GB1326928A - Therapeutic material - Google Patents
Therapeutic materialInfo
- Publication number
- GB1326928A GB1326928A GB6124070A GB6124070A GB1326928A GB 1326928 A GB1326928 A GB 1326928A GB 6124070 A GB6124070 A GB 6124070A GB 6124070 A GB6124070 A GB 6124070A GB 1326928 A GB1326928 A GB 1326928A
- Authority
- GB
- United Kingdom
- Prior art keywords
- therapeutic material
- precipitation
- liquid
- subjecting
- dec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000463 material Substances 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title abstract 4
- 238000001556 precipitation Methods 0.000 abstract 4
- 239000007788 liquid Substances 0.000 abstract 3
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 239000006285 cell suspension Substances 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- 239000002244 precipitate Substances 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 210000003563 lymphoid tissue Anatomy 0.000 abstract 1
- CGFYHILWFSGVJS-UHFFFAOYSA-N silicic acid;trioxotungsten Chemical compound O[Si](O)(O)O.O=[W]1(=O)O[W](=O)(=O)O[W](=O)(=O)O1.O=[W]1(=O)O[W](=O)(=O)O[W](=O)(=O)O1.O=[W]1(=O)O[W](=O)(=O)O[W](=O)(=O)O1.O=[W]1(=O)O[W](=O)(=O)O[W](=O)(=O)O1 CGFYHILWFSGVJS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1326928 Therapeutic material INSTITUT PASTEUR 23 Dec 1970 [31 Dec 1969] 61240/ 70 Heading A5B A therapeutic material, capable of inhibiting the development of leukaemia and other cancers, is prepared by subjecting a cell suspension to a first precipitation with polyethyleneglycol; separating the precipitate from the liquid; subjecting the liquid to a second precipitation with silico-tungstic acid, e.g. silicoduodecitungstic acid; and separating the therapeutic material containing liquid from the precipitate. The cell suspension may comprise (i) cells of normal lymphoid tissues, (2) cultures in vitro of cells which are derived from (1), or (3) cell cultures infected with a virus of the leukaemic type. Both precipitations may be carried out at a temperature from -10 to +10‹C. From 2 to 10% by weight of polyethylene glycol may be added in the first precipitation.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6945776A FR2073293B1 (en) | 1969-12-31 | 1969-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1326928A true GB1326928A (en) | 1973-08-15 |
Family
ID=9045518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6124070A Expired GB1326928A (en) | 1969-12-31 | 1970-12-23 | Therapeutic material |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS4940922B1 (en) |
| AT (1) | AT301749B (en) |
| BE (1) | BE760727A (en) |
| CA (1) | CA956573A (en) |
| CH (1) | CH533988A (en) |
| DE (1) | DE2064296C2 (en) |
| DK (1) | DK128054B (en) |
| FR (1) | FR2073293B1 (en) |
| GB (1) | GB1326928A (en) |
| LU (1) | LU62332A1 (en) |
| NL (1) | NL7019097A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0027429A3 (en) * | 1979-10-11 | 1982-05-12 | Liborio Dr. Bonifacio | Tumor antidote (oncoclasine) for the cure of tumors, and process for its extraction |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK144731C (en) | 1976-07-30 | 1982-10-18 | Nordisk Insulinlab | PROCEDURE FOR INSULATING PROTEIN HORMONES DERIVED FROM HUMAN HYPPHYPHYSE TISSUE |
| JPS5330639U (en) * | 1976-08-20 | 1978-03-16 | ||
| JPS5925332A (en) * | 1982-08-04 | 1984-02-09 | Mochida Pharmaceut Co Ltd | Preparation of antitumor glycoprotein |
| FR2568125B1 (en) * | 1984-07-25 | 1988-04-15 | Kogo Michiko | ANTI-TUMOR AGENT CONTAINING SUGAR PROTEIN |
| GB8614733D0 (en) * | 1986-06-17 | 1986-07-23 | Lefesvre A | Aids treatment |
-
1969
- 1969-12-31 FR FR6945776A patent/FR2073293B1/fr not_active Expired
-
1970
- 1970-12-22 CA CA101,323A patent/CA956573A/en not_active Expired
- 1970-12-23 BE BE760727A patent/BE760727A/en not_active IP Right Cessation
- 1970-12-23 CH CH1913270A patent/CH533988A/en not_active IP Right Cessation
- 1970-12-23 GB GB6124070A patent/GB1326928A/en not_active Expired
- 1970-12-28 LU LU62332D patent/LU62332A1/xx unknown
- 1970-12-29 AT AT1170570A patent/AT301749B/en not_active IP Right Cessation
- 1970-12-29 DE DE19702064296 patent/DE2064296C2/en not_active Expired
- 1970-12-30 JP JP45125049A patent/JPS4940922B1/ja active Pending
- 1970-12-31 NL NL7019097A patent/NL7019097A/xx unknown
-
1971
- 1971-01-04 DK DK271A patent/DK128054B/en not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0027429A3 (en) * | 1979-10-11 | 1982-05-12 | Liborio Dr. Bonifacio | Tumor antidote (oncoclasine) for the cure of tumors, and process for its extraction |
| US4462987A (en) * | 1979-10-11 | 1984-07-31 | Liborio Bonifacio | Process and composition for treating tumors in mice |
Also Published As
| Publication number | Publication date |
|---|---|
| BE760727A (en) | 1971-05-27 |
| DE2064296A1 (en) | 1971-07-15 |
| CH533988A (en) | 1973-02-28 |
| NL7019097A (en) | 1971-07-02 |
| FR2073293A1 (en) | 1971-10-01 |
| FR2073293B1 (en) | 1973-01-12 |
| AT301749B (en) | 1972-09-11 |
| LU62332A1 (en) | 1971-05-27 |
| DK128054B (en) | 1974-02-25 |
| CA956573A (en) | 1974-10-22 |
| JPS4940922B1 (en) | 1974-11-06 |
| DE2064296C2 (en) | 1984-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |