GB1465321A - Production having cytostatic activity and a process for its preparation - Google Patents
Production having cytostatic activity and a process for its preparationInfo
- Publication number
- GB1465321A GB1465321A GB1650674A GB1650674A GB1465321A GB 1465321 A GB1465321 A GB 1465321A GB 1650674 A GB1650674 A GB 1650674A GB 1650674 A GB1650674 A GB 1650674A GB 1465321 A GB1465321 A GB 1465321A
- Authority
- GB
- United Kingdom
- Prior art keywords
- water
- solvent
- kigelia
- april
- extracted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
1465321 Medicines comprising plant extracts H OTTO 16 April 1974 [17 April 1973] 16506/74 Heading A5B A water-soluble material having cytostatic activity is obtained by extracting plants of the Kigelia species, especially the fruit, using water-as a or the solvent. Preferably the comminuted and optionally dried vegetable material of a Kigelia plant is first extracted with a non-polar or slightly polar solvent, e.g. a hydrocarbon, halogenated hydrocarbon, ether, ketone alcohol, pyridine or mixtures of these, and the residue is extracted with at least one solvent comprising water. The solvent comprising water may be water itself or water mixed with, for example, liquid ammonia, a lower alkanoic acid, dimethyl sulphoxide, dimethyl formamide an alcohol or a ketone. Finally, the water-soluble product may be isolated by lyophilization. The approximate analysis of the dried product is carbon (34.7%), hydrogen (5.1%), phosphorus (1.9%), nitrogen (0.4%), chlorine (0.1%), water (3.8%) and ash (20.1%), and it has an I/R spectrum as shown in the drawing. It may be incorporated into pharmaceutical compositions for oral, parenteral, rectal and topical administration containing conventional carriers and excipients.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH549173 | 1973-04-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1465321A true GB1465321A (en) | 1977-02-23 |
Family
ID=4294471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1650674A Expired GB1465321A (en) | 1973-04-17 | 1974-04-16 | Production having cytostatic activity and a process for its preparation |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS505516A (en) |
| BE (1) | BE813741A (en) |
| DE (1) | DE2417071A1 (en) |
| FR (1) | FR2226186A1 (en) |
| GB (1) | GB1465321A (en) |
| NL (1) | NL7405198A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2759910A1 (en) * | 1997-02-24 | 1998-08-28 | Greentech Sa | Cosmetic and dermo-pharmaceutical use of extracts of Kigelia africana |
| WO2006002443A1 (en) * | 2004-06-24 | 2006-01-05 | Rudolf Karl Schleipfer | Pharmaceutical or cosmetic preparation based on kigelia africana |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2780885B1 (en) * | 1998-07-10 | 2001-10-12 | C3D Sarl | NEW HIGH VISCOSITY COSMETIC COMPOSITIONS FOR APPLICATION ON THE SKIN |
-
1974
- 1974-04-08 DE DE2417071A patent/DE2417071A1/en active Pending
- 1974-04-12 FR FR7412975A patent/FR2226186A1/fr not_active Withdrawn
- 1974-04-16 BE BE143217A patent/BE813741A/en unknown
- 1974-04-16 JP JP49041788A patent/JPS505516A/ja active Pending
- 1974-04-16 GB GB1650674A patent/GB1465321A/en not_active Expired
- 1974-04-17 NL NL7405198A patent/NL7405198A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2759910A1 (en) * | 1997-02-24 | 1998-08-28 | Greentech Sa | Cosmetic and dermo-pharmaceutical use of extracts of Kigelia africana |
| WO2006002443A1 (en) * | 2004-06-24 | 2006-01-05 | Rudolf Karl Schleipfer | Pharmaceutical or cosmetic preparation based on kigelia africana |
Also Published As
| Publication number | Publication date |
|---|---|
| BE813741A (en) | 1974-10-16 |
| JPS505516A (en) | 1975-01-21 |
| NL7405198A (en) | 1974-10-21 |
| FR2226186A1 (en) | 1974-11-15 |
| DE2417071A1 (en) | 1974-11-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |