GB1383432A - Method of and apparatus for growing a microorganism and carrying out fermentation - Google Patents
Method of and apparatus for growing a microorganism and carrying out fermentationInfo
- Publication number
- GB1383432A GB1383432A GB215672A GB215672A GB1383432A GB 1383432 A GB1383432 A GB 1383432A GB 215672 A GB215672 A GB 215672A GB 215672 A GB215672 A GB 215672A GB 1383432 A GB1383432 A GB 1383432A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ascending
- liquid medium
- head chamber
- head
- gas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000855 fermentation Methods 0.000 title abstract 3
- 230000004151 fermentation Effects 0.000 title abstract 3
- 244000005700 microbiome Species 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 230000001174 ascending effect Effects 0.000 abstract 7
- 239000007788 liquid Substances 0.000 abstract 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- 229920001131 Pulp (paper) Polymers 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000005192 partition Methods 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 230000001902 propagating effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
- C12M29/08—Air lift
Landscapes
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
1383432 Circulation in defined paths L A A LEFRANCOIS 17 Jan 1972 [20 Jan 1971] 2156/72 Heading B1C [Also in Division C6] In the propagation of micro-organisms and production of substances by fermentation in apparatus consisting essentially of an ascending head, a descending head and provision for agitating the liquid medium by insufflating a stream of gas into the lower portion of the ascending head chamber, the ascending head chamber has a lower portion 1, Fig. 1 of restricted cross-sectional area and an upper portion 2 which increases regularly in width. The apparatus may be employed for aerobically propagating yeast on neutralized desulphitized bisulphite liquor from a paper pulp mill. The enclosed apparatus of Fig. 5 is suitable for an ethanolic fermentation by yeast wherein the. requisite agitation is achieved by re-injecting part of the carbon dioxide produced into the lower portion of the ascending head chamber 17 through line 22. Apparatus of the form depicted in Fig. 3, in which the chambers are disposed externally of each other, may, for example, be used for growing yeast on normal paraffins. The following preferred features are disclosed: The orifices through which the insufflation gas is introduced are 1 sq. inch in cross-section with a spacing of the order of 4 inches (10 cm.). The rate of penetration of the insufflation gas into the liquid medium ranges from 10 to 40 metres/sec. A centripetal accelerator may assist the insufflation of gas. The cross-sectional area of the ascending head chamber at the top. is up to 5 or 6 times larger than at the bottom. The rate of flow of liquid medium at the end of the ascending head and through the descending head is kept at a value higher than 0.2-0.5 metres/sec. The volume of the chambers may be reduced by the interpositioning of solid bodies, see 25 on Fig. 3. The liquid medium may make roughly 1-3 revolutions of the apparatus per minute. The temperature of the liquid medium is regulated by use of hollow partitions within which cold water is circulated, see Fig. 7 on Fig. 2 and 15 on Fig. 4. These may bear on the bottom of the apparatus to strengthen the structure. The number of ascending head chamber(s) in the apparatus may differ from the number of descending head chamber(s).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7101774A FR2122689A5 (en) | 1971-01-20 | 1971-01-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1383432A true GB1383432A (en) | 1974-02-12 |
Family
ID=9070555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB215672A Expired GB1383432A (en) | 1971-01-20 | 1972-01-17 | Method of and apparatus for growing a microorganism and carrying out fermentation |
Country Status (5)
| Country | Link |
|---|---|
| DE (1) | DE2202445C3 (en) |
| FR (1) | FR2122689A5 (en) |
| GB (1) | GB1383432A (en) |
| IT (1) | IT949666B (en) |
| SU (1) | SU606553A3 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2433266A (en) * | 2005-12-16 | 2007-06-20 | Kevin Andrew Auton | Cell culture vessel |
| ITUB20153722A1 (en) * | 2015-09-18 | 2017-03-18 | Eni Spa | Reaction device with internal Air-Lift type circulation and fermentation process using said device |
| US10661232B2 (en) * | 2014-11-12 | 2020-05-26 | Eni S.P.A. | Reaction device with air-lift type internal circulation |
| US11434461B2 (en) * | 2018-03-20 | 2022-09-06 | Keck Graduate Institute Of Applied Life Sciences | Airlift perfusion bioreactor for the culture of cells |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1008963B (en) * | 1974-03-01 | 1976-11-30 | Co Tecnica Ind Petro Li Spa | IMPROVEMENT IN FERMENTERS WITH AIR DRAG |
| JPS5840463B2 (en) * | 1977-08-11 | 1983-09-06 | 鐘淵化学工業株式会社 | High bacterial cell concentration culture method for yeast |
-
1971
- 1971-01-20 FR FR7101774A patent/FR2122689A5/fr not_active Expired
-
1972
- 1972-01-17 GB GB215672A patent/GB1383432A/en not_active Expired
- 1972-01-18 IT IT4778772A patent/IT949666B/en active
- 1972-01-19 DE DE19722202445 patent/DE2202445C3/en not_active Expired
- 1972-01-20 SU SU721740901A patent/SU606553A3/en active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2433266A (en) * | 2005-12-16 | 2007-06-20 | Kevin Andrew Auton | Cell culture vessel |
| EP2025391A1 (en) | 2005-12-16 | 2009-02-18 | Cellexus Limited | Cell culture and mixing vessel with gaz circulation |
| US10661232B2 (en) * | 2014-11-12 | 2020-05-26 | Eni S.P.A. | Reaction device with air-lift type internal circulation |
| ITUB20153722A1 (en) * | 2015-09-18 | 2017-03-18 | Eni Spa | Reaction device with internal Air-Lift type circulation and fermentation process using said device |
| WO2017046720A1 (en) * | 2015-09-18 | 2017-03-23 | Eni S.P.A. | Reaction device with air-lift type internal circulation and fermentation process using said device |
| CN108026497A (en) * | 2015-09-18 | 2018-05-11 | 埃尼股份公司 | With the reaction unit of circulation inside gas lift type and the fermentation process using described device |
| US11434461B2 (en) * | 2018-03-20 | 2022-09-06 | Keck Graduate Institute Of Applied Life Sciences | Airlift perfusion bioreactor for the culture of cells |
Also Published As
| Publication number | Publication date |
|---|---|
| SU606553A3 (en) | 1978-05-05 |
| DE2202445B2 (en) | 1977-10-20 |
| DE2202445C3 (en) | 1978-06-08 |
| FR2122689A5 (en) | 1972-09-01 |
| IT949666B (en) | 1973-06-11 |
| DE2202445A1 (en) | 1972-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |