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GB1353481A - Determination of coagulation characteristics of blood - Google Patents

Determination of coagulation characteristics of blood

Info

Publication number
GB1353481A
GB1353481A GB1038571*[A GB1038571A GB1353481A GB 1353481 A GB1353481 A GB 1353481A GB 1038571 A GB1038571 A GB 1038571A GB 1353481 A GB1353481 A GB 1353481A
Authority
GB
United Kingdom
Prior art keywords
vessel
blood
coagulation
sample
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1038571*[A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hellige Co Fritz GmbH
Original Assignee
Hellige Co Fritz GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hellige Co Fritz GmbH filed Critical Hellige Co Fritz GmbH
Publication of GB1353481A publication Critical patent/GB1353481A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/16—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

1353481 Agitating liquids; controlling mixing by viscosity FRITZ HELLIGE & CO GmbH 21 April 1971 [22 April 1970] 10385/71 Heading BIC [Also in Division G1] A device for determining the coagulation characteristics of blood in vitro comprises a vessel 5 for the blood sample, coagulation detecting means part of which (probe 1 in the embodiment shown) is mounted for at least partial immersion in the blood sample, means to impart to the vessel a rotary oscillation about the at least partly immersed part of the detecting means and means to superimpose on to the rotary oscillation a precessional movement of the vessel around the at least partly immersed part of the detecting means to simullate the natural flow of blood in vivo. In the device shown (Fig. 5), vessel 5 containing the sample is mounted in opening 26 in crank lever 27, lever 27 having projection 28 which both slides along and pivots on straight edge 29a when lever 27 is moved by cam 33 eccentrically mounted on motor 32, producing a circular precession movement of vessel 5 around probe 1 which is immersed in the sample. The rotary oscillation is provided (Fig. 2) by motor 9 and a crank mechanism (Fig. 1, not shown). The oscillation of the probe suspension may be detected visually as when a light beam from a source 10 is reflected from mirror 4 carried by the suspension device and is deflected on to ground glass screen 14, or photographically, when mirror 11 is turned out of the path of the light beam and reflected light falls on photographic recording tape 19. It is stated that the means for simulating the natural flow of blood in vivo may be used in simple measuring devices for determination of clotting time and in other methods for investigation of coagulation by electrical, optical, chemical or mechanical means other than those described.
GB1038571*[A 1970-04-22 1971-04-21 Determination of coagulation characteristics of blood Expired GB1353481A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2019341A DE2019341C3 (en) 1970-04-22 1970-04-22 Device for simulating flow effects in a coagulating liquid, in particular in blood

Publications (1)

Publication Number Publication Date
GB1353481A true GB1353481A (en) 1974-05-15

Family

ID=5768782

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1038571*[A Expired GB1353481A (en) 1970-04-22 1971-04-21 Determination of coagulation characteristics of blood

Country Status (8)

Country Link
US (1) US3714815A (en)
JP (1) JPS5434360B1 (en)
CH (1) CH535957A (en)
DE (1) DE2019341C3 (en)
FR (1) FR2089651A5 (en)
GB (1) GB1353481A (en)
NL (1) NL7104868A (en)
SE (1) SE381342B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2223853A (en) * 1988-10-04 1990-04-18 Plint & Partners Ltd Viscometer and method of measuring viscosity
DE4437475C1 (en) * 1994-10-19 1996-04-04 Andreas Calatzis Coagulation characteristics measuring device for blood sample
DE19542225A1 (en) * 1995-11-01 1997-05-07 Buero Fuer Biomedizinische Ing Method and device for determining rheological and mechanical parameters
US5777215A (en) * 1994-10-19 1998-07-07 Calatzis; Alexander Apparatus for measuring the coagulation characteristics of test liquids
WO2014043251A1 (en) * 2012-09-11 2014-03-20 Board Of Regents The University Of Texas System Blood coagulometer and method
US10295554B2 (en) * 2015-06-29 2019-05-21 C A Casyso Gmbh Blood testing system and method

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2383444A1 (en) * 1977-03-11 1978-10-06 Laborgeraete Analysensyst Gmbh MEASURING BLOOD COAGULATION TIME
IT1076740B (en) * 1977-04-28 1985-04-27 E L V I Spa BLOOD ELASTICITY PARAMETER DETERMINATION EQUIPMENT
DE2741060C2 (en) * 1977-09-13 1982-06-24 Chemisch-pharmazeutische Industrie KG 6380 Bad Homburg Dr. Eduard Fresenius Method and device for detecting the change in state of a liquid
US4148216A (en) * 1978-01-18 1979-04-10 Do Mau T Apparatus for determining the viscous behavior of a liquid during coagulation thereof
DE2908469A1 (en) * 1979-03-05 1980-09-11 Fresenius Chem Pharm Ind METHOD AND DEVICE FOR DETERMINING THE VISCO-ELASTIC PROPERTIES OF FLUIDS
FR2455273A2 (en) * 1979-04-27 1980-11-21 Probio Dms IMPROVEMENTS TO THROMBOELASTOGRAPHY DEVICES
US4317363A (en) * 1980-06-16 1982-03-02 Abbott Laboratories Elastomer instrument
FR2535052A1 (en) * 1982-10-25 1984-04-27 Agronomique Inst Nat Rech METHOD AND APPARATUS FOR MEASURING THE RHEOLOGICAL PROPERTIES OF SEMI-SOLID BODIES BY HARMONIC SHEAR IN ROTATION
FR2566908B1 (en) * 1984-06-27 1986-07-18 Girolami Antoine COAGULOMETER AND METHOD FOR MEASURING THE COAGULATION TIME OF SAMPLES OF FLUID PRODUCTS
GB8720377D0 (en) * 1987-08-28 1987-10-07 Shell Int Research Journal bearing simulator
DE3918533C2 (en) * 1989-06-07 1997-12-04 Hartert Geb Klug Elisabeth Method for determining the coagulation properties of coagulating liquids such as blood or blood plasma
US6225126B1 (en) * 1999-02-22 2001-05-01 Haemoscope Corporation Method and apparatus for measuring hemostasis
US7732213B2 (en) * 1999-02-22 2010-06-08 Coramed Healthcare, Inc. Method of evaluating patient hemostasis
US8008086B2 (en) * 1999-02-22 2011-08-30 Cora Healthcare, Inc. Protocol for monitoring direct thrombin inhibition
US7179652B2 (en) * 1999-02-22 2007-02-20 Haemoscope Corporation Protocol for monitoring platelet inhibition
DE19939252A1 (en) * 1999-08-16 2001-04-19 Volker Goltz Apparatus for testing blood samples has a reaction vessel with limited surfaces forming a reaction zone for blood platelets to adhere to a reaction surface for reactions to be examined
US7524670B2 (en) * 2003-08-05 2009-04-28 Haemoscope Corporation Protocol and apparatus for determining heparin-induced thrombocytopenia
US7745223B2 (en) * 2004-08-12 2010-06-29 C A Casyso Ag Device with novel and improved surface properties
GB0418474D0 (en) 2004-08-12 2004-09-22 Pentapharm Ltd Device with novel and improved surface properties
GB2444956A (en) 2006-12-19 2008-06-25 Pentapharm Ag An apparatus and method for measuring the coagulation characteristics of a test liquid
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
EP3734274B1 (en) 2008-12-23 2025-04-23 C A Casyso GmbH System for measuring viscoelastic properties of blood
US8383045B2 (en) * 2009-01-16 2013-02-26 C A Casyso Ag Measuring unit for measuring characteristics of a sample liquid, in particular viscoelastic characteristics of a blood sample
EP2371284A1 (en) 2010-03-24 2011-10-05 C A Casyso AG Method and apparatus for determining at least one evaluation parameter of a blood sample
US10288630B2 (en) 2014-09-29 2019-05-14 C A Casyso Gmbh Blood testing system and method
US10816559B2 (en) 2014-09-29 2020-10-27 Ca Casyso Ag Blood testing system and method
US10539579B2 (en) 2014-09-29 2020-01-21 C A Casyso Gmbh Blood testing system and method
US10175225B2 (en) 2014-09-29 2019-01-08 C A Casyso Ag Blood testing system and method
US9897618B2 (en) 2014-09-29 2018-02-20 C A Casyso Gmbh Blood testing system
US10473674B2 (en) 2016-08-31 2019-11-12 C A Casyso Gmbh Controlled blood delivery to mixing chamber of a blood testing cartridge
CN110709698B (en) 2017-01-26 2021-06-01 埃尼科尔股份有限公司 Apparatus and method for measuring viscoelastic changes of a sample
US10843185B2 (en) 2017-07-12 2020-11-24 Ca Casyso Gmbh Autoplatelet cartridge device
US11781961B1 (en) 2020-03-26 2023-10-10 Rheonics Gmbh Method and device for monitoring transformation processes of fluids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1283946A (en) * 1960-12-28 1962-02-09 Device for measuring blood clotting time

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2223853A (en) * 1988-10-04 1990-04-18 Plint & Partners Ltd Viscometer and method of measuring viscosity
GB2223853B (en) * 1988-10-04 1992-08-26 Plint & Partners Ltd Viscometer and method of measuring viscosity
DE4437475C1 (en) * 1994-10-19 1996-04-04 Andreas Calatzis Coagulation characteristics measuring device for blood sample
US5777215A (en) * 1994-10-19 1998-07-07 Calatzis; Alexander Apparatus for measuring the coagulation characteristics of test liquids
DE19542225A1 (en) * 1995-11-01 1997-05-07 Buero Fuer Biomedizinische Ing Method and device for determining rheological and mechanical parameters
DE19542225B4 (en) * 1995-11-01 2011-05-26 L.U.M. Gmbh Method and device for determining rheological and mechanical substance characteristics
WO2014043251A1 (en) * 2012-09-11 2014-03-20 Board Of Regents The University Of Texas System Blood coagulometer and method
US9753024B2 (en) 2012-09-11 2017-09-05 Board Of Regents Of The University Of Texas Systems Blood coagulometer and method
US10295554B2 (en) * 2015-06-29 2019-05-21 C A Casyso Gmbh Blood testing system and method
US11085938B2 (en) 2015-06-29 2021-08-10 C A Casyso Gmbh Thromboelastometry blood testing system and accuracy control methods

Also Published As

Publication number Publication date
DE2019341A1 (en) 1971-11-04
DE2019341B2 (en) 1979-04-19
JPS5434360B1 (en) 1979-10-26
CH535957A (en) 1973-04-15
DE2019341C3 (en) 1979-12-20
US3714815A (en) 1973-02-06
SE381342B (en) 1975-12-01
FR2089651A5 (en) 1972-01-07
NL7104868A (en) 1971-10-26

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PE20 Patent expired after termination of 20 years