GB1386965A - 4-nitro pyridine -1- oxide derivatives nad compositions containing the same - Google Patents
4-nitro pyridine -1- oxide derivatives nad compositions containing the sameInfo
- Publication number
- GB1386965A GB1386965A GB808471A GB808471A GB1386965A GB 1386965 A GB1386965 A GB 1386965A GB 808471 A GB808471 A GB 808471A GB 808471 A GB808471 A GB 808471A GB 1386965 A GB1386965 A GB 1386965A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- hydrogen
- same
- compositions containing
- oxide derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RXKNNAKAVAHBNK-UHFFFAOYSA-N 4-nitropyridine-n-oxide Chemical class [O-][N+](=O)C1=CC=[N+]([O-])C=C1 RXKNNAKAVAHBNK-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- -1 C 1-6 alkylene radical Chemical group 0.000 abstract 1
- MZVQCMJNVPIDEA-UHFFFAOYSA-N [CH2]CN(CC)CC Chemical group [CH2]CN(CC)CC MZVQCMJNVPIDEA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1386965 4-Nitro-1-oxide pryidine-2- carboxamides J M D ARON-SAMUEL 29 March 1972 [29 March 1971] 8084/71 Heading C2C Novel compounds (I) and their acid addition salts in which R is hydrogen or C 1-6 alkyl, R 1 is hydrogen or C 1-6 alkyl, R 2 is (a) -(CH 2 ) n -R 3 , where n is 0 to 6 and R 3 is a 3-7 membered heterocycle optionally substituted by C 1-6 alkyl, or (b) -B-N(R 4 )R 5 where B is a C 1-6 alkylene radical, R 4 is hydrogen or C 1-6 alkyl and R 5 is C 1-6 alkyl or NR 1 R 2 form a 3-7 membered heterocycle optionally substituted by C 1-6 alkyl with the proviso that when R and R 1 are hydrogen, R 2 is not diethylaminoethyl, are prepared by reacting a compound of Formula II in which R 6 is alkyl, with an amine of Compounds of Formula I are hypotensive agents and form with a carrier a pharmaceutical composition which may be administered orally parenterally or rectally.
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB808471A GB1386965A (en) | 1971-03-29 | 1971-03-29 | 4-nitro pyridine -1- oxide derivatives nad compositions containing the same |
| FR7207979A FR2132000B1 (en) | 1971-03-29 | 1972-03-08 | |
| BE780552A BE780552A (en) | 1971-03-29 | 1972-03-10 | NEW PYRIDINE COMPOUNDS, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS |
| ZA721728A ZA721728B (en) | 1971-03-29 | 1972-03-14 | New pyridine derivatives,process for their preparation and applications thereof |
| IL38977A IL38977A (en) | 1971-03-29 | 1972-03-14 | Pyridine derivatives,their preparation and pharmaceutical compositions containing them |
| DE19722213843 DE2213843A1 (en) | 1971-03-29 | 1972-03-22 | New pyran compounds, processes for their preparation and their possible applications |
| JP3039372A JPS5317595B1 (en) | 1971-03-29 | 1972-03-28 | |
| AU40501/72A AU467216B2 (en) | 1971-03-29 | 1972-03-28 | New pyridine derivatives, process for their preparation and application thereof |
| NL7204199A NL7204199A (en) | 1971-03-29 | 1972-03-28 | |
| US05/474,316 US3935313A (en) | 1971-03-29 | 1974-05-29 | Pharmaceutical composition containing N-(3-diethyl-aminopropyl)-4-nitro-1-oxide-pyridine-2-carboxamide and process for the treatment of hypertension therewith |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB808471A GB1386965A (en) | 1971-03-29 | 1971-03-29 | 4-nitro pyridine -1- oxide derivatives nad compositions containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1386965A true GB1386965A (en) | 1975-03-12 |
Family
ID=9845448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB808471A Expired GB1386965A (en) | 1971-03-29 | 1971-03-29 | 4-nitro pyridine -1- oxide derivatives nad compositions containing the same |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5317595B1 (en) |
| AU (1) | AU467216B2 (en) |
| BE (1) | BE780552A (en) |
| DE (1) | DE2213843A1 (en) |
| FR (1) | FR2132000B1 (en) |
| GB (1) | GB1386965A (en) |
| IL (1) | IL38977A (en) |
| NL (1) | NL7204199A (en) |
| ZA (1) | ZA721728B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1449841A1 (en) * | 2003-02-19 | 2004-08-25 | Bayer CropScience SA | New fungicidal compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3519717A (en) * | 1968-01-17 | 1970-07-07 | Schering Corp | Novel method for lowering high blood pressure and compositions therefor |
-
1971
- 1971-03-29 GB GB808471A patent/GB1386965A/en not_active Expired
-
1972
- 1972-03-08 FR FR7207979A patent/FR2132000B1/fr not_active Expired
- 1972-03-10 BE BE780552A patent/BE780552A/en unknown
- 1972-03-14 IL IL38977A patent/IL38977A/en unknown
- 1972-03-14 ZA ZA721728A patent/ZA721728B/en unknown
- 1972-03-22 DE DE19722213843 patent/DE2213843A1/en active Pending
- 1972-03-28 JP JP3039372A patent/JPS5317595B1/ja active Pending
- 1972-03-28 AU AU40501/72A patent/AU467216B2/en not_active Expired
- 1972-03-28 NL NL7204199A patent/NL7204199A/xx unknown
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1449841A1 (en) * | 2003-02-19 | 2004-08-25 | Bayer CropScience SA | New fungicidal compounds |
| WO2004074280A1 (en) * | 2003-02-19 | 2004-09-02 | Bayer Cropscience Sa | Pyridine derivatives as fungicidal compounds |
| CN100402525C (en) * | 2003-02-19 | 2008-07-16 | 拜尔农科股份有限公司 | Pyridine derivatives as fungicidal compounds |
| US7754741B2 (en) | 2003-02-19 | 2010-07-13 | Bayer Cropscience S.A. | Pyridine derivatives as fungicidal compounds |
| KR101084022B1 (en) | 2003-02-19 | 2011-11-16 | 바이엘 에스에이에스 | Pyridine Derivatives As Fungicidal Compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5317595B1 (en) | 1978-06-09 |
| FR2132000B1 (en) | 1975-12-26 |
| IL38977A (en) | 1975-02-10 |
| DE2213843A1 (en) | 1972-10-12 |
| AU467216B2 (en) | 1973-10-04 |
| NL7204199A (en) | 1972-10-03 |
| AU4050172A (en) | 1973-10-04 |
| ZA721728B (en) | 1972-12-27 |
| BE780552A (en) | 1972-09-11 |
| FR2132000A1 (en) | 1972-11-17 |
| IL38977A0 (en) | 1972-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |