GB1386210A - 2-methyl-5 nitro-1- 2-heteroaryloxy-ethyl imidazoles - Google Patents
2-methyl-5 nitro-1- 2-heteroaryloxy-ethyl imidazolesInfo
- Publication number
- GB1386210A GB1386210A GB4256273A GB4256273A GB1386210A GB 1386210 A GB1386210 A GB 1386210A GB 4256273 A GB4256273 A GB 4256273A GB 4256273 A GB4256273 A GB 4256273A GB 1386210 A GB1386210 A GB 1386210A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- methyl
- heteroaryloxy
- nitro
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 benzo-(b)- pyridyl Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000005493 quinolyl group Chemical group 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1386210 2 - Methyl - 5 - nitro -1 - [2 - heteroaryloxy)ethyl]-imidazoles G D SEARLE & CO 11 Sept 1973 [11 Sept 1972] 42562/73 Heading C2C Novel compounds of Formula I: wherein R is a pyridyl or quinolyl (benzo-(b)- pyridyl) radical, optionally substituted by 1 to 3 halogen atoms, NO 2 groups and/or methyl groups are obtained by reacting a compound of Formula II: wherein A is a hydrogen atom or a radical of formula -CH 2 CH 2 X (wherein X is halogen, toluenesulphonyloxy or methanesulphonyloxy) with a compound of formula, B-R, wherein B is an alkali metal oxy group when A is -CH 2 CH 2 X or B is a radical of formula -O-CH 2 CH 2 X when A is a hydrogen atom. The imidazole derivatives of Formula I possess anti-microbial activity.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00288111A US3828056A (en) | 1972-09-11 | 1972-09-11 | (2-(2-methyl-5-nitro-1-imidazolyl)ethyl)heteroaryloxy ethers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1386210A true GB1386210A (en) | 1975-03-05 |
Family
ID=23105783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4256273A Expired GB1386210A (en) | 1972-09-11 | 1973-09-11 | 2-methyl-5 nitro-1- 2-heteroaryloxy-ethyl imidazoles |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3828056A (en) |
| JP (1) | JPS4962480A (en) |
| AR (1) | AR197526A1 (en) |
| BE (1) | BE804666A (en) |
| CA (1) | CA1006873A (en) |
| CH (1) | CH582694A5 (en) |
| DE (1) | DE2345521A1 (en) |
| DK (1) | DK135166B (en) |
| ES (1) | ES418666A1 (en) |
| FR (1) | FR2208657B1 (en) |
| GB (1) | GB1386210A (en) |
| NL (1) | NL7312458A (en) |
| ZA (1) | ZA737188B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2522176A1 (en) * | 1975-05-17 | 1976-11-25 | Hoechst Ag | 1-METHYL-2- (PYRIDYL-OXYMETHYL) -NITRO- IMIDAZOLE AND THE METHOD OF MANUFACTURING IT |
| EP1098881A1 (en) * | 1998-07-21 | 2001-05-16 | Syngenta Participations AG | 3-substituted pyridine compounds and related synthesis |
| US6509471B2 (en) | 1998-07-21 | 2003-01-21 | Syngenta Participations Ag | 3-substituted pyridine compounds and related synthesis |
| MY192778A (en) * | 2017-01-06 | 2022-09-08 | Rivus Pharmaceuticals Inc | Novel phenyl derivatives |
| MX2021003724A (en) * | 2018-09-29 | 2021-05-14 | Jiangsu Yahong Meditech Co Ltd | Nitroxoline prodrug and use thereof. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1479120A (en) * | 1965-05-10 | 1967-04-28 | Ward Blenkinsop & Co Ltd | Imidazole compounds and their preparation |
-
1972
- 1972-09-11 US US00288111A patent/US3828056A/en not_active Expired - Lifetime
-
1973
- 1973-09-10 DK DK496673AA patent/DK135166B/en unknown
- 1973-09-10 CA CA180,630A patent/CA1006873A/en not_active Expired
- 1973-09-10 NL NL7312458A patent/NL7312458A/xx not_active Application Discontinuation
- 1973-09-10 DE DE19732345521 patent/DE2345521A1/en active Pending
- 1973-09-10 ZA ZA737188A patent/ZA737188B/en unknown
- 1973-09-10 BE BE135496A patent/BE804666A/en unknown
- 1973-09-11 AR AR250031A patent/AR197526A1/en active
- 1973-09-11 FR FR7332655A patent/FR2208657B1/fr not_active Expired
- 1973-09-11 JP JP48102571A patent/JPS4962480A/ja active Pending
- 1973-09-11 ES ES418666A patent/ES418666A1/en not_active Expired
- 1973-09-11 CH CH1299173A patent/CH582694A5/xx not_active IP Right Cessation
- 1973-09-11 GB GB4256273A patent/GB1386210A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA737188B (en) | 1974-10-30 |
| DK135166C (en) | 1977-09-12 |
| CH582694A5 (en) | 1976-12-15 |
| DE2345521A1 (en) | 1974-03-28 |
| AR197526A1 (en) | 1974-04-15 |
| AU6014273A (en) | 1975-03-13 |
| DK135166B (en) | 1977-03-14 |
| CA1006873A (en) | 1977-03-15 |
| BE804666A (en) | 1974-03-11 |
| FR2208657A1 (en) | 1974-06-28 |
| NL7312458A (en) | 1974-03-13 |
| FR2208657B1 (en) | 1977-01-28 |
| JPS4962480A (en) | 1974-06-17 |
| ES418666A1 (en) | 1976-02-16 |
| US3828056A (en) | 1974-08-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1489280A (en) | Indazole derivatives | |
| ES342185A1 (en) | N,n'-diglycidyl hydantoins | |
| GB1248324A (en) | Pyridoxine alpha-ketoglutarate and derivatives thereof | |
| GB1364106A (en) | Phenoxyalkylamines process for their preparation and applications thereof | |
| GB1386210A (en) | 2-methyl-5 nitro-1- 2-heteroaryloxy-ethyl imidazoles | |
| GB1395802A (en) | Substituted benzamides and herbicidal uses thereof | |
| GB1164108A (en) | Desglucohellebrin Derivatives | |
| GB1363267A (en) | Phenoxyalkylamines process for their preparation and applications | |
| GB1418619A (en) | 3,4-dihydro-2-h-naphthalin-1-one-5-oxypropyl-piperazine derivatives | |
| GB1316359A (en) | Diglycidyl derivatives of compounds containing two n-heterocyclic rings processes for their manufacture and use | |
| ES273438A1 (en) | Phenoxypropylguanidine compounds | |
| GB1181322A (en) | Piperazine Derivatives and processes for preparing the same | |
| GB1207930A (en) | Azacycloaliphatic compounds, process for their manufacture and compositions containing them | |
| GB1317179A (en) | Diglycidyl derivatives of n-heterocyclic compounds processes for their manufacute and use | |
| GB1369386A (en) | Glycidyl-urethane compounds processes for their manufacture and their use | |
| GB1459518A (en) | Process for the preparation of bicyclo 4,3,0-nonenols | |
| GB1116308A (en) | Novels-triazolo[3,4-a]isoquinolines and the preparation thereof | |
| GB1313945A (en) | Process for the manufacture of n-glycidyl-n-beta-methylglycidyl compounds | |
| GB1477561A (en) | 5,6,11,12-tetraselenotetracene-o-chloroanil complexes | |
| GB1510075A (en) | Acid addition salt of a substituted pyrido-dioxin derivative | |
| GB1032268A (en) | New guanyl-hydrazones and preparations containing them | |
| GB1318932A (en) | 20-acyl-oxy-delta16-pregnene compounds process for their production and compositions containing same | |
| GB1214188A (en) | Novel phosphorothiolates | |
| GB1325944A (en) | Bisoxalic acid diamides | |
| GB1444967A (en) | Pyrocatechol ethers |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |