GB1451180A - Alkylsulphonylphenoxypropanolamines - Google Patents
AlkylsulphonylphenoxypropanolaminesInfo
- Publication number
- GB1451180A GB1451180A GB1265275A GB1265275A GB1451180A GB 1451180 A GB1451180 A GB 1451180A GB 1265275 A GB1265275 A GB 1265275A GB 1265275 A GB1265275 A GB 1265275A GB 1451180 A GB1451180 A GB 1451180A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- image
- group
- alkylsulphonylphenoxypropanolamines
- amine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001412 amines Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002366 halogen compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Alkylsulphonylphenoxypropanolamines of the formula I are prepared <IMAGE> in which the radicals R1 to R4 have the meanings stated in Claim 1, by reacting a corresponding phenol with a compound of the formula <IMAGE> in which X is halogen or a group of the formula <IMAGE> in which R5 is a group which can be eliminated by hydrogenation. Subsequently, either the resulting halogen compound is condensed with an amine of the formula H2N-R1, or the resulting amine is hydrogenated to remove the group R5. The prepared compounds have good cardioselective, beta -adrenergic blocking properties and are therefore suitable for the treatment of cardiopathies.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45509974A | 1974-03-27 | 1974-03-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1451180A true GB1451180A (en) | 1976-09-29 |
Family
ID=23807402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1265275A Expired GB1451180A (en) | 1974-03-27 | 1975-03-26 | Alkylsulphonylphenoxypropanolamines |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5822478B2 (en) |
| BE (1) | BE826873A (en) |
| CA (1) | CA1055528A (en) |
| CH (1) | CH612932A5 (en) |
| DE (1) | DE2513806A1 (en) |
| DK (1) | DK144246C (en) |
| FI (1) | FI62065C (en) |
| FR (2) | FR2265358B1 (en) |
| GB (1) | GB1451180A (en) |
| IE (1) | IE40887B1 (en) |
| LU (1) | LU72100A1 (en) |
| NL (1) | NL7503489A (en) |
| NO (1) | NO140856C (en) |
| SE (1) | SE424548B (en) |
| YU (2) | YU59175A (en) |
| ZA (1) | ZA751853B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6358515B2 (en) | 1997-01-30 | 2002-03-19 | Senju Pharmaceutical Co., Ltd. | Hydroquinone derivatives |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117128A (en) | 1976-08-03 | 1978-09-26 | Smithkline Corporation | Sulfonyl benzofurans and benzothiophenes having coronary vasodilator activity |
| DE4499581D2 (en) * | 1993-12-07 | 1997-09-18 | S & R Maschbau Gmbh | Method and device for baking cakes |
-
1975
- 1975-03-11 CA CA221,803A patent/CA1055528A/en not_active Expired
- 1975-03-12 YU YU00591/75A patent/YU59175A/en unknown
- 1975-03-19 BE BE154495A patent/BE826873A/en unknown
- 1975-03-20 JP JP50033124A patent/JPS5822478B2/en not_active Expired
- 1975-03-20 LU LU72100A patent/LU72100A1/xx unknown
- 1975-03-24 DK DK123875A patent/DK144246C/en active
- 1975-03-24 NL NL7503489A patent/NL7503489A/en not_active Application Discontinuation
- 1975-03-24 FR FR7509047A patent/FR2265358B1/fr not_active Expired
- 1975-03-24 FI FI750875A patent/FI62065C/en not_active IP Right Cessation
- 1975-03-24 ZA ZA00751853A patent/ZA751853B/en unknown
- 1975-03-24 NO NO750993A patent/NO140856C/en unknown
- 1975-03-26 SE SE7503582A patent/SE424548B/en unknown
- 1975-03-26 GB GB1265275A patent/GB1451180A/en not_active Expired
- 1975-03-26 IE IE670/75A patent/IE40887B1/en unknown
- 1975-03-27 CH CH399675A patent/CH612932A5/en not_active IP Right Cessation
- 1975-03-27 DE DE19752513806 patent/DE2513806A1/en not_active Ceased
-
1978
- 1978-08-31 FR FR7825229A patent/FR2391725A1/en active Granted
-
1982
- 1982-06-03 YU YU01171/82A patent/YU117182A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6358515B2 (en) | 1997-01-30 | 2002-03-19 | Senju Pharmaceutical Co., Ltd. | Hydroquinone derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| IE40887B1 (en) | 1979-09-12 |
| AU7839175A (en) | 1976-08-26 |
| IE40887L (en) | 1975-09-27 |
| FI62065B (en) | 1982-07-30 |
| YU59175A (en) | 1982-10-31 |
| SE7503582L (en) | 1975-09-29 |
| LU72100A1 (en) | 1976-02-04 |
| BE826873A (en) | 1975-09-19 |
| FR2265358A1 (en) | 1975-10-24 |
| DK123875A (en) | 1975-09-28 |
| JPS50130736A (en) | 1975-10-16 |
| FI750875A7 (en) | 1975-09-28 |
| CH612932A5 (en) | 1979-08-31 |
| NL7503489A (en) | 1975-09-30 |
| FR2265358B1 (en) | 1980-02-08 |
| DE2513806A1 (en) | 1975-10-09 |
| JPS5822478B2 (en) | 1983-05-09 |
| FR2391725A1 (en) | 1978-12-22 |
| DK144246C (en) | 1982-06-28 |
| NO140856C (en) | 1979-11-28 |
| ZA751853B (en) | 1976-02-25 |
| FR2391725B1 (en) | 1981-07-17 |
| DK144246B (en) | 1982-01-25 |
| YU117182A (en) | 1982-10-31 |
| NO140856B (en) | 1979-08-20 |
| NO750993L (en) | 1975-09-30 |
| SE424548B (en) | 1982-07-26 |
| FI62065C (en) | 1982-11-10 |
| CA1055528A (en) | 1979-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |