GB1465665A - Topical composition - Google Patents
Topical compositionInfo
- Publication number
- GB1465665A GB1465665A GB3757775A GB3757775A GB1465665A GB 1465665 A GB1465665 A GB 1465665A GB 3757775 A GB3757775 A GB 3757775A GB 3757775 A GB3757775 A GB 3757775A GB 1465665 A GB1465665 A GB 1465665A
- Authority
- GB
- United Kingdom
- Prior art keywords
- composition
- alcohol
- aqueous
- menthol
- camphor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- 230000000699 topical effect Effects 0.000 title abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 6
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 3
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract 2
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 abstract 2
- 241000723346 Cinnamomum camphora Species 0.000 abstract 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- -1 antiseptics Substances 0.000 abstract 2
- 229960000846 camphor Drugs 0.000 abstract 2
- 229930008380 camphor Natural products 0.000 abstract 2
- 229940041616 menthol Drugs 0.000 abstract 2
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 229940064004 antiseptic throat preparations Drugs 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000011928 denatured alcohol Substances 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 abstract 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 abstract 1
- LVTYICIALWPMFW-UHFFFAOYSA-N diisopropanolamine Chemical compound CC(O)CNCC(C)O LVTYICIALWPMFW-UHFFFAOYSA-N 0.000 abstract 1
- 229940043276 diisopropanolamine Drugs 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
Abstract
1465665 Topical composition TOKO YAKUHIN KOGYO KK 12 Sept 1975 [7 Oct 1974] 37577/75 Heading A5B A topical composition of viscosity 3000- 40000 centipoise at 30‹C comprises a carboxyvinyl polymer, alcohol, menthol and/or camphor in an aqueous medium, the composition having been adjusted to a pH of about 7 with an organic amine. The preparation entails adding an aqueous polymer solution to aqueous alcohol, menthol and/or camphor followed by adjusting the resulting mixture to a pH of about 7 with the amine e.g. triethanolamine, triethylamine, diisopropanolamine or diethylamine. Preferably the polymer comprises 0.15- 1.0 wt. percent of the composition. Other active ingredients may be included in the composition e.g. antiseptics, disinfectants, local anaesthetics, vasodilators or antihistamines. Ethanol or denatured alcohol are conveniently utilised as the alcohol components, preferably present in an amount of from 20-90 wt. percent of the composition. Suitable polymers may be selected from "Carkopol" (Registered Trade Mark) 934, 940 and 941.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11580474A JPS5144618A (en) | 1974-10-07 | 1974-10-07 | Kyokushoyozaino seizoho |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1465665A true GB1465665A (en) | 1977-02-23 |
Family
ID=14671486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3757775A Expired GB1465665A (en) | 1974-10-07 | 1975-09-12 | Topical composition |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS5144618A (en) |
| GB (1) | GB1465665A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4472372A (en) * | 1979-08-14 | 1984-09-18 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing chlorpheniramine maleate |
| EP0137173A3 (en) * | 1983-08-11 | 1986-01-02 | Beecham Group Plc | Deodorant formulations |
| EP0223681A1 (en) * | 1985-10-28 | 1987-05-27 | Calgon Corporation | Alcohol-based antimicrobial compositions and method for enhancing their efficacity |
| EP0225848A3 (en) * | 1985-12-03 | 1988-01-27 | Warner-Lambert Company | Analgesic stick composition |
| EP0268164A3 (en) * | 1986-11-10 | 1989-03-15 | The B.F. Goodrich Company | Stable and quick-breaking topical skin compositions |
| EP0320254A1 (en) * | 1987-12-09 | 1989-06-14 | Thames Pharmacal Co.Inc. | Aqueous gels containing topical medicaments |
| US4940579A (en) * | 1988-12-27 | 1990-07-10 | Minnesota Mining And Manufacturing Company | Topical application of medicament in a binder |
| EP0391342A1 (en) * | 1989-04-05 | 1990-10-10 | Toko Yakuhin Kogyo Kabushiki Kaisha | Spray gel base and spray gel preparation using thereof |
| US5098717A (en) * | 1987-12-09 | 1992-03-24 | Thames Pharmacal Co., Inc. | Method of treatment for pruritus |
| US5215739A (en) * | 1989-04-05 | 1993-06-01 | Toko Yakuhin Kogyo Kabushiki Kaisha | Spray gel base and spray gel preparation using thereof |
| EP0672422A1 (en) * | 1994-02-05 | 1995-09-20 | Il-Dong Pharm. Co., Ltd. | Antiinflammatory and analgesic transdermal gel |
| WO2020223093A1 (en) * | 2019-04-30 | 2020-11-05 | Bayer Healthcare Llc | Topical analgesic gel compositions |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57206610A (en) * | 1981-06-12 | 1982-12-18 | Lion Corp | Anti-inflammatory analgesic solution for external use |
| WO1984004681A1 (en) * | 1983-05-25 | 1984-12-06 | Alcon Lab Inc | Ophthalmic solution |
| WO1984004680A1 (en) * | 1983-05-25 | 1984-12-06 | Alcon Lab Inc | Ophthalmic gel |
| JP7422261B1 (en) * | 2023-07-31 | 2024-01-25 | ロート製薬株式会社 | Emulsified external composition |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1268461A (en) * | 1959-05-21 | 1961-08-04 | Cosmetic product and its production process |
-
1974
- 1974-10-07 JP JP11580474A patent/JPS5144618A/en active Granted
-
1975
- 1975-09-12 GB GB3757775A patent/GB1465665A/en not_active Expired
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4492685A (en) * | 1979-08-14 | 1985-01-08 | Key Pharmaceuticals, Inc. | Protective skin matrix |
| US4472372A (en) * | 1979-08-14 | 1984-09-18 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing chlorpheniramine maleate |
| EP0137173A3 (en) * | 1983-08-11 | 1986-01-02 | Beecham Group Plc | Deodorant formulations |
| EP0223681A1 (en) * | 1985-10-28 | 1987-05-27 | Calgon Corporation | Alcohol-based antimicrobial compositions and method for enhancing their efficacity |
| EP0225848A3 (en) * | 1985-12-03 | 1988-01-27 | Warner-Lambert Company | Analgesic stick composition |
| EP0268164A3 (en) * | 1986-11-10 | 1989-03-15 | The B.F. Goodrich Company | Stable and quick-breaking topical skin compositions |
| US5098717A (en) * | 1987-12-09 | 1992-03-24 | Thames Pharmacal Co., Inc. | Method of treatment for pruritus |
| EP0320254A1 (en) * | 1987-12-09 | 1989-06-14 | Thames Pharmacal Co.Inc. | Aqueous gels containing topical medicaments |
| US5013545A (en) * | 1987-12-09 | 1991-05-07 | Thames Pharmacal Co., Inc. | Aqueous gels containing topical medicaments |
| US4940579A (en) * | 1988-12-27 | 1990-07-10 | Minnesota Mining And Manufacturing Company | Topical application of medicament in a binder |
| EP0391342A1 (en) * | 1989-04-05 | 1990-10-10 | Toko Yakuhin Kogyo Kabushiki Kaisha | Spray gel base and spray gel preparation using thereof |
| US5158761A (en) * | 1989-04-05 | 1992-10-27 | Toko Yakuhin Kogyo Kabushiki Kaisha | Spray gel base and spray gel preparation using thereof |
| US5215739A (en) * | 1989-04-05 | 1993-06-01 | Toko Yakuhin Kogyo Kabushiki Kaisha | Spray gel base and spray gel preparation using thereof |
| EP0672422A1 (en) * | 1994-02-05 | 1995-09-20 | Il-Dong Pharm. Co., Ltd. | Antiinflammatory and analgesic transdermal gel |
| WO2020223093A1 (en) * | 2019-04-30 | 2020-11-05 | Bayer Healthcare Llc | Topical analgesic gel compositions |
| US11617727B2 (en) * | 2019-04-30 | 2023-04-04 | Bayer Healthcare Llc | Topical analgesic gel compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5144618A (en) | 1976-04-16 |
| JPS5418329B2 (en) | 1979-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19950911 |