GB1461300A - Dihydroapovincaminic acid amides - Google Patents
Dihydroapovincaminic acid amidesInfo
- Publication number
- GB1461300A GB1461300A GB2794074A GB2794074A GB1461300A GB 1461300 A GB1461300 A GB 1461300A GB 2794074 A GB2794074 A GB 2794074A GB 2794074 A GB2794074 A GB 2794074A GB 1461300 A GB1461300 A GB 1461300A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- dihydroapovincaminic
- unsaturated
- acid amides
- aliphatic hydrocarbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1461300 Dihydroapovincaminic acid amides SYNTHELABO 24 June 1974 27940/74 Heading C2C Novel compounds of the Formula I wherein B is -NR 1 R 2 in which R 1 is hydrogen C 1-4 alkyl or an unsaturated C 2-4 aliphatic hydrocarbon, R 2 is a C 1-4 alkyl, an unsaturated C 2-4 aliphatic hydrocarbon, a phenyl C 1-4 alkyl or a cycloalkyl C 1-4 alkyl; or B is a pyrrolidin-1-yl, piperidino, perhydroazepin-1-yl, morpholino, thiomorpholino, piperazin - 1- yl or 4 - methylpiperazin - 1 - yl, and pharmaceutically acceptable acid addition salts thereof may be prepared by reacting a functional derivative of dihydroapovincaminic acid with an appropriate amine followed optionally by salt formation. Pharmaceutical compositions of compounds of the invention with the usual excipients act as coronary dilators and cellular oxygenaters when administered orally, endorectally, parenterally or topically.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2794074A GB1461300A (en) | 1974-06-24 | 1974-06-24 | Dihydroapovincaminic acid amides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2794074A GB1461300A (en) | 1974-06-24 | 1974-06-24 | Dihydroapovincaminic acid amides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1461300A true GB1461300A (en) | 1977-01-13 |
Family
ID=10267730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2794074A Expired GB1461300A (en) | 1974-06-24 | 1974-06-24 | Dihydroapovincaminic acid amides |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1461300A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992010495A1 (en) * | 1990-12-07 | 1992-06-25 | Richter Gedeon Vegyészeti Gyár Rt. | Novel 14-(n-substituted aminomethyl)eburnane derivatives, process for their preparation and compositions containing them |
-
1974
- 1974-06-24 GB GB2794074A patent/GB1461300A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992010495A1 (en) * | 1990-12-07 | 1992-06-25 | Richter Gedeon Vegyészeti Gyár Rt. | Novel 14-(n-substituted aminomethyl)eburnane derivatives, process for their preparation and compositions containing them |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |