GB1453239A - Vitamin e active product and a method of preparing same - Google Patents
Vitamin e active product and a method of preparing sameInfo
- Publication number
- GB1453239A GB1453239A GB1885874A GB1885874A GB1453239A GB 1453239 A GB1453239 A GB 1453239A GB 1885874 A GB1885874 A GB 1885874A GB 1885874 A GB1885874 A GB 1885874A GB 1453239 A GB1453239 A GB 1453239A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vitamin
- active product
- preparing same
- reaction
- ahrens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 244000144725 Amygdalus communis Species 0.000 abstract 1
- 235000011437 Amygdalus communis Nutrition 0.000 abstract 1
- IELOKBJPULMYRW-NJQVLOCASA-N D-alpha-Tocopheryl Acid Succinate Chemical compound OC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C IELOKBJPULMYRW-NJQVLOCASA-N 0.000 abstract 1
- 239000004264 Petrolatum Substances 0.000 abstract 1
- 229930003427 Vitamin E Natural products 0.000 abstract 1
- 239000008168 almond oil Substances 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000002480 mineral oil Substances 0.000 abstract 1
- 235000010446 mineral oil Nutrition 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 abstract 1
- 229940066842 petrolatum Drugs 0.000 abstract 1
- 235000019271 petrolatum Nutrition 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 229940046009 vitamin E Drugs 0.000 abstract 1
- 235000019165 vitamin E Nutrition 0.000 abstract 1
- 239000011709 vitamin E Substances 0.000 abstract 1
- 150000003712 vitamin E derivatives Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1453239 Vitamin E derivatives G W AHRENS 30 April 1974 18858/74 Heading C2V A vitamin E active product is obtained by heating d-alpha-tocopheryl acid succinate with anhydrous mineral oil, petrolatum or sweet almond oil, at 110‹ to 145‹ C., and removing water formed during the reaction. Magnesium stearate may be included in the reaction. The products may be dissolved in oils and creams for topical application. Examples are given.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1885874A GB1453239A (en) | 1974-04-30 | 1974-04-30 | Vitamin e active product and a method of preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1885874A GB1453239A (en) | 1974-04-30 | 1974-04-30 | Vitamin e active product and a method of preparing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1453239A true GB1453239A (en) | 1976-10-20 |
Family
ID=10119620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1885874A Expired GB1453239A (en) | 1974-04-30 | 1974-04-30 | Vitamin e active product and a method of preparing same |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1453239A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0001851A1 (en) * | 1977-10-29 | 1979-05-16 | Akzo N.V. | Highly concentrated pharmaceutical formulations of steroids and processes for their preparation |
| WO1983001898A1 (en) * | 1981-11-24 | 1983-06-09 | Dennis Rocke | Pharmaceutical preparations and compositions |
| DE3507791A1 (en) * | 1984-03-07 | 1985-09-26 | Roshdy Ismail | Composition for protecting the skin |
| EP0158090A1 (en) * | 1984-03-07 | 1985-10-16 | Roshdy Dr. Ismail | Drug for the treatment and the protection of the skin |
| EP0163924A1 (en) * | 1984-05-02 | 1985-12-11 | Roshdy Dr. Ismail | Vitamin medicine for the treatment and protection of mucous membranes, and use of vitamin E for manufacturing the medicine |
| US5541220A (en) * | 1984-03-07 | 1996-07-30 | Ismail; Roshdy | Agents for the treatment and protection of the skin |
| US11497714B2 (en) | 2020-10-06 | 2022-11-15 | Sadat A. Al Ali | Nano-carrier topical composition with vitamin D3 |
-
1974
- 1974-04-30 GB GB1885874A patent/GB1453239A/en not_active Expired
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0001851A1 (en) * | 1977-10-29 | 1979-05-16 | Akzo N.V. | Highly concentrated pharmaceutical formulations of steroids and processes for their preparation |
| US4212863A (en) | 1977-10-29 | 1980-07-15 | Akzo N.V. | Highly concentrated pharmaceutical formulations of steroids and processes for their preparation |
| WO1983001898A1 (en) * | 1981-11-24 | 1983-06-09 | Dennis Rocke | Pharmaceutical preparations and compositions |
| US4564522A (en) * | 1981-11-24 | 1986-01-14 | Shelleden Products Limited | Pharmaceutical preparations and compositions |
| DE3507791A1 (en) * | 1984-03-07 | 1985-09-26 | Roshdy Ismail | Composition for protecting the skin |
| EP0158090A1 (en) * | 1984-03-07 | 1985-10-16 | Roshdy Dr. Ismail | Drug for the treatment and the protection of the skin |
| US5541220A (en) * | 1984-03-07 | 1996-07-30 | Ismail; Roshdy | Agents for the treatment and protection of the skin |
| US5652261A (en) * | 1984-03-07 | 1997-07-29 | Ismail; Roshdy | Method for the treatment and protection of the skin |
| US5786384A (en) * | 1984-03-07 | 1998-07-28 | Ismail; Roshdy | Agents for the treatment and protection of the skin |
| EP0163924A1 (en) * | 1984-05-02 | 1985-12-11 | Roshdy Dr. Ismail | Vitamin medicine for the treatment and protection of mucous membranes, and use of vitamin E for manufacturing the medicine |
| US11497714B2 (en) | 2020-10-06 | 2022-11-15 | Sadat A. Al Ali | Nano-carrier topical composition with vitamin D3 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |