[go: up one dir, main page]

GB1214053A - Improvements in or relating to two chamber injection ampoules - Google Patents

Improvements in or relating to two chamber injection ampoules

Info

Publication number
GB1214053A
GB1214053A GB5744/68A GB574468A GB1214053A GB 1214053 A GB1214053 A GB 1214053A GB 5744/68 A GB5744/68 A GB 5744/68A GB 574468 A GB574468 A GB 574468A GB 1214053 A GB1214053 A GB 1214053A
Authority
GB
United Kingdom
Prior art keywords
piston
plunger
ampoule
sealing
intermediate piston
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5744/68A
Inventor
Hans Wimmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB5744/68A priority Critical patent/GB1214053A/en
Publication of GB1214053A publication Critical patent/GB1214053A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7138—Opening valves which close-off openings between compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
    • B01F35/7161—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected coaxially before contacting the contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/32005—Type of drive
    • B01F35/3202—Hand driven

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

1,214,053. Two-compartment injection ampoules. H. WIMMER. 5 Feb., 1968, No. 5744/ 68. Heading A5R. Two-compartment injecton ampoules comprising an ampoule barrel adapted to receive an injection needle at one end, and having a resilient sealing piston at the other end and an intermediate piston which initially divides the ampoule into two compartments, the contents of which are mixed by moving the intermediate piston towards the sealing piston, and the ampoule contents are injected by urging both intermediate and sealing pistons down the ampoule, are characterised in having a plunger which moves the intermediate piston so that, on movement of the intermediate piston towards the sealing piston, a previously sealed channel is opened which connects the two compartments across the intermediate piston and, during injection, both pistons are movably connected and move together down the ampoule. In the embodiments illustrated in Figs. 1-10 (Figs. 2-10 not shown) the bore of the piston 103 and the plunger 106 fitting into it are so shaped that in the initial position they together constitute a seal between compartments 109 and 110 but movement of the plunger to urge the intermediate piston towards the sealing piston causes relative movement therebetween and a channel is opened between the thinner end portion 161 of the plunger and the piston, the abutment ridge 115 (which is channeled to allow passage of liquid) urging the piston in the correct direction. When the two pistons meet and mixing is complete, the sealing piston (and hence the intermediate piston also) are urged down the ampoule by means such as a shaped ridge 197 on the plunger cooperating with a groove of appropriate profile in the sealing piston (Figs. 1 to 5). Alternatively, an additional plunger fitted outside the plunger for the intermediate piston and acting on both the sealing piston and the inner plunger (Figs. 8, 9, 10 and 12) may be used. Figs. 12 and 13 (not shown) depict a device in which a duct 12a passes axially through the plunger 6a from a point 19 initially closed by the piston 3a but which opens into the upper compartment when the plunger first moves, the ridge 20 serving to hold the plunger and piston together with the duct open during subsequent movement of the plunger.
GB5744/68A 1968-02-05 1968-02-05 Improvements in or relating to two chamber injection ampoules Expired GB1214053A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB5744/68A GB1214053A (en) 1968-02-05 1968-02-05 Improvements in or relating to two chamber injection ampoules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5744/68A GB1214053A (en) 1968-02-05 1968-02-05 Improvements in or relating to two chamber injection ampoules

Publications (1)

Publication Number Publication Date
GB1214053A true GB1214053A (en) 1970-12-02

Family

ID=9801839

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5744/68A Expired GB1214053A (en) 1968-02-05 1968-02-05 Improvements in or relating to two chamber injection ampoules

Country Status (1)

Country Link
GB (1) GB1214053A (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985122A (en) * 1975-06-04 1976-10-12 Medical Development Corporation Multi-piston syringe device
WO1982000457A1 (en) * 1980-07-31 1982-02-18 Res & Chem Corp Prod Improved barrier two part pairing and dispensing cartridge
EP0082251A1 (en) * 1981-12-22 1983-06-29 Contraves Ag Syringe for two fluids
US4874381A (en) * 1988-02-16 1989-10-17 Arzheimittel Gmbh Apotheker Vetter & Co. Ravensburg Hypodermic syringe
US4994043A (en) * 1987-06-16 1991-02-19 Akzo N.V. Two compartment syringe
EP0440846A1 (en) * 1990-02-07 1991-08-14 Arzneimittel GmbH Apotheker Vetter & Co. Ravensburg Two-compartment syringe and application process
EP0652019A1 (en) * 1993-11-08 1995-05-10 Ferring Arzneimittel GmbH Mixing and administration syringe
GB2338428A (en) * 1998-06-19 1999-12-22 David Grant A syringe with an agitator whose shaft passes through a slidable dispensing plunger
WO2007095036A3 (en) * 2006-02-10 2007-10-04 Dow Global Technologies Inc Retractable pin mixing sample forming device and method
WO2007116086A1 (en) * 2006-04-12 2007-10-18 Glaxosmithkline Biologicals S.A. Syringe with sequentially moving plunger flanges
CN102784426A (en) * 2011-05-16 2012-11-21 吴振文 Syringe with a needle
CN103029913A (en) * 2011-09-30 2013-04-10 汤维哲 Double-dye container
GB2514891A (en) * 2013-03-26 2014-12-10 Consort Medical Plc Improved syringe assembly
WO2015009868A1 (en) * 2013-07-16 2015-01-22 Unitract Syringe Pty Ltd Syringes for repetitive mixing and delivery of injectables

Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985122A (en) * 1975-06-04 1976-10-12 Medical Development Corporation Multi-piston syringe device
WO1982000457A1 (en) * 1980-07-31 1982-02-18 Res & Chem Corp Prod Improved barrier two part pairing and dispensing cartridge
US4371094A (en) * 1980-07-31 1983-02-01 Products Research & Chemical Corporation Barrier two part pairing and dispensing cartridge
EP0082251A1 (en) * 1981-12-22 1983-06-29 Contraves Ag Syringe for two fluids
US4465476A (en) * 1981-12-22 1984-08-14 Contraves Ag Injection syringe for injecting two liquids
US4994043A (en) * 1987-06-16 1991-02-19 Akzo N.V. Two compartment syringe
US4874381A (en) * 1988-02-16 1989-10-17 Arzheimittel Gmbh Apotheker Vetter & Co. Ravensburg Hypodermic syringe
EP0440846A1 (en) * 1990-02-07 1991-08-14 Arzneimittel GmbH Apotheker Vetter & Co. Ravensburg Two-compartment syringe and application process
EP0652019A1 (en) * 1993-11-08 1995-05-10 Ferring Arzneimittel GmbH Mixing and administration syringe
US5630800A (en) * 1993-11-08 1997-05-20 Ferring Arzneimettel Gmbh Injection syringe for the missing and application of injection substances
GB2338428A (en) * 1998-06-19 1999-12-22 David Grant A syringe with an agitator whose shaft passes through a slidable dispensing plunger
WO2007095036A3 (en) * 2006-02-10 2007-10-04 Dow Global Technologies Inc Retractable pin mixing sample forming device and method
US8220985B2 (en) 2006-02-10 2012-07-17 Dow Global Technologies Llc Retractable pin mixing sample forming device
WO2007116086A1 (en) * 2006-04-12 2007-10-18 Glaxosmithkline Biologicals S.A. Syringe with sequentially moving plunger flanges
CN102784426A (en) * 2011-05-16 2012-11-21 吴振文 Syringe with a needle
CN103029913A (en) * 2011-09-30 2013-04-10 汤维哲 Double-dye container
GB2514891A (en) * 2013-03-26 2014-12-10 Consort Medical Plc Improved syringe assembly
GB2514891B (en) * 2013-03-26 2015-06-24 Consort Medical Plc Improved syringe assembly
US11185637B2 (en) 2013-03-26 2021-11-30 Consort Medical Plc Mixing syringe assembly
US9597454B2 (en) 2013-07-16 2017-03-21 Unitract Syringe Pty Ltd. Syringes for prefilled and fill-at-use mixing and drug delivery
EP3431124A3 (en) * 2013-07-16 2019-03-27 UNL Holdings LLC Syringes for sequential delivery of injectables
CN105530976A (en) * 2013-07-16 2016-04-27 尤尼特拉克特注射器公司 Syringes for Sequential Delivery of Injectables
CN105592875A (en) * 2013-07-16 2016-05-18 尤尼特拉克特注射器公司 Syringes for prefilled and fill-at-use mixing and drug delivery
US9586008B2 (en) 2013-07-16 2017-03-07 Unitract Syringe Pty Ltd Syringes for sequential delivery of injectables
US9592343B2 (en) 2013-07-16 2017-03-14 Unitract Syringe Pty Ltd. Syringes for repetitive mixing and delivery of injectables
WO2015009868A1 (en) * 2013-07-16 2015-01-22 Unitract Syringe Pty Ltd Syringes for repetitive mixing and delivery of injectables
WO2015009866A3 (en) * 2013-07-16 2015-04-30 Unitract Syringe Pty Ltd Syringes for sequential delivery of injectables
AU2014290081B2 (en) * 2013-07-16 2019-05-16 Unl Holdings Llc Syringes for repetitive mixing and delivery of injectables
CN105592875B (en) * 2013-07-16 2019-06-07 尤尼特拉克特注射器公司 The syringe of mixing and drug conveying when for pre-filled and use
AU2014290079B2 (en) * 2013-07-16 2019-08-08 Unl Holdings Llc Syringes for sequential delivery of injectables
JP2019162534A (en) * 2013-07-16 2019-09-26 ユーエヌエル ホールディングス リミテッド ライアビリティ カンパニー Syringe for sequentially delivering injectable
CN110917450A (en) * 2013-07-16 2020-03-27 尤尼特拉克特注射器公司 Injector for sequential delivery of injectables
US10898651B2 (en) 2013-07-16 2021-01-26 Unl Holdings Llc Syringes for prefilled and fill-at-use mixing and drug delivery
WO2015009871A1 (en) * 2013-07-16 2015-01-22 Unitract Syringe Pty Ltd Syringes for prefilled and fill-at-use mixing and drug delivery

Similar Documents

Publication Publication Date Title
GB1214053A (en) Improvements in or relating to two chamber injection ampoules
GB1484600A (en) Two-chamber mixing syringe
GB1193846A (en) Hypodermic Injection Syringe
HK38183A (en) Syringe
DE69622909D1 (en) Pre-filled syringe for injecting two liquids
ES445178A1 (en) Medicament infusor unit
DK162480C (en) hypodermic syringe
DK0821599T3 (en) Syringe cylinder for freeze drying, reconstitution and administration
NZ318732A (en) Tamper evident syringe design
GB1089608A (en) Container
DE69004949D1 (en) ELONGATED CONTAINER WITH TWO SEPARATE CHAMBERS ON THE SAME LONG AXIS.
ES288232A1 (en) Syringe
GB1212753A (en) Hypodermic syringe
GB781554A (en) Improvements in or relating to cylindrical ampoules for surgical injection
IE43036L (en) Piston member for an injection syringe
GB743789A (en) Improvements in or relating to cartridges and the like tubular containers for use in dispensing liquids
GB1336579A (en) Valves
ES445769A1 (en) Vial-syringe
GB1316323A (en) Mixing vial
GB1168201A (en) Improvements in and relating to Injection Syringes
DE3171579D1 (en) Injection syringe
GB1402428A (en) Injection syringes
GB1306126A (en)
GB1162249A (en) Improvements in or relating to Stoppers for Freeze Drying Containers
GB1087360A (en) Disposable hypodermic syringe

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee