GB1351761A - Substituted p-menthane carboxamides and compositions containing them - Google Patents
Substituted p-menthane carboxamides and compositions containing themInfo
- Publication number
- GB1351761A GB1351761A GB392871*[A GB1351761DA GB1351761A GB 1351761 A GB1351761 A GB 1351761A GB 1351761D A GB1351761D A GB 1351761DA GB 1351761 A GB1351761 A GB 1351761A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- aliphatic radical
- optionally substituted
- substituted
- sweets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Chemical class 0.000 title abstract 2
- FINKDHKJINNQQW-UHFFFAOYSA-N 5-methyl-2-propan-2-ylcyclohexane-1-carboxamide Chemical class CC(C)C1CCC(C)CC1C(N)=O FINKDHKJINNQQW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
- 235000002899 Mentha suaveolens Nutrition 0.000 abstract 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 abstract 1
- 235000012411 boiled sweets Nutrition 0.000 abstract 1
- 235000015218 chewing gum Nutrition 0.000 abstract 1
- 229940112822 chewing gum Drugs 0.000 abstract 1
- 235000009508 confectionery Nutrition 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 235000015243 ice cream Nutrition 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
- A23G9/32—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
- A23G9/44—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor characterised by shape, structure or physical form
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/203—Alicyclic compounds
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/34—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a carbocyclic ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/14—Use of materials for tobacco smoke filters of organic materials as additive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/244—Endothermic; Cooling; Cooling sensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q9/00—Preparations for removing hair or for aiding hair removal
- A61Q9/02—Shaving preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Confectionery (AREA)
- Detergent Compositions (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Seasonings (AREA)
- Fats And Perfumes (AREA)
- Medicinal Preparation (AREA)
- Manufacture Of Tobacco Products (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Abstract
1351761 Comestible products WILKINSON SWORD Ltd 26 Jan 1972 [4 Feb 1971] 3928/71 Heading A2B [Also in Divisions A4 A5 C2 C4 C5 C6] A comestible composition comprises an edible base, a flavourant or colourant and one or more novel p-methane-3-carboxamide of the formula: wherein R' is H or C 1-25 aliphatic radical, R" is hydroxy or C 1-25 aliphatic radical, with the proviso that when R' is HR" may also be substituted phenyl, optionally substituted phenalkyl optionally substituted naphthyl or pyridyl, or R' and R" together with the nitrogen atom to which they are attached form a heterocyclic ring optionally containing further hetero atoms. The compounds may be added to boiled sweets, mint sweets, chewing gum and ice cream. The compounds are capable of stimulating the cold receptors of the nervous system of the human body.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB392871 | 1971-02-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1351761A true GB1351761A (en) | 1974-05-01 |
Family
ID=9767542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB392871*[A Expired GB1351761A (en) | 1971-02-04 | 1971-02-04 | Substituted p-menthane carboxamides and compositions containing them |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS5115098B1 (en) |
| AR (1) | AR193061A1 (en) |
| AT (1) | AT330361B (en) |
| AU (1) | AU456393B2 (en) |
| BE (1) | BE778953A (en) |
| BR (1) | BR7200575D0 (en) |
| CA (1) | CA969181A (en) |
| CH (2) | CH556822A (en) |
| DD (1) | DD100154A5 (en) |
| DE (1) | DE2205255C3 (en) |
| DK (1) | DK135305B (en) |
| EG (1) | EG10723A (en) |
| ES (1) | ES399497A1 (en) |
| FI (1) | FI55330C (en) |
| FR (1) | FR2127013B1 (en) |
| GB (1) | GB1351761A (en) |
| HK (1) | HK49978A (en) |
| HU (1) | HU165280B (en) |
| IE (1) | IE36194B1 (en) |
| IL (1) | IL38605A (en) |
| IT (1) | IT1048909B (en) |
| LU (1) | LU64729A1 (en) |
| NL (1) | NL152250B (en) |
| NO (1) | NO139218C (en) |
| SE (1) | SE397189B (en) |
| TR (1) | TR17883A (en) |
| ZA (1) | ZA72421B (en) |
Cited By (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675342A (en) * | 1979-02-02 | 1987-06-23 | The United States Of America As Represented By The Secretary Of Agriculture | Cockroach repellents |
| US5009893A (en) * | 1989-07-17 | 1991-04-23 | Warner-Lambert Company | Breath-freshening edible compositions of methol and a carboxamide |
| WO1999007235A1 (en) * | 1997-08-11 | 1999-02-18 | Warner-Lambert Company | Enhanced flavoring compositions containing n-ethyl-p-menthane-3-carboxamide and method of making and using same |
| US6277385B1 (en) | 1992-06-17 | 2001-08-21 | The Procter & Gamble Company | Cooling compositions with reduced stinging |
| WO2004037764A1 (en) * | 2002-10-28 | 2004-05-06 | Givaudan Sa | Coolant solutions and compositions comprising the sameitle |
| WO2004008871A3 (en) * | 2002-07-23 | 2005-04-21 | David Isidore Osumba | Device for orally absorbing a substance, use thereof as confectionery, tonic food, (phyto)therapeutic product and dental hygiene product and method for making such a device |
| WO2005097735A1 (en) * | 2004-04-02 | 2005-10-20 | Millennium Specialty Chemicals | Physiological cooling compositions containing highly purified ethyl ester of n-[[5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl]glycine |
| WO2005117811A2 (en) | 2004-05-28 | 2005-12-15 | Millennium Specialty Chemicals | Physiological cooling compositions |
| WO2006042150A1 (en) * | 2004-10-07 | 2006-04-20 | Vitae Pharmaceuticals, Inc. | Diaminoalkane aspartic protease inhibitors |
| WO2006092074A1 (en) * | 2005-03-01 | 2006-09-08 | Givaudan Sa | Menthane carboxamide derivatives having cooling properties |
| WO2008056119A1 (en) * | 2006-11-08 | 2008-05-15 | Paget, Hugh, Charles, Edward | N-alkylcarbonyl-d-amino hydroxyalkyl ester compounds and their use |
| WO2008151460A2 (en) | 2007-06-13 | 2008-12-18 | Givaudan Sa | Cooling compounds |
| US7588793B1 (en) | 1998-06-05 | 2009-09-15 | Cadbury Adams Usa, Llc | Enhanced flavoring compositions containing N-ethyl-p-menthane-3-carboxamide and method of making and using same |
| EP2186506A1 (en) | 2009-10-06 | 2010-05-19 | Symrise GmbH & Co. KG | Teeth cleaning compound containing menthol with reduced bitter sensation |
| EP2246323A1 (en) | 2009-04-27 | 2010-11-03 | International Flavors & Fragrances Inc. | Menthylcarboxamides and their use as cooling agents |
| US7880011B2 (en) | 2007-07-23 | 2011-02-01 | Givandan, S.A. | Amide addition reaction |
| US7893072B2 (en) | 2003-07-02 | 2011-02-22 | Genentech, Inc. | Trp-p8 active compounds and therapeutic treatment methods |
| US7955630B2 (en) | 2004-09-30 | 2011-06-07 | Kraft Foods Global Brands Llc | Thermally stable, high tensile strength encapsulated actives |
| US8097271B2 (en) | 2004-08-11 | 2012-01-17 | Kraft Foods Global Brands Llc | Warming compositions and delivery systems therefor |
| US8198453B2 (en) | 2006-09-18 | 2012-06-12 | Vitae Pharmaceuticals, Inc. | Piperidine renin inhibitors |
| US8343945B2 (en) | 2007-12-07 | 2013-01-01 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| US8362091B2 (en) | 2003-08-04 | 2013-01-29 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US8372978B2 (en) | 2009-08-06 | 2013-02-12 | Vitae Pharmaceuticals, Inc. | Salts of methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate |
| US8377422B2 (en) | 2007-12-07 | 2013-02-19 | Givaudan S.A. | Carboxamide derivatives having cooling properties |
| US8389032B2 (en) | 2005-05-23 | 2013-03-05 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition having selected particle size |
| US8435498B2 (en) | 2002-10-25 | 2013-05-07 | Foamix Ltd. | Penetrating pharmaceutical foam |
| USRE44339E1 (en) | 2003-11-21 | 2013-07-02 | Givaudan S.A. | N-substituted P-menthane carboxamides |
| US8486375B2 (en) | 2003-04-28 | 2013-07-16 | Foamix Ltd. | Foamable compositions |
| US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
| US8487130B2 (en) | 2009-04-27 | 2013-07-16 | International Flavors & Fragrances Inc. | Menthylcarboxamides and their use as cooling agents |
| US8487108B2 (en) | 2005-11-14 | 2013-07-16 | Vitae Pharmaceuticals, Inc. | Piperidinyl carbamate intermediates for the synthesis of aspartic protease inhibitors |
| US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
| US8518378B2 (en) | 2003-08-04 | 2013-08-27 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
| US8591972B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for coated active components as part of an edible composition |
| US8591974B2 (en) | 2003-11-21 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for two or more active components as part of an edible composition |
| US8591973B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for active components and a material having preselected hydrophobicity as part of an edible composition |
| US8591968B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Edible composition including a delivery system for active components |
| US8597703B2 (en) | 2005-05-23 | 2013-12-03 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component |
| CN103420867A (en) * | 2012-05-14 | 2013-12-04 | 浙江新化化工股份有限公司 | Synthesis process of novel algefacient ethyl N-[[5-methyl-2-(isopropyl)cyclohexyl]carbonyl]glycinate |
| US8618081B2 (en) | 2009-10-02 | 2013-12-31 | Foamix Ltd. | Compositions, gels and foams with rheology modulators and uses thereof |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US8664261B2 (en) | 2009-05-05 | 2014-03-04 | Givaudan S.A. | Organic compounds having cooling properties |
| US8709385B2 (en) | 2008-01-14 | 2014-04-29 | Foamix Ltd. | Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses |
| US8722021B2 (en) | 2002-10-25 | 2014-05-13 | Foamix Ltd. | Foamable carriers |
| US8795635B2 (en) | 2006-11-14 | 2014-08-05 | Foamix Ltd. | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| WO2013014235A3 (en) * | 2011-07-26 | 2014-08-28 | Givaudan Sa | Rinse-off compositions |
| US8828423B2 (en) | 2003-11-21 | 2014-09-09 | Intercontinental Great Brands Llc | Delivery system for active components as part of an edible composition having preselected tensile strength |
| US8846007B2 (en) | 2005-12-23 | 2014-09-30 | Intercontinental Great Brands Llc | Compositions providing a heating sensation for oral or dermal delivery |
| US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
| US9029415B2 (en) | 2010-06-14 | 2015-05-12 | Symrise Ag | Cooling mixtures with an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate |
| US9072667B2 (en) | 2009-07-29 | 2015-07-07 | Foamix Pharmaceuticals Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| US9167813B2 (en) | 2009-07-29 | 2015-10-27 | Foamix Pharmaceuticals Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US9320705B2 (en) | 2002-10-25 | 2016-04-26 | Foamix Pharmaceuticals Ltd. | Sensation modifying topical composition foam |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| US9446267B2 (en) | 2009-10-06 | 2016-09-20 | Symrise Ag | Products comprising a flavoring agent composition |
| US9452982B2 (en) | 2005-08-15 | 2016-09-27 | Givaudan, S.A. | Pyridinyl cyclohexanecarboxamide cooling compounds |
| US9539208B2 (en) | 2002-10-25 | 2017-01-10 | Foamix Pharmaceuticals Ltd. | Foam prepared from nanoemulsions and uses |
| US9622947B2 (en) | 2002-10-25 | 2017-04-18 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| US9884017B2 (en) | 2009-04-28 | 2018-02-06 | Foamix Pharmaceuticals Ltd. | Foamable vehicles and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| US10173966B2 (en) | 2015-06-04 | 2019-01-08 | Symrise, Inc. | Physiological cooling compounds |
| US10299999B2 (en) | 2011-02-23 | 2019-05-28 | Givaudan S.A. | Flavour composition comprising menthol and menthane carboxamides |
| US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| CN113475777A (en) * | 2021-08-17 | 2021-10-08 | 深圳东灏兴科技有限公司 | Electronic cigarette |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1471894A (en) | 1973-12-12 | 1977-04-27 | Wilkinson Sword Ltd | Compositions for application to or consumption by the body and containing a compound having a physiological cooling effect |
| ZA200709252B (en) * | 2005-03-29 | 2009-04-29 | Edward Tak Wei | N-alkylcarbonyl-amino acid ester and n-alkylcarbonyl-amino lactone compounds and their use |
| DE102006007883A1 (en) * | 2006-02-21 | 2007-08-30 | Saltigo Gmbh | Preparation of menthylamide compound, useful e.g. as a cooling agent in food industry, comprises reacting menthylhalide compound with magnesium or lithium and optionally elementary iodine, and subsequently with e.g. isocyanate compound |
| DE102006047153A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine methyl ester and an antiinflammatory agent |
| DE102006047157A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological preparations containing 2-isopropyl-5-methyl-cyclohexanecarbonyl-D-alanine methyl ester and one or more skin lightening agents against unwanted pigmentation of the skin, in particular postinflammatory hyperpigmentation |
| DE102006047162A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological preparations containing combinations of (R) -2 - [((1R, 2S, 5R) -2-isopropyl-5-methyl-cyclohexanecarbonyl) -amino] -propionic acid methyl ester and one or more sunscreen filters |
| DE102006047163A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine methyl ester and an antioxidant |
| DE102006047155A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine ethyl ester and an antioxidant |
| DE102006047159A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine ethyl ester and a filler |
| DE102006047156A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological preparations containing 2-isopropyl-5-methylcyclohexanecarbonyl-D-alanine ethyl ester and one or more skin lightening agents against unwanted pigmentation of the skin, in particular postinflammatory hyperpigmentation |
| DE102006047166A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological preparations containing 2-isopropyl-5-methyl-cyclohexanecarbonyl-D-alanine ethyl ester and one or more skin moisturizers |
| DE102006047154A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine ethyl ester and an antiinflammatory agent |
| DE102006047160A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine methyl ester and a filler |
| DE102006047164A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological preparations containing 2-isopropyl-5-methyl-cyclohexanecarbonyl-D-alanine methyl ester and one or more skin moisturizers |
| EP1913976A1 (en) * | 2006-10-18 | 2008-04-23 | Symrise GmbH & Co. KG | N-alpha-(menthane carbonyl) amino acid amides and their use as physiological coolants |
| JP6061900B2 (en) * | 2014-07-24 | 2017-01-18 | 長谷川香料株式会社 | WS-12 fine particles and cooling sensation agent composition containing the same |
| CN109851522B (en) * | 2018-12-10 | 2022-03-11 | 万华化学集团股份有限公司 | Method for preparing N-ethyl-L-menthyl formamide by inversion of N-ethyl-neo-menthyl formamide configuration |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1065767B (en) * | 1959-09-17 | Zigarettenfabrik KOSMOS G.m. b.H., Memmingen (Allgäu) | Process for mentholizing tobacco and manufacturing menthol cigarettes | |
| GB1054346A (en) * | 1964-10-01 | 1900-01-01 |
-
1971
- 1971-02-04 GB GB392871*[A patent/GB1351761A/en not_active Expired
-
1972
- 1972-01-13 EG EG19/72A patent/EG10723A/en active
- 1972-01-21 IL IL38605A patent/IL38605A/en unknown
- 1972-01-21 ZA ZA720421A patent/ZA72421B/en unknown
- 1972-01-25 IE IE96/72A patent/IE36194B1/en unknown
- 1972-01-31 CA CA133,547A patent/CA969181A/en not_active Expired
- 1972-01-31 IT IT20032/72A patent/IT1048909B/en active
- 1972-02-02 HU HUWI206A patent/HU165280B/hu unknown
- 1972-02-02 BR BR575/72*[A patent/BR7200575D0/en unknown
- 1972-02-02 FI FI267/72A patent/FI55330C/en active
- 1972-02-03 TR TR17883A patent/TR17883A/en unknown
- 1972-02-03 CH CH142174A patent/CH556822A/en not_active IP Right Cessation
- 1972-02-03 DD DD160667A patent/DD100154A5/xx unknown
- 1972-02-03 JP JP47012520A patent/JPS5115098B1/ja active Pending
- 1972-02-03 CH CH162472A patent/CH548742A/en not_active IP Right Cessation
- 1972-02-03 DK DK47872AA patent/DK135305B/en not_active IP Right Cessation
- 1972-02-03 SE SE7201259A patent/SE397189B/en unknown
- 1972-02-03 AU AU38607/72A patent/AU456393B2/en not_active Expired
- 1972-02-03 FR FR7203600A patent/FR2127013B1/fr not_active Expired
- 1972-02-04 AR AR240381A patent/AR193061A1/en active
- 1972-02-04 BE BE778953A patent/BE778953A/en not_active IP Right Cessation
- 1972-02-04 DE DE2205255A patent/DE2205255C3/en not_active Expired
- 1972-02-04 LU LU64729D patent/LU64729A1/xx unknown
- 1972-02-04 ES ES399497A patent/ES399497A1/en not_active Expired
- 1972-02-04 NL NL727201523A patent/NL152250B/en not_active IP Right Cessation
- 1972-02-04 AT AT93172*#A patent/AT330361B/en not_active IP Right Cessation
-
1974
- 1974-07-24 NO NO742701A patent/NO139218C/en unknown
-
1978
- 1978-08-31 HK HK499/78A patent/HK49978A/en unknown
Cited By (140)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675342A (en) * | 1979-02-02 | 1987-06-23 | The United States Of America As Represented By The Secretary Of Agriculture | Cockroach repellents |
| US5009893A (en) * | 1989-07-17 | 1991-04-23 | Warner-Lambert Company | Breath-freshening edible compositions of methol and a carboxamide |
| US6277385B1 (en) | 1992-06-17 | 2001-08-21 | The Procter & Gamble Company | Cooling compositions with reduced stinging |
| WO1999007235A1 (en) * | 1997-08-11 | 1999-02-18 | Warner-Lambert Company | Enhanced flavoring compositions containing n-ethyl-p-menthane-3-carboxamide and method of making and using same |
| US7588793B1 (en) | 1998-06-05 | 2009-09-15 | Cadbury Adams Usa, Llc | Enhanced flavoring compositions containing N-ethyl-p-menthane-3-carboxamide and method of making and using same |
| US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
| WO2004008871A3 (en) * | 2002-07-23 | 2005-04-21 | David Isidore Osumba | Device for orally absorbing a substance, use thereof as confectionery, tonic food, (phyto)therapeutic product and dental hygiene product and method for making such a device |
| US9320705B2 (en) | 2002-10-25 | 2016-04-26 | Foamix Pharmaceuticals Ltd. | Sensation modifying topical composition foam |
| US9713643B2 (en) | 2002-10-25 | 2017-07-25 | Foamix Pharmaceuticals Ltd. | Foamable carriers |
| US10322085B2 (en) | 2002-10-25 | 2019-06-18 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US9492412B2 (en) | 2002-10-25 | 2016-11-15 | Foamix Pharmaceuticals Ltd. | Penetrating pharmaceutical foam |
| US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
| US9539208B2 (en) | 2002-10-25 | 2017-01-10 | Foamix Pharmaceuticals Ltd. | Foam prepared from nanoemulsions and uses |
| US9622947B2 (en) | 2002-10-25 | 2017-04-18 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| US8840869B2 (en) | 2002-10-25 | 2014-09-23 | Foamix Ltd. | Body cavity foams |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US8435498B2 (en) | 2002-10-25 | 2013-05-07 | Foamix Ltd. | Penetrating pharmaceutical foam |
| US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
| US8741265B2 (en) | 2002-10-25 | 2014-06-03 | Foamix Ltd. | Penetrating pharmaceutical foam |
| US8722021B2 (en) | 2002-10-25 | 2014-05-13 | Foamix Ltd. | Foamable carriers |
| US10821077B2 (en) | 2002-10-25 | 2020-11-03 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| US11033491B2 (en) | 2002-10-25 | 2021-06-15 | Vyne Therapeutics Inc. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US8093290B2 (en) | 2002-10-28 | 2012-01-10 | Givaudan Sa | Coolant solutions and compositions comprising the same |
| WO2004037764A1 (en) * | 2002-10-28 | 2004-05-06 | Givaudan Sa | Coolant solutions and compositions comprising the sameitle |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| US8486375B2 (en) | 2003-04-28 | 2013-07-16 | Foamix Ltd. | Foamable compositions |
| US7893072B2 (en) | 2003-07-02 | 2011-02-22 | Genentech, Inc. | Trp-p8 active compounds and therapeutic treatment methods |
| US9101662B2 (en) | 2003-08-04 | 2015-08-11 | Foamix Pharmaceuticals Ltd. | Compositions with modulating agents |
| US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| US8703105B2 (en) | 2003-08-04 | 2014-04-22 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US8518378B2 (en) | 2003-08-04 | 2013-08-27 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US9050253B2 (en) | 2003-08-04 | 2015-06-09 | Foamix Pharmaceuticals Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US8362091B2 (en) | 2003-08-04 | 2013-01-29 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US9636405B2 (en) | 2003-08-04 | 2017-05-02 | Foamix Pharmaceuticals Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| USRE44339E1 (en) | 2003-11-21 | 2013-07-02 | Givaudan S.A. | N-substituted P-menthane carboxamides |
| US8591974B2 (en) | 2003-11-21 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for two or more active components as part of an edible composition |
| US8828423B2 (en) | 2003-11-21 | 2014-09-09 | Intercontinental Great Brands Llc | Delivery system for active components as part of an edible composition having preselected tensile strength |
| WO2005097735A1 (en) * | 2004-04-02 | 2005-10-20 | Millennium Specialty Chemicals | Physiological cooling compositions containing highly purified ethyl ester of n-[[5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl]glycine |
| CN102731338A (en) * | 2004-04-02 | 2012-10-17 | 瑞内森兹有限责任公司 | Physiological cooling compositions containing highly purified ethyl ester of n-[[5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl]glycine |
| US7189760B2 (en) | 2004-04-02 | 2007-03-13 | Millennium Specialty Chemicals | Physiological cooling compositions containing highly purified ethyl ester of N-[[5-methyl-2-(1-methylethyl) cyclohexyl] carbonyl]glycine |
| WO2005117811A2 (en) | 2004-05-28 | 2005-12-15 | Millennium Specialty Chemicals | Physiological cooling compositions |
| US7482378B2 (en) | 2004-05-28 | 2009-01-27 | Millenium Specialty Chemicals, Inc. | Physiological cooling compositions |
| US8101208B2 (en) | 2004-08-11 | 2012-01-24 | Kraft Foods Global Brands Llc | Sensate compositions and delivery systems therefor |
| US8097271B2 (en) | 2004-08-11 | 2012-01-17 | Kraft Foods Global Brands Llc | Warming compositions and delivery systems therefor |
| US7955630B2 (en) | 2004-09-30 | 2011-06-07 | Kraft Foods Global Brands Llc | Thermally stable, high tensile strength encapsulated actives |
| US8524295B2 (en) | 2004-09-30 | 2013-09-03 | Intercontinental Great Brands Llc | Thermally stable, high tensile strength encapsulated actives |
| CN101072561B (en) * | 2004-10-07 | 2011-05-11 | 生命医药公司 | Diaminoalkane aspartic protease inhibitors |
| US8455521B2 (en) | 2004-10-07 | 2013-06-04 | Vitae Pharmaceuticals, Inc. | Diaminoalkane aspartic protease inhibitors |
| WO2006042150A1 (en) * | 2004-10-07 | 2006-04-20 | Vitae Pharmaceuticals, Inc. | Diaminoalkane aspartic protease inhibitors |
| AU2005294123B2 (en) * | 2004-10-07 | 2009-07-02 | Vitae Pharmaceuticals, Inc. | Diaminoalkane aspartic protease inhibitors |
| AU2005294123C1 (en) * | 2004-10-07 | 2010-01-21 | Vitae Pharmaceuticals, Inc. | Diaminoalkane aspartic protease inhibitors |
| US7754737B2 (en) | 2004-10-07 | 2010-07-13 | Vitae Pharmaceuticals, Inc. | Diaminoalkane aspartic protease inhibitors |
| US7868004B2 (en) | 2005-03-01 | 2011-01-11 | Givaudan S.A. | Menthane carboxamide derivatives having cooling properties |
| WO2006092074A1 (en) * | 2005-03-01 | 2006-09-08 | Givaudan Sa | Menthane carboxamide derivatives having cooling properties |
| CN101133030B (en) * | 2005-03-01 | 2010-07-28 | 奇华顿股份有限公司 | Menthane carboxamide derivatives with cooling properties |
| US8597703B2 (en) | 2005-05-23 | 2013-12-03 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component |
| US8591973B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for active components and a material having preselected hydrophobicity as part of an edible composition |
| US8591972B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for coated active components as part of an edible composition |
| US8591968B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Edible composition including a delivery system for active components |
| US8389032B2 (en) | 2005-05-23 | 2013-03-05 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition having selected particle size |
| US10221136B2 (en) | 2005-08-15 | 2019-03-05 | Givaudan, S.A. | Pyridinyl cyclohexanecarboxamide cooling compounds |
| US9452982B2 (en) | 2005-08-15 | 2016-09-27 | Givaudan, S.A. | Pyridinyl cyclohexanecarboxamide cooling compounds |
| US11059783B2 (en) | 2005-08-15 | 2021-07-13 | Givaudan S.A. | Pyridinyl cyclohexanecarboxamide cooling compounds |
| US8487108B2 (en) | 2005-11-14 | 2013-07-16 | Vitae Pharmaceuticals, Inc. | Piperidinyl carbamate intermediates for the synthesis of aspartic protease inhibitors |
| US8846007B2 (en) | 2005-12-23 | 2014-09-30 | Intercontinental Great Brands Llc | Compositions providing a heating sensation for oral or dermal delivery |
| US8580823B2 (en) | 2006-09-18 | 2013-11-12 | Vitae Pharmaceuticals, Inc. | Piperidine renin inhibitors |
| US8198453B2 (en) | 2006-09-18 | 2012-06-12 | Vitae Pharmaceuticals, Inc. | Piperidine renin inhibitors |
| WO2008056119A1 (en) * | 2006-11-08 | 2008-05-15 | Paget, Hugh, Charles, Edward | N-alkylcarbonyl-d-amino hydroxyalkyl ester compounds and their use |
| US9682021B2 (en) | 2006-11-14 | 2017-06-20 | Foamix Pharmaceuticals Ltd. | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| US8795635B2 (en) | 2006-11-14 | 2014-08-05 | Foamix Ltd. | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| WO2008151460A2 (en) | 2007-06-13 | 2008-12-18 | Givaudan Sa | Cooling compounds |
| US7959958B2 (en) | 2007-06-13 | 2011-06-14 | Givaudan, S.A. | Cooling compounds |
| US7880011B2 (en) | 2007-07-23 | 2011-02-01 | Givandan, S.A. | Amide addition reaction |
| US9662298B2 (en) | 2007-08-07 | 2017-05-30 | Foamix Pharmaceuticals Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US11103454B2 (en) | 2007-08-07 | 2021-08-31 | Vyne Therapeutics Inc. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US10369102B2 (en) | 2007-08-07 | 2019-08-06 | Foamix Pharmaceuticals Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| US8343945B2 (en) | 2007-12-07 | 2013-01-01 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| US8377422B2 (en) | 2007-12-07 | 2013-02-19 | Givaudan S.A. | Carboxamide derivatives having cooling properties |
| US9161916B2 (en) | 2007-12-07 | 2015-10-20 | Foamix Pharmaceuticals Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| US11433025B2 (en) | 2007-12-07 | 2022-09-06 | Vyne Therapeutics Inc. | Oil foamable carriers and formulations |
| US9795564B2 (en) | 2007-12-07 | 2017-10-24 | Foamix Pharmaceuticals Ltd. | Oil-based foamable carriers and formulations |
| US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
| US9549898B2 (en) | 2007-12-07 | 2017-01-24 | Foamix Pharmaceuticals Ltd. | Oil and liquid silicone foamable carriers and formulations |
| US8900553B2 (en) | 2007-12-07 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Oil and liquid silicone foamable carriers and formulations |
| US8709385B2 (en) | 2008-01-14 | 2014-04-29 | Foamix Ltd. | Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses |
| EP2246323A1 (en) | 2009-04-27 | 2010-11-03 | International Flavors & Fragrances Inc. | Menthylcarboxamides and their use as cooling agents |
| US8487130B2 (en) | 2009-04-27 | 2013-07-16 | International Flavors & Fragrances Inc. | Menthylcarboxamides and their use as cooling agents |
| US7923577B2 (en) | 2009-04-27 | 2011-04-12 | International Flavors & Fragrances Inc. | Menthylcarboxamides and their use as cooling agents |
| US10363216B2 (en) | 2009-04-28 | 2019-07-30 | Foamix Pharmaceuticals Ltd. | Foamable vehicles and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| US10213384B2 (en) | 2009-04-28 | 2019-02-26 | Foamix Pharmaceuticals Ltd. | Foamable vehicles and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| US10588858B2 (en) | 2009-04-28 | 2020-03-17 | Foamix Pharmaceuticals Ltd. | Foamable vehicles and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| US9884017B2 (en) | 2009-04-28 | 2018-02-06 | Foamix Pharmaceuticals Ltd. | Foamable vehicles and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| US8664261B2 (en) | 2009-05-05 | 2014-03-04 | Givaudan S.A. | Organic compounds having cooling properties |
| US10092588B2 (en) | 2009-07-29 | 2018-10-09 | Foamix Pharmaceuticals Ltd. | Foamable compositions, breakable foams and their uses |
| US9072667B2 (en) | 2009-07-29 | 2015-07-07 | Foamix Pharmaceuticals Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| US10350166B2 (en) | 2009-07-29 | 2019-07-16 | Foamix Pharmaceuticals Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| US9167813B2 (en) | 2009-07-29 | 2015-10-27 | Foamix Pharmaceuticals Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| US11219631B2 (en) | 2009-07-29 | 2022-01-11 | Vyne Pharmaceuticals Inc. | Foamable compositions, breakable foams and their uses |
| US9572775B2 (en) | 2009-07-29 | 2017-02-21 | Foamix Pharmaceuticals Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| US8372978B2 (en) | 2009-08-06 | 2013-02-12 | Vitae Pharmaceuticals, Inc. | Salts of methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate |
| US8871184B2 (en) | 2009-10-02 | 2014-10-28 | Foamix Ltd. | Topical tetracycline compositions |
| US12138311B2 (en) | 2009-10-02 | 2024-11-12 | Journey Medical Corporation | Topical tetracycline compositions |
| US10137200B2 (en) | 2009-10-02 | 2018-11-27 | Foamix Pharmaceuticals Ltd. | Surfactant-free water-free foamable compositions, breakable foams and gels and their uses |
| US8618081B2 (en) | 2009-10-02 | 2013-12-31 | Foamix Ltd. | Compositions, gels and foams with rheology modulators and uses thereof |
| US10213512B2 (en) | 2009-10-02 | 2019-02-26 | Foamix Pharmaceuticals Ltd. | Topical tetracycline compositions |
| US8865139B1 (en) | 2009-10-02 | 2014-10-21 | Foamix Pharmaceuticals Ltd. | Topical tetracycline compositions |
| US10086080B2 (en) | 2009-10-02 | 2018-10-02 | Foamix Pharmaceuticals Ltd. | Topical tetracycline compositions |
| US10238746B2 (en) | 2009-10-02 | 2019-03-26 | Foamix Pharmaceuticals Ltd | Surfactant-free water-free foamable compositions, breakable foams and gels and their uses |
| US10265404B2 (en) | 2009-10-02 | 2019-04-23 | Foamix Pharmaceuticals Ltd. | Compositions, gels and foams with rheology modulators and uses thereof |
| US8992896B2 (en) | 2009-10-02 | 2015-03-31 | Foamix Pharmaceuticals Ltd. | Topical tetracycline compositions |
| US10322186B2 (en) | 2009-10-02 | 2019-06-18 | Foamix Pharmaceuticals Ltd. | Topical tetracycline compositions |
| US10029013B2 (en) | 2009-10-02 | 2018-07-24 | Foamix Pharmaceuticals Ltd. | Surfactant-free, water-free formable composition and breakable foams and their uses |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| US8945516B2 (en) | 2009-10-02 | 2015-02-03 | Foamix Pharmaceuticals Ltd. | Surfactant-free water-free foamable compositions, breakable foams and gels and their uses |
| US9675700B2 (en) | 2009-10-02 | 2017-06-13 | Foamix Pharmaceuticals Ltd. | Topical tetracycline compositions |
| US10967063B2 (en) | 2009-10-02 | 2021-04-06 | Vyne Therapeutics Inc. | Surfactant-free, water-free formable composition and breakable foams and their uses |
| US10463742B2 (en) | 2009-10-02 | 2019-11-05 | Foamix Pharmaceuticals Ltd. | Topical tetracycline compositions |
| US10517882B2 (en) | 2009-10-02 | 2019-12-31 | Foamix Pharmaceuticals Ltd. | Method for healing of an infected acne lesion without scarring |
| US10946101B2 (en) | 2009-10-02 | 2021-03-16 | Vyne Therapeutics Inc. | Surfactant-free water-free foamable compositions, breakable foams and gels and their uses |
| US10610599B2 (en) | 2009-10-02 | 2020-04-07 | Foamix Pharmaceuticals Ltd. | Topical tetracycline compositions |
| US10821187B2 (en) | 2009-10-02 | 2020-11-03 | Foamix Pharmaceuticals Ltd. | Compositions, gels and foams with rheology modulators and uses thereof |
| US10835613B2 (en) | 2009-10-02 | 2020-11-17 | Foamix Pharmaceuticals Ltd. | Compositions, gels and foams with rheology modulators and uses thereof |
| EP2364689A2 (en) | 2009-10-06 | 2011-09-14 | Symrise AG | Teeth cleaning compound containing menthol with reduced bitter sensation |
| US9446267B2 (en) | 2009-10-06 | 2016-09-20 | Symrise Ag | Products comprising a flavoring agent composition |
| EP2186506A1 (en) | 2009-10-06 | 2010-05-19 | Symrise GmbH & Co. KG | Teeth cleaning compound containing menthol with reduced bitter sensation |
| US9029415B2 (en) | 2010-06-14 | 2015-05-12 | Symrise Ag | Cooling mixtures with an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate |
| US10299999B2 (en) | 2011-02-23 | 2019-05-28 | Givaudan S.A. | Flavour composition comprising menthol and menthane carboxamides |
| WO2013014235A3 (en) * | 2011-07-26 | 2014-08-28 | Givaudan Sa | Rinse-off compositions |
| CN103420867A (en) * | 2012-05-14 | 2013-12-04 | 浙江新化化工股份有限公司 | Synthesis process of novel algefacient ethyl N-[[5-methyl-2-(isopropyl)cyclohexyl]carbonyl]glycinate |
| US10173966B2 (en) | 2015-06-04 | 2019-01-08 | Symrise, Inc. | Physiological cooling compounds |
| US11324691B2 (en) | 2016-09-08 | 2022-05-10 | Journey Medical Corporation | Compositions and methods for treating rosacea and acne |
| US10849847B2 (en) | 2016-09-08 | 2020-12-01 | Foamix Pharamaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| CN113475777A (en) * | 2021-08-17 | 2021-10-08 | 深圳东灏兴科技有限公司 | Electronic cigarette |
| CN113475777B (en) * | 2021-08-17 | 2024-05-03 | 深圳东灏兴科技有限公司 | Electronic cigarette |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1351761A (en) | Substituted p-menthane carboxamides and compositions containing them | |
| GB1353381A (en) | Substituted p-menthanes and compositions containing them | |
| GB1434728A (en) | Compositions and articles containing phospine oxides having a physiological cooling effect and phosphine oxides for use therein | |
| GB1331694A (en) | Flavouring compositions and processes | |
| GB1310329A (en) | Chewing gum compositions and candy products containing a flavour preservative | |
| GB1392851A (en) | Mercapto alcohols and esters | |
| GB1315626A (en) | Substituted p-menthanes and compositions containing them | |
| KR960702988A (en) | IMPROVED CHEWING GUM AND CANDY PRODUCTS | |
| GB1422998A (en) | Cyclohexanecarboxamides having a physiological cooling effect and compositions containing them | |
| GB1206903A (en) | Phenyl alkanols and their use as food additives | |
| GB1364596A (en) | Flavouring method and compositions | |
| BR7500719A (en) | COMPOSITION CONTAINING ISOHUMULONE SUITABLE SOLUTION TO CONFIRM FLAVORS TO FOOD OR DRINKS PROCESS FOR THE PREPARATION OF A TASTY DRINK AND DRINKS SO PREPARED | |
| GB1420909A (en) | Flavouring compositions | |
| GB1479574A (en) | Milk chocolate manufacturing | |
| GB543309A (en) | Improvements in or relating to drugs | |
| GB1411785A (en) | Ingestible topical and other compositions | |
| GB1224860A (en) | Sulphur compounds as odour and taste-modifying agents | |
| GB1424497A (en) | Polycylic lactones useful as odour-and taste-modifying agents | |
| GB1240634A (en) | Oxa-thia-bicyclo[3.3.0]-5,8-octadiene derivatives and their use as flavouring agents | |
| GB1481738A (en) | Hard candy | |
| GB1335339A (en) | Process for preparing usaturated cycloaliphatic ketones | |
| GB1525679A (en) | Cyclopentanone derivatives as flavour-and odour-modifying ingredients | |
| GB1305621A (en) | ||
| GB1517158A (en) | Baking dough compositions | |
| GB1283913A (en) | Flavouring substances prepared by reaction of heterocyclic ketones with hydrogen sulphide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |