GB1478009 A GB 1478009A
- Authority
- GB
- United Kingdom
- Prior art keywords
- active agent
- water
- wax
- surface active
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 239000002904 solvent Substances 0.000 abstract 3
- 239000004094 surface-active agent Substances 0.000 abstract 3
- 239000001993 wax Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- KMZHZAAOEWVPSE-UHFFFAOYSA-N 2,3-dihydroxypropyl acetate Chemical compound CC(=O)OCC(O)CO KMZHZAAOEWVPSE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 abstract 1
- 239000004141 Sodium laurylsulphate Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 235000013871 bee wax Nutrition 0.000 abstract 1
- 239000012166 beeswax Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 abstract 1
- YHAIUSTWZPMYGG-UHFFFAOYSA-L disodium;2,2-dioctyl-3-sulfobutanedioate Chemical compound [Na+].[Na+].CCCCCCCCC(C([O-])=O)(C(C([O-])=O)S(O)(=O)=O)CCCCCCCC YHAIUSTWZPMYGG-UHFFFAOYSA-L 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002191 fatty alcohols Chemical class 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- 239000008250 pharmaceutical cream Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229940051841 polyoxyethylene ether Drugs 0.000 abstract 1
- 229920000056 polyoxyethylene ether Polymers 0.000 abstract 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 abstract 1
- 150000004671 saturated fatty acids Chemical class 0.000 abstract 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1478009 Pharmaceutical compositions GLAXO LABORATORIES Ltd 11 June 1974 [2 April 1973] 15758/73 Heading A5B Substantially oil-free pharmaceutical creams comprise (a) a topically active anti-inflammatory steroid/except 21-chloro-9α-fluoro-#<SP>4</SP>- pregnene-11#, 16α, 17α-triol-3, 20-dione-16, 17-acetonide) in (b) a vehicle comprising a dispersion of a hydrophobic wax in an aqueous phase comprising water, a surface active agent, and a water-miscible hydroxylic solvent, the wax, water, solvent and surface active agent being present in amounts of 5 to 30%, 7 to 75%, 10 to 80% and 0.1 to 10% respectively, based on the weight of the composition. The steroid may be corticosteroid. The hydroxylic solvent may be a propanediol, a dipropylene glycol, a liquid polyethylene glycol or glycerol. The wax may be a waxy triglyceride, a waxy fatty alcohol, a saturated fatty acid, an acetoglyceride or beeswax. The surface active agent may be a polyoxyethylene ether or ester, sodium lauryl sulphate or sodium dioctyl sulphosuccinate. The compositions may contain other drugs such as antibodies, local anaesthetics, bactericides or antifungal compounds.
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1575873A GB1478009A (en) | 1973-04-02 | 1973-04-02 | Pharmaceutical compositions |
| DE19732347243 DE2347243A1 (en) | 1973-04-02 | 1973-09-19 | PHARMACEUTICAL COMPOSITIONS |
| AU67246/74A AU492729B2 (en) | 1973-04-02 | 1974-03-28 | Pharmaceutical compositions |
| IE00703/74A IE39113B1 (en) | 1973-04-02 | 1974-04-01 | Pharmaceutical compositions |
| BE142726A BE813153A (en) | 1973-04-02 | 1974-04-01 | COMPOSITIONS OF OIL-FREE PHARMACEUTICAL CREAMS |
| ZA00742064A ZA742064B (en) | 1973-04-02 | 1974-04-01 | Pharmaceutical compositions |
| DK179474A DK144358C (en) | 1973-04-02 | 1974-04-01 | CREME CONTAINING ONE OR MORE TOPICALLY ACTIVE MEDICINES IN A CARRIER AND THEIR MANUFACTURING PRODUCTS |
| CA196,544A CA1045974A (en) | 1973-04-02 | 1974-04-01 | Oil-free pharmaceutical cream |
| FR7411572A FR2222998B1 (en) | 1973-04-02 | 1974-04-01 | |
| LU69751A LU69751A1 (en) | 1973-04-02 | 1974-04-01 | |
| NL7404378A NL7404378A (en) | 1973-04-02 | 1974-04-01 | |
| JP49035716A JPS589081B2 (en) | 1973-04-02 | 1974-04-01 | Vehicle composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1575873A GB1478009A (en) | 1973-04-02 | 1973-04-02 | Pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1478009A true GB1478009A (en) | 1977-06-29 |
Family
ID=10064952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1575873A Expired GB1478009A (en) | 1973-04-02 | 1973-04-02 | Pharmaceutical compositions |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS589081B2 (en) |
| BE (1) | BE813153A (en) |
| CA (1) | CA1045974A (en) |
| DE (1) | DE2347243A1 (en) |
| DK (1) | DK144358C (en) |
| FR (1) | FR2222998B1 (en) |
| GB (1) | GB1478009A (en) |
| IE (1) | IE39113B1 (en) |
| LU (1) | LU69751A1 (en) |
| NL (1) | NL7404378A (en) |
| ZA (1) | ZA742064B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2123292A (en) * | 1982-07-07 | 1984-02-01 | Schering Ag | Topical corticoid-containing preparations |
| US4963555A (en) * | 1980-07-18 | 1990-10-16 | Burroughs Wellcome Co. | Formulations of heterocyclic compounds |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8004580L (en) * | 1980-06-19 | 1981-12-20 | Draco Ab | PHARMACEUTICAL PREPARATION |
| GB2080106B (en) * | 1980-07-18 | 1984-03-07 | Weelcome Foundation Ltd | Acyclovin preparations |
| US4868169A (en) * | 1987-11-13 | 1989-09-19 | E. R. Squibb & Sons, Inc. | Steroid cream formulation |
| LU87457A1 (en) * | 1989-02-24 | 1990-09-19 | Oreal | USE, AS A COSMETIC COMPOSITION FOR HAIR, OF A WAX MICRODISPERSION, AND METHOD FOR TREATING HAIR WITH SUCH A COMPOSITION |
| US8491875B2 (en) * | 2010-08-18 | 2013-07-23 | Kao Corporation | Hair volumizing compositions |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB765600A (en) * | 1954-01-15 | 1957-01-09 | Drug Houses Of Australia Ltd | Salves for veterinary use |
| GB903407A (en) * | 1958-07-25 | 1962-08-15 | Upjohn Co | Improvements in or relating to antibacterial antiperspirant compositions |
| DE1198011B (en) * | 1962-08-04 | 1965-08-05 | Iwao Kawakami | Skin care products |
| BR6789910D0 (en) * | 1966-10-17 | 1973-05-17 | Fmc Corp | PROCESS TO PREPARE EDIBLE CONTAINING MICRO CRYSTALLINE COLLAGEN |
-
1973
- 1973-04-02 GB GB1575873A patent/GB1478009A/en not_active Expired
- 1973-09-19 DE DE19732347243 patent/DE2347243A1/en active Pending
-
1974
- 1974-04-01 LU LU69751A patent/LU69751A1/xx unknown
- 1974-04-01 ZA ZA00742064A patent/ZA742064B/en unknown
- 1974-04-01 NL NL7404378A patent/NL7404378A/xx unknown
- 1974-04-01 JP JP49035716A patent/JPS589081B2/en not_active Expired
- 1974-04-01 IE IE00703/74A patent/IE39113B1/en unknown
- 1974-04-01 DK DK179474A patent/DK144358C/en not_active IP Right Cessation
- 1974-04-01 CA CA196,544A patent/CA1045974A/en not_active Expired
- 1974-04-01 BE BE142726A patent/BE813153A/en not_active IP Right Cessation
- 1974-04-01 FR FR7411572A patent/FR2222998B1/fr not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963555A (en) * | 1980-07-18 | 1990-10-16 | Burroughs Wellcome Co. | Formulations of heterocyclic compounds |
| GB2123292A (en) * | 1982-07-07 | 1984-02-01 | Schering Ag | Topical corticoid-containing preparations |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS589081B2 (en) | 1983-02-18 |
| DK144358C (en) | 1984-04-09 |
| DK144358B (en) | 1982-03-01 |
| CA1045974A (en) | 1979-01-09 |
| BE813153A (en) | 1974-10-01 |
| ZA742064B (en) | 1975-03-26 |
| IE39113L (en) | 1974-10-02 |
| JPS5058218A (en) | 1975-05-21 |
| AU6724674A (en) | 1975-10-02 |
| DE2347243A1 (en) | 1974-10-10 |
| IE39113B1 (en) | 1978-08-02 |
| LU69751A1 (en) | 1974-07-17 |
| FR2222998A1 (en) | 1974-10-25 |
| FR2222998B1 (en) | 1977-11-04 |
| NL7404378A (en) | 1974-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |