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GB1318720A - Apparatus for identifying particles according to their microstructure variations - Google Patents

Apparatus for identifying particles according to their microstructure variations

Info

Publication number
GB1318720A
GB1318720A GB5412770A GB5412770A GB1318720A GB 1318720 A GB1318720 A GB 1318720A GB 5412770 A GB5412770 A GB 5412770A GB 5412770 A GB5412770 A GB 5412770A GB 1318720 A GB1318720 A GB 1318720A
Authority
GB
United Kingdom
Prior art keywords
nov
leads
diffraction grating
light beam
passes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5412770A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Calspan Corp
Original Assignee
Calspan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calspan Corp filed Critical Calspan Corp
Publication of GB1318720A publication Critical patent/GB1318720A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1454—Optical arrangements using phase shift or interference, e.g. for improving contrast

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

1318720 Counting particles CORNELL AERONAUTICAL LABORATORY Inc 13 Nov 1970 [18 Nov 1969] 54127/70 Heading G4D [Also in Division G1] Liquid-borne particles are detected by passing them through a light beam which then passes through a diffraction grating 44. A sample of blood and diluent is driven by an impeller 12 through a flattened micro-capillary tube 33 past a light beam. The beam passes through a diffraction grating 44 to cast an image on a plane 46, a small part of which includes a photodetector 48. The output 49 is compared with that 51 of a background detector and sent to a signal analyzer 52. Depending on the characteristics, Fig. 5, of five types of white cell, red cells, and platelets, so signals appear on one or more of three leads 56, 58, 60, to mark one of leads 64-76 to register on an appropriate counter. At the same time a sorter 78 is operated (Fig. 7, not shown) to collect the detected particle.
GB5412770A 1969-11-18 1970-11-13 Apparatus for identifying particles according to their microstructure variations Expired GB1318720A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87772969A 1969-11-18 1969-11-18

Publications (1)

Publication Number Publication Date
GB1318720A true GB1318720A (en) 1973-05-31

Family

ID=25370595

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5412770A Expired GB1318720A (en) 1969-11-18 1970-11-13 Apparatus for identifying particles according to their microstructure variations

Country Status (10)

Country Link
BE (1) BE758948A (en)
CA (1) CA932551A (en)
CH (1) CH534354A (en)
DE (1) DE2056291A1 (en)
ES (1) ES385591A1 (en)
FR (1) FR2069514A5 (en)
GB (1) GB1318720A (en)
LU (1) LU62070A1 (en)
NL (1) NL7016704A (en)
SE (1) SE372416B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000011449A1 (en) * 1998-08-21 2000-03-02 Union Biometrica, Inc. Instrument for selecting and depositing multicellular organisms and other large objects
EP1739402B1 (en) * 2004-04-23 2017-08-02 The Furukawa Electric Co., Ltd. Methods of separating, identifying and dispensing specimen and device therefor, and analyzing device method

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2535053B1 (en) * 1982-10-22 1985-06-21 Saint Etienne Universite APPARATUS FOR OPTICAL IDENTIFICATION OF INDIVIDUAL MULTIPARAMETRIC PROPERTIES OF PARTICLES OR OBJECTS IN CONTINUOUS FLOW
US4606636A (en) * 1983-10-25 1986-08-19 Universite De Saint-Etienne Optical apparatus for identifying the individual multiparametric properties of particles or bodies in a continuous flow
US5733507A (en) * 1995-06-07 1998-03-31 Inphocyte, Inc. Biological cell sample holder for use in infrared and/or Raman spectroscopy analysis holder
US5848977A (en) * 1996-02-16 1998-12-15 Inphocyte, Inc. Sample holder for cells
CN112752964A (en) * 2018-10-01 2021-05-04 惠普发展公司，有限责任合伙企业 Bulk particle sorting

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000011449A1 (en) * 1998-08-21 2000-03-02 Union Biometrica, Inc. Instrument for selecting and depositing multicellular organisms and other large objects
US6657713B2 (en) 1998-08-21 2003-12-02 Union Biometrica, Inc. Instrument for selecting and depositing multicellular organisms and other large objects
EP1739402B1 (en) * 2004-04-23 2017-08-02 The Furukawa Electric Co., Ltd. Methods of separating, identifying and dispensing specimen and device therefor, and analyzing device method

Also Published As

Publication number Publication date
LU62070A1 (en) 1971-08-12
CH534354A (en) 1973-02-28
NL7016704A (en) 1971-05-21
DE2056291A1 (en) 1971-05-27
ES385591A1 (en) 1973-03-16
CA932551A (en) 1973-08-28
SE372416B (en) 1974-12-23
FR2069514A5 (en) 1971-09-03
BE758948A (en) 1971-05-13

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees