GB1318815A - Specific chemical probes - Google Patents
Specific chemical probesInfo
- Publication number
- GB1318815A GB1318815A GB1756671A GB1756671A GB1318815A GB 1318815 A GB1318815 A GB 1318815A GB 1756671 A GB1756671 A GB 1756671A GB 1756671 A GB1756671 A GB 1756671A GB 1318815 A GB1318815 A GB 1318815A
- Authority
- GB
- United Kingdom
- Prior art keywords
- incorporating
- coated
- test reagent
- electrodes
- thin film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000523 sample Substances 0.000 title abstract 3
- 239000000126 substance Substances 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- 238000000840 electrochemical analysis Methods 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- 239000010409 thin film Substances 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 229920002301 cellulose acetate Polymers 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052737 gold Inorganic materials 0.000 abstract 1
- 239000010931 gold Substances 0.000 abstract 1
- 238000009413 insulation Methods 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000004332 silver Substances 0.000 abstract 1
- 238000004832 voltammetry Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1495—Calibrating or testing of in-vivo probes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
1318815 Electrochemical analysis MILES LABORATORIES Inc 27 May 1971 [8 June 1970] 17566/71 Heading G1N An electrochemical analysis probe includes an insulating base member 10 carrying a pair of spaced thin film electrode elements 11, 22 coated with a semi-permeable matrix 12 incorporating a test reagent. The electrodes 11, 22 of silver, gold or platinum or carbon are deposited and formed by thin film printed circuit techniques, coated by insulation 13 in the middle region and at their end by a cellulose acetate semipermeable membrane gel 12 incorporating an immobilized urea-determining test reagent e. g. arease. Exposed terminals 23, 23a plug into handle 21. The electrode system 11, 22 may be duplicated on the opposite side of base 10 and coated with a membrane layer not incorporating a test reagent. An oscillator is connected to the two sets of electrodes, Fig.3 (not shown) and the outputs proportional to the conductivity compared in a summing amplifier, the output of which is applied to an indicator or differentiated to give the direction of change of the differential conductivity. The system of Fig.3 (not shown) may be used for detecting glucose, urea enzymes in blood. the probe may be used for in voltammetry and E M F measurements.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4436470A | 1970-06-08 | 1970-06-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1318815A true GB1318815A (en) | 1973-05-31 |
Family
ID=21931978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1756671A Expired GB1318815A (en) | 1970-06-08 | 1971-05-27 | Specific chemical probes |
Country Status (8)
| Country | Link |
|---|---|
| AU (1) | AU2959071A (en) |
| BE (1) | BE768183A (en) |
| CH (1) | CH524142A (en) |
| DE (1) | DE2127142A1 (en) |
| FR (1) | FR2096026A5 (en) |
| GB (1) | GB1318815A (en) |
| NL (1) | NL7107831A (en) |
| ZA (1) | ZA713322B (en) |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0121385A1 (en) * | 1983-03-26 | 1984-10-10 | Cambridge Life Sciences Plc | Conductimetric bioassay techniques |
| EP0136362A4 (en) * | 1983-03-11 | 1988-01-07 | Matsushita Electric Industrial Co Ltd | BIOCAPTOR. |
| GB2204408A (en) * | 1987-03-04 | 1988-11-09 | Plessey Co Plc | Biosensor device |
| WO1988009808A3 (en) * | 1987-06-05 | 1989-04-06 | Little Inc A | Receptor-based biosensors |
| GB2217461A (en) * | 1988-03-10 | 1989-10-25 | Atomic Energy Authority Uk | Making microelectrode assembly |
| WO1990001700A1 (en) * | 1988-08-03 | 1990-02-22 | Battelle Memorial Institute | Methods and devices for carrying out multiple simultaneous conductometric analyses |
| US5192507A (en) * | 1987-06-05 | 1993-03-09 | Arthur D. Little, Inc. | Receptor-based biosensors |
| WO1994016095A1 (en) * | 1993-01-13 | 1994-07-21 | Avocet Medical, Inc. | Method, test article, and system for performing assays |
| US5509410A (en) * | 1983-06-06 | 1996-04-23 | Medisense, Inc. | Strip electrode including screen printing of a single layer |
| US5628890A (en) * | 1995-09-27 | 1997-05-13 | Medisense, Inc. | Electrochemical sensor |
| US5682884A (en) * | 1983-05-05 | 1997-11-04 | Medisense, Inc. | Strip electrode with screen printing |
| US6997343B2 (en) | 2001-11-14 | 2006-02-14 | Hypoguard Limited | Sensor dispensing device |
| US7045054B1 (en) | 1999-09-20 | 2006-05-16 | Roche Diagnostics Corporation | Small volume biosensor for continuous analyte monitoring |
| US7250095B2 (en) | 2002-07-11 | 2007-07-31 | Hypoguard Limited | Enzyme electrodes and method of manufacture |
| US7264139B2 (en) | 2003-01-14 | 2007-09-04 | Hypoguard Limited | Sensor dispensing device |
| US7550069B2 (en) | 1998-10-08 | 2009-06-23 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US7906009B2 (en) | 1997-02-06 | 2011-03-15 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US9689821B2 (en) | 2008-12-31 | 2017-06-27 | Spd Swiss Precision Diagnostics Gmbh | Conductivity measurement cell |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE407115B (en) * | 1975-10-06 | 1979-03-12 | Kabi Ab | PROCEDURES AND METAL ELECTRODES FOR THE STUDY OF ENZYMATIC AND OTHER BIOCHEMICAL REACTIONS |
| DE3279210D1 (en) * | 1982-06-14 | 1988-12-15 | Ohmicron Corp | Semiconductor device, sensor and method for determining the concentration of an analyte in a medium |
| CA1226036A (en) * | 1983-05-05 | 1987-08-25 | Irving J. Higgins | Analytical equipment and sensor electrodes therefor |
| GB9107193D0 (en) * | 1991-04-05 | 1991-05-22 | Wilson Robert | Analytical devices |
| DE4123348A1 (en) * | 1991-07-15 | 1993-01-21 | Boehringer Mannheim Gmbh | ELECTROCHEMICAL ANALYSIS SYSTEM |
| FR2701117B1 (en) * | 1993-02-04 | 1995-03-10 | Asulab Sa | Electrochemical measurement system with multizone sensor, and its application to glucose measurement. |
| FR2705150B1 (en) * | 1993-05-10 | 1995-07-21 | Asulab Sa | Multiple zone electrochemical sensor on disk and its application to glucose measurement. |
| WO2001049484A1 (en) | 2000-01-05 | 2001-07-12 | Saint-Gobain Technical Fabrics Of America, Inc. | Smooth reinforced cementitious boards and methods of making same |
| US7049251B2 (en) | 2003-01-21 | 2006-05-23 | Saint-Gobain Technical Fabrics Canada Ltd | Facing material with controlled porosity for construction boards |
| TWI383550B (en) * | 2009-12-07 | 2013-01-21 | Univ Nat Taiwan Science Tech | Converter and electrochemical detecting device utilizing the same |
-
1971
- 1971-04-29 CH CH634671A patent/CH524142A/en not_active IP Right Cessation
- 1971-05-24 ZA ZA713322A patent/ZA713322B/en unknown
- 1971-05-27 GB GB1756671A patent/GB1318815A/en not_active Expired
- 1971-06-01 DE DE19712127142 patent/DE2127142A1/en active Pending
- 1971-06-02 AU AU29590/71A patent/AU2959071A/en not_active Expired
- 1971-06-07 BE BE768183A patent/BE768183A/en unknown
- 1971-06-07 FR FR7120591A patent/FR2096026A5/fr not_active Expired
- 1971-06-08 NL NL7107831A patent/NL7107831A/xx unknown
Cited By (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0136362A4 (en) * | 1983-03-11 | 1988-01-07 | Matsushita Electric Industrial Co Ltd | BIOCAPTOR. |
| WO1984003945A1 (en) * | 1983-03-26 | 1984-10-11 | Cambridge Life Sciences | Conductimetric bioassay techniques |
| EP0121385A1 (en) * | 1983-03-26 | 1984-10-10 | Cambridge Life Sciences Plc | Conductimetric bioassay techniques |
| US5820551A (en) * | 1983-05-05 | 1998-10-13 | Hill; Hugh Allen Oliver | Strip electrode with screen printing |
| US5727548A (en) * | 1983-05-05 | 1998-03-17 | Medisense, Inc. | Strip electrode with screen printing |
| US5682884A (en) * | 1983-05-05 | 1997-11-04 | Medisense, Inc. | Strip electrode with screen printing |
| US5509410A (en) * | 1983-06-06 | 1996-04-23 | Medisense, Inc. | Strip electrode including screen printing of a single layer |
| GB2204408A (en) * | 1987-03-04 | 1988-11-09 | Plessey Co Plc | Biosensor device |
| US5001048A (en) * | 1987-06-05 | 1991-03-19 | Aurthur D. Little, Inc. | Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film |
| WO1988009808A3 (en) * | 1987-06-05 | 1989-04-06 | Little Inc A | Receptor-based biosensors |
| US5192507A (en) * | 1987-06-05 | 1993-03-09 | Arthur D. Little, Inc. | Receptor-based biosensors |
| GB2217461A (en) * | 1988-03-10 | 1989-10-25 | Atomic Energy Authority Uk | Making microelectrode assembly |
| WO1990001700A1 (en) * | 1988-08-03 | 1990-02-22 | Battelle Memorial Institute | Methods and devices for carrying out multiple simultaneous conductometric analyses |
| US5344754A (en) * | 1993-01-13 | 1994-09-06 | Avocet Medical, Inc. | Assay timed by electrical resistance change and test strip |
| US5554531A (en) * | 1993-01-13 | 1996-09-10 | Avocet Medical, Inc. | Device for performing timed assay by electrical resistance change |
| WO1994016095A1 (en) * | 1993-01-13 | 1994-07-21 | Avocet Medical, Inc. | Method, test article, and system for performing assays |
| US5628890A (en) * | 1995-09-27 | 1997-05-13 | Medisense, Inc. | Electrochemical sensor |
| US8105476B2 (en) | 1997-02-06 | 2012-01-31 | Abbott Diabetes Care Inc. | Integrated lancing and measurement device |
| US8808531B2 (en) | 1997-02-06 | 2014-08-19 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US9234864B2 (en) | 1997-02-06 | 2016-01-12 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8142643B2 (en) | 1997-02-06 | 2012-03-27 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8142642B2 (en) | 1997-02-06 | 2012-03-27 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8123929B2 (en) | 1997-02-06 | 2012-02-28 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8118992B2 (en) | 1997-02-06 | 2012-02-21 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US7906009B2 (en) | 1997-02-06 | 2011-03-15 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US7909984B2 (en) | 1997-02-06 | 2011-03-22 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US7988845B2 (en) | 1997-02-06 | 2011-08-02 | Abbott Diabetes Care Inc. | Integrated lancing and measurement device and analyte measuring methods |
| US8114270B2 (en) | 1997-02-06 | 2012-02-14 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8114271B2 (en) | 1997-02-06 | 2012-02-14 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8268163B2 (en) | 1998-10-08 | 2012-09-18 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8262996B2 (en) | 1998-10-08 | 2012-09-11 | Abbott Diabetes Care Inc. | Small volume in vitro sensor and methods of making |
| US8091220B2 (en) | 1998-10-08 | 2012-01-10 | Abbott Diabetes Care Inc. | Methods of making small volume in vitro analyte sensors |
| US8083924B2 (en) | 1998-10-08 | 2011-12-27 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8083929B2 (en) | 1998-10-08 | 2011-12-27 | Abbott Diabetes Care Inc. | Small volume in vitro sensor and methods of making |
| US8083928B2 (en) | 1998-10-08 | 2011-12-27 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8118993B2 (en) | 1998-10-08 | 2012-02-21 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US9891185B2 (en) | 1998-10-08 | 2018-02-13 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US7563350B2 (en) | 1998-10-08 | 2009-07-21 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US7550069B2 (en) | 1998-10-08 | 2009-06-23 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US9341591B2 (en) | 1998-10-08 | 2016-05-17 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8153063B2 (en) | 1998-10-08 | 2012-04-10 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8163164B2 (en) | 1998-10-08 | 2012-04-24 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8182671B2 (en) | 1998-10-08 | 2012-05-22 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8182670B2 (en) | 1998-10-08 | 2012-05-22 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8187895B2 (en) | 1998-10-08 | 2012-05-29 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8186044B2 (en) | 1998-10-08 | 2012-05-29 | Abbott Diabetes Care Inc. | Method of manufacturing small volume in vitro analyte sensors |
| US8192611B2 (en) | 1998-10-08 | 2012-06-05 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8211363B2 (en) | 1998-10-08 | 2012-07-03 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8221685B2 (en) | 1998-10-08 | 2012-07-17 | Abbott Diabetes Care Inc. | Small volume in vitro sensor and methods of making |
| US8226815B2 (en) | 1998-10-08 | 2012-07-24 | Abbott Diabetes Care Inc. | Small volume in vitro sensor and methods of making |
| US8087162B2 (en) | 1998-10-08 | 2012-01-03 | Abbott Diabetes Care Inc. | Methods of making small volume in vitro analyte sensors |
| US9316609B2 (en) | 1998-10-08 | 2016-04-19 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US8268144B2 (en) | 1998-10-08 | 2012-09-18 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8273241B2 (en) | 1998-10-08 | 2012-09-25 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8272125B2 (en) | 1998-10-08 | 2012-09-25 | Abbott Diabetes Care Inc. | Method of manufacturing in vitro analyte sensors |
| US8372261B2 (en) | 1998-10-08 | 2013-02-12 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8377378B2 (en) | 1998-10-08 | 2013-02-19 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8425758B2 (en) | 1998-10-08 | 2013-04-23 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8425743B2 (en) | 1998-10-08 | 2013-04-23 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8449758B2 (en) | 1998-10-08 | 2013-05-28 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor and methods of making |
| US8650751B2 (en) | 1998-10-08 | 2014-02-18 | Abbott Diabetes Care Inc. | Methods of making small volume in vitro analyte sensors |
| US8701282B2 (en) | 1998-10-08 | 2014-04-22 | Abbott Diabetes Care Inc. | Method for manufacturing a biosensor |
| US8728297B2 (en) | 1998-10-08 | 2014-05-20 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US9291592B2 (en) | 1998-10-08 | 2016-03-22 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US9234863B2 (en) | 1998-10-08 | 2016-01-12 | Abbott Diabetes Care Inc. | Small volume in vitro analyte sensor |
| US7045054B1 (en) | 1999-09-20 | 2006-05-16 | Roche Diagnostics Corporation | Small volume biosensor for continuous analyte monitoring |
| US7731835B2 (en) | 1999-09-20 | 2010-06-08 | Roche Diagnostics Operations, Inc. | Electrochemical sensor and method for continuous analyte monitoring |
| US6997343B2 (en) | 2001-11-14 | 2006-02-14 | Hypoguard Limited | Sensor dispensing device |
| US7250095B2 (en) | 2002-07-11 | 2007-07-31 | Hypoguard Limited | Enzyme electrodes and method of manufacture |
| US7264139B2 (en) | 2003-01-14 | 2007-09-04 | Hypoguard Limited | Sensor dispensing device |
| US9689821B2 (en) | 2008-12-31 | 2017-06-27 | Spd Swiss Precision Diagnostics Gmbh | Conductivity measurement cell |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2959071A (en) | 1972-12-07 |
| ZA713322B (en) | 1972-01-26 |
| FR2096026A5 (en) | 1972-02-11 |
| NL7107831A (en) | 1971-12-10 |
| DE2127142A1 (en) | 1971-12-16 |
| CH524142A (en) | 1972-06-15 |
| BE768183A (en) | 1971-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |