GB1356094A - Pharmaceutical and veterinary compositions for the treatment of hyperlipoproteinaemia - Google Patents
Pharmaceutical and veterinary compositions for the treatment of hyperlipoproteinaemiaInfo
- Publication number
- GB1356094A GB1356094A GB5570472A GB5570472A GB1356094A GB 1356094 A GB1356094 A GB 1356094A GB 5570472 A GB5570472 A GB 5570472A GB 5570472 A GB5570472 A GB 5570472A GB 1356094 A GB1356094 A GB 1356094A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hyperlipoproteinaemia
- pharmaceutical
- treatment
- composition
- veterinary compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000031226 Hyperlipidaemia Diseases 0.000 title abstract 2
- ONIKNECPXCLUHT-UHFFFAOYSA-N 2-chlorobenzoyl chloride Chemical compound ClC(=O)C1=CC=CC=C1Cl ONIKNECPXCLUHT-UHFFFAOYSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-M 3-carboxy-2,3-dihydroxypropanoate Chemical class OC(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-M 0.000 abstract 1
- MVQVNTPHUGQQHK-UHFFFAOYSA-N 3-pyridinemethanol Chemical compound OCC1=CC=CN=C1 MVQVNTPHUGQQHK-UHFFFAOYSA-N 0.000 abstract 1
- 229910018626 Al(OH) Inorganic materials 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1356094 Pharmaceutical composition MERCK PATENT GmbH 1 Dec 1972 [11 Dec 1971] 55704/72 Heading A5B A composition for treating hyperlipoproteinaemia comprises (a) 50 mols of a compound of formula R<SP>1</SP> is H, C 1-6 alkyl, one valence of a monodi- or trivalent cation or -Al(OH)OCOC(CH 3 ) 2 OC 6 H 4 pCl and (b) 1-25 mols of 3-pyridylcarbinol or a salt thereof. In specific Examples, R' is H, sodium, calcium, methyl or propyl and (b) is present as its bitartrate salt. The composition may be made up as a tablet, capsule, suppository, dragee, syrup or elixir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2161588A DE2161588C3 (en) | 1971-12-11 | 1971-12-11 | Agents for the treatment of hyperlipoproteinemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1356094A true GB1356094A (en) | 1974-06-12 |
Family
ID=5827712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5570472A Expired GB1356094A (en) | 1971-12-11 | 1972-12-01 | Pharmaceutical and veterinary compositions for the treatment of hyperlipoproteinaemia |
Country Status (14)
| Country | Link |
|---|---|
| AT (1) | AT327373B (en) |
| AU (1) | AU466300B2 (en) |
| BE (1) | BE792421A (en) |
| BR (1) | BR7208624D0 (en) |
| CA (1) | CA989307A (en) |
| DD (1) | DD102583A5 (en) |
| DE (1) | DE2161588C3 (en) |
| FR (1) | FR2162493B1 (en) |
| GB (1) | GB1356094A (en) |
| HU (1) | HU167337B (en) |
| IL (1) | IL40912A (en) |
| MY (1) | MY7700129A (en) |
| NL (1) | NL159579B (en) |
| ZA (1) | ZA728251B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820739A (en) * | 1982-06-28 | 1989-04-11 | Lucta, S.A. | Fat suppressant |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2502678C3 (en) * | 1975-01-23 | 1981-05-14 | Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren | Medicines used to treat primary and secondary hyperlipoproteinaemia |
| DE2621873C3 (en) | 1976-05-17 | 1981-05-07 | Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren | Medicines used to treat hypercholesterolaemia |
| FR2430229A1 (en) * | 1978-01-16 | 1980-02-01 | Laruelle Claude | Hypolipoproteinaemic, hypocholesterolaemic, hypolipaemic compsn. - contains synergistic mixt. of 2-methyl 2-4-halo-benzoyl-phenoxy-propionic acid ester and 3-pyridyl-methanol |
| US4859703A (en) * | 1987-06-15 | 1989-08-22 | Warner-Lambert Company | Lipid regulating compositions |
-
0
- BE BE792421D patent/BE792421A/en unknown
-
1971
- 1971-12-11 DE DE2161588A patent/DE2161588C3/en not_active Expired
-
1972
- 1972-11-21 ZA ZA728251A patent/ZA728251B/en unknown
- 1972-11-24 IL IL40912A patent/IL40912A/en unknown
- 1972-12-01 GB GB5570472A patent/GB1356094A/en not_active Expired
- 1972-12-06 FR FR7243400A patent/FR2162493B1/fr not_active Expired
- 1972-12-07 BR BR8624/72A patent/BR7208624D0/en unknown
- 1972-12-08 DD DD167405A patent/DD102583A5/xx unknown
- 1972-12-08 HU HUME1573A patent/HU167337B/hu unknown
- 1972-12-11 NL NL7216788.A patent/NL159579B/en not_active IP Right Cessation
- 1972-12-11 AT AT1049172A patent/AT327373B/en not_active IP Right Cessation
- 1972-12-11 CA CA158,568A patent/CA989307A/en not_active Expired
- 1972-12-11 AU AU49918/72A patent/AU466300B2/en not_active Expired
-
1977
- 1977-12-30 MY MY129/77A patent/MY7700129A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820739A (en) * | 1982-06-28 | 1989-04-11 | Lucta, S.A. | Fat suppressant |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2161588B2 (en) | 1976-05-26 |
| BR7208624D0 (en) | 1973-09-20 |
| CA989307A (en) | 1976-05-18 |
| NL7216788A (en) | 1973-06-13 |
| IL40912A (en) | 1975-11-25 |
| ZA728251B (en) | 1973-07-25 |
| MY7700129A (en) | 1977-12-31 |
| DE2161588C3 (en) | 1980-02-14 |
| ATA1049172A (en) | 1975-04-15 |
| NL159579B (en) | 1979-03-15 |
| FR2162493A1 (en) | 1973-07-20 |
| BE792421A (en) | 1973-06-07 |
| IL40912A0 (en) | 1973-01-30 |
| AU4991872A (en) | 1974-06-13 |
| AT327373B (en) | 1976-01-26 |
| HU167337B (en) | 1975-09-27 |
| AU466300B2 (en) | 1975-10-23 |
| DE2161588A1 (en) | 1973-06-20 |
| FR2162493B1 (en) | 1975-06-20 |
| DD102583A5 (en) | 1973-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |