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GB1379532A - 5,6,7,8-tetrahydrofolic acid crystal and process of producing the crystal - Google Patents

5,6,7,8-tetrahydrofolic acid crystal and process of producing the crystal

Info

Publication number
GB1379532A
GB1379532A GB2220273A GB2220273A GB1379532A GB 1379532 A GB1379532 A GB 1379532A GB 2220273 A GB2220273 A GB 2220273A GB 2220273 A GB2220273 A GB 2220273A GB 1379532 A GB1379532 A GB 1379532A
Authority
GB
United Kingdom
Prior art keywords
crystal
tetrahydrofolic acid
producing
water
crystals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2220273A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YAMONOUCHI PHARMACEUTICAL CO L
Original Assignee
YAMONOUCHI PHARMACEUTICAL CO L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by YAMONOUCHI PHARMACEUTICAL CO L filed Critical YAMONOUCHI PHARMACEUTICAL CO L
Publication of GB1379532A publication Critical patent/GB1379532A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1379532 Preparation of the crystals of 5,6,7,8- tetrahydrofolic acid YAMANOUCHI PHARMACEUTICAL CO Ltd 9 May 1973 [12 May 1972] 22202/73 Heading C2C Crystals of 5,6,7,8-tetrahydrofolic acid are prepared by contacting anaerobically amorphous 5,6,7,8-tetrahydrofolic acid with water. The amorphous acid is preferably brought into contact with water by suspending it in water or an aqueous solvent.
GB2220273A 1972-05-12 1973-05-09 5,6,7,8-tetrahydrofolic acid crystal and process of producing the crystal Expired GB1379532A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4693672A JPS497416A (en) 1972-05-12 1972-05-12

Publications (1)

Publication Number Publication Date
GB1379532A true GB1379532A (en) 1975-01-02

Family

ID=12761189

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2220273A Expired GB1379532A (en) 1972-05-12 1973-05-09 5,6,7,8-tetrahydrofolic acid crystal and process of producing the crystal

Country Status (4)

Country Link
JP (1) JPS497416A (en)
DE (1) DE2323124A1 (en)
FR (1) FR2184718B1 (en)
GB (1) GB1379532A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2165422C2 (en) * 1994-05-09 2001-04-20 Эпрова АГ Stable crystalline 6(s)- or 6(r)-tetrahydrofolic acid, methods of their preparing and pharmaceutical composition

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH695217A5 (en) * 1999-07-14 2006-01-31 Merck Eprova Ag A process for separation of optical isomers of tetrahydrofolic acid esters and salts tetrahydrofolic acid.
DE202024101025U1 (en) 2024-03-01 2024-06-28 Willy Lutz Built pallet

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2165422C2 (en) * 1994-05-09 2001-04-20 Эпрова АГ Stable crystalline 6(s)- or 6(r)-tetrahydrofolic acid, methods of their preparing and pharmaceutical composition
US6596721B2 (en) 1994-05-09 2003-07-22 Eprova Ag Stable crystalline (6R) -tetrahydrofolic acid

Also Published As

Publication number Publication date
FR2184718B1 (en) 1977-04-29
FR2184718A1 (en) 1973-12-28
DE2323124A1 (en) 1973-11-22
JPS497416A (en) 1974-01-23

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees