GB1360560A - Process for the preparation of 3-benzoylphenyl alkanoic acids - Google Patents
Process for the preparation of 3-benzoylphenyl alkanoic acidsInfo
- Publication number
- GB1360560A GB1360560A GB5564072A GB5564072A GB1360560A GB 1360560 A GB1360560 A GB 1360560A GB 5564072 A GB5564072 A GB 5564072A GB 5564072 A GB5564072 A GB 5564072A GB 1360560 A GB1360560 A GB 1360560A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- benzoylphenyl
- alkanoic acids
- dec
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 4
- 150000007513 acids Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- -1 3-benzoylphenyl Chemical group 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 150000002825 nitriles Chemical class 0.000 abstract 2
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000005171 halobenzenes Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1360560 Preparation of 3-benzoylphenylalkanoic acids RHONE-POULENC SA 1 Dec 1972 [3 Dec 1971 16 Oct 1972] 55640/72 Heading C2C Compounds XV in which R 4 is H or halo, and R 3 is H or CH 3 are prepared by Friedel-Crafts reaction of a nitrile XVI and benzene or a halobenzene to give a nitrile XVII which is then hydrolysed. The free acid may be converted to a salt by methods known per se. The starting material XVI is prepared by reaction of SOCl 2 with the appropriate acid.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7143565A FR2163875A5 (en) | 1971-12-03 | 1971-12-03 | 3-benzoylphenyl acetic and 2-(3-benzoyl phenyl) - propionic acids prepn - for use as anti-inflammatories |
| FR7236570A FR2202873A2 (en) | 1972-10-16 | 1972-10-16 | 3-benzoylphenyl acetic and 2-(3-benzoyl phenyl) - propionic acids prepn - for use as anti-inflammatories |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1360560A true GB1360560A (en) | 1974-07-17 |
Family
ID=26216758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5564072A Expired GB1360560A (en) | 1971-12-03 | 1972-12-01 | Process for the preparation of 3-benzoylphenyl alkanoic acids |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS528301B2 (en) |
| AR (1) | AR194864A1 (en) |
| AT (1) | AT321283B (en) |
| BE (1) | BE792218A (en) |
| CA (1) | CA972765A (en) |
| CH (1) | CH545761A (en) |
| CS (1) | CS170457B2 (en) |
| CY (1) | CY916A (en) |
| DD (1) | DD100239A5 (en) |
| DE (1) | DE2258985C2 (en) |
| DK (1) | DK134814B (en) |
| ES (1) | ES409237A1 (en) |
| FI (1) | FI55173C (en) |
| GB (1) | GB1360560A (en) |
| HK (1) | HK60177A (en) |
| HU (1) | HU166290B (en) |
| IE (1) | IE36936B1 (en) |
| IL (1) | IL40972A (en) |
| LU (1) | LU66586A1 (en) |
| NL (1) | NL7215990A (en) |
| NO (1) | NO139782C (en) |
| OA (1) | OA04219A (en) |
| PL (1) | PL77271B1 (en) |
| SE (1) | SE397675B (en) |
| SU (1) | SU457210A3 (en) |
| YU (1) | YU36003B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4340740A (en) | 1979-07-16 | 1982-07-20 | Sagami Chemical Research Center | Alpha-thio-alpha-aryl-substituted alkanonitrile and process for preparing alpha-aryl-substituted alkanonitrile therefrom |
| AU574129B2 (en) * | 1984-01-19 | 1988-06-30 | Pharmacia Ab | Arylacetic acid derivatives |
| ES2163986A1 (en) * | 1999-07-13 | 2002-02-01 | Menarini Lab | Set of inflammation and pain inhibitors for e.g. cyclooxygenase activity inhibitors comprises alpha aryl propionic acids and aryl acetic acids |
| CN111675631A (en) * | 2020-06-24 | 2020-09-18 | 湖北仙盛科技股份有限公司 | Synthesis process of cyano ketoprofen |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS582934B2 (en) * | 1974-07-29 | 1983-01-19 | ニツシンセイフン カブシキガイシヤ | Process for producing 2-(substituted aryl)-propionic acid |
| DE2708142C3 (en) * | 1977-02-25 | 1981-10-29 | Rütgerswerke AG, 6000 Frankfurt | Process for the preparation of substituted phenylacetonitriles and new phenylacetonitriles |
| ES2058024B1 (en) * | 1992-11-10 | 1995-05-01 | Menarini Lab | NEW ARILPROPIONIC DERIVATIVE, MANUFACTURING PROCEDURE OF THE SAME AND ITS USE AS AN ANALGESIC. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1546478A (en) * | 1967-01-27 | 1968-11-22 | Rhone Poulenc Sa | New derivatives of 3-benzoylphenylacetic acid and their preparation |
| GB1226344A (en) * | 1967-07-31 | 1971-03-24 |
-
1972
- 1972-11-22 OA OA54753A patent/OA04219A/en unknown
- 1972-11-24 NL NL7215990A patent/NL7215990A/xx unknown
- 1972-11-30 IL IL40972A patent/IL40972A/en unknown
- 1972-11-30 IE IE1660/72A patent/IE36936B1/en unknown
- 1972-11-30 JP JP47119468A patent/JPS528301B2/ja not_active Expired
- 1972-12-01 GB GB5564072A patent/GB1360560A/en not_active Expired
- 1972-12-01 DD DD167245A patent/DD100239A5/xx unknown
- 1972-12-01 DE DE2258985A patent/DE2258985C2/en not_active Expired
- 1972-12-01 CA CA158,010A patent/CA972765A/en not_active Expired
- 1972-12-01 AT AT1022772A patent/AT321283B/en active
- 1972-12-01 PL PL1972159227A patent/PL77271B1/en unknown
- 1972-12-01 NO NO4425/72A patent/NO139782C/en unknown
- 1972-12-01 BE BE792218D patent/BE792218A/en not_active IP Right Cessation
- 1972-12-01 CS CS8228A patent/CS170457B2/cs unknown
- 1972-12-01 FI FI3415/72A patent/FI55173C/en active
- 1972-12-01 HU HURO687A patent/HU166290B/hu unknown
- 1972-12-01 LU LU66586A patent/LU66586A1/xx unknown
- 1972-12-01 AR AR245440A patent/AR194864A1/en active
- 1972-12-01 YU YU2990/72A patent/YU36003B/en unknown
- 1972-12-01 SU SU1859757A patent/SU457210A3/en active
- 1972-12-01 CH CH1756172A patent/CH545761A/xx not_active IP Right Cessation
- 1972-12-01 CY CY916A patent/CY916A/en unknown
- 1972-12-01 SE SE7215722A patent/SE397675B/en unknown
- 1972-12-01 DK DK602072AA patent/DK134814B/en not_active IP Right Cessation
- 1972-12-02 ES ES409237A patent/ES409237A1/en not_active Expired
-
1977
- 1977-12-01 HK HK601/77A patent/HK60177A/en unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4340740A (en) | 1979-07-16 | 1982-07-20 | Sagami Chemical Research Center | Alpha-thio-alpha-aryl-substituted alkanonitrile and process for preparing alpha-aryl-substituted alkanonitrile therefrom |
| AU574129B2 (en) * | 1984-01-19 | 1988-06-30 | Pharmacia Ab | Arylacetic acid derivatives |
| ES2163986A1 (en) * | 1999-07-13 | 2002-02-01 | Menarini Lab | Set of inflammation and pain inhibitors for e.g. cyclooxygenase activity inhibitors comprises alpha aryl propionic acids and aryl acetic acids |
| CN111675631A (en) * | 2020-06-24 | 2020-09-18 | 湖北仙盛科技股份有限公司 | Synthesis process of cyano ketoprofen |
Also Published As
| Publication number | Publication date |
|---|---|
| NO139782B (en) | 1979-01-29 |
| CH545761A (en) | 1974-02-15 |
| SE397675B (en) | 1977-11-14 |
| DK134814B (en) | 1977-01-24 |
| JPS4864059A (en) | 1973-09-05 |
| IE36936L (en) | 1973-06-03 |
| IE36936B1 (en) | 1977-03-30 |
| ES409237A1 (en) | 1975-12-01 |
| NL7215990A (en) | 1973-06-05 |
| DE2258985C2 (en) | 1982-07-01 |
| DD100239A5 (en) | 1973-09-12 |
| YU36003B (en) | 1981-11-13 |
| IL40972A (en) | 1976-03-31 |
| OA04219A (en) | 1979-12-31 |
| AR194864A1 (en) | 1973-08-24 |
| DK134814C (en) | 1977-06-13 |
| IL40972A0 (en) | 1973-01-30 |
| BE792218A (en) | 1973-06-01 |
| LU66586A1 (en) | 1973-07-18 |
| PL77271B1 (en) | 1975-04-30 |
| CS170457B2 (en) | 1976-08-27 |
| DE2258985A1 (en) | 1973-06-14 |
| HK60177A (en) | 1977-12-09 |
| CY916A (en) | 1977-12-23 |
| CA972765A (en) | 1975-08-12 |
| FI55173C (en) | 1979-06-11 |
| JPS528301B2 (en) | 1977-03-08 |
| YU299072A (en) | 1981-02-28 |
| SU457210A3 (en) | 1975-01-15 |
| NO139782C (en) | 1979-05-09 |
| AT321283B (en) | 1975-03-25 |
| FI55173B (en) | 1979-02-28 |
| HU166290B (en) | 1975-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 746B | Proceeding under section 46(3) patents act 1977 | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19921130 |