GB1292715A - 03-polycarbonalkyl-18-norpregnenes - Google Patents
03-polycarbonalkyl-18-norpregnenesInfo
- Publication number
- GB1292715A GB1292715A GB536870A GB536870A GB1292715A GB 1292715 A GB1292715 A GB 1292715A GB 536870 A GB536870 A GB 536870A GB 536870 A GB536870 A GB 536870A GB 1292715 A GB1292715 A GB 1292715A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- formula
- alkanoylation
- glyoxalate
- dehydrogenation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003431 steroids Chemical class 0.000 abstract 3
- HZNVUJQVZSTENZ-UHFFFAOYSA-N 2,3-dichloro-5,6-dicyano-1,4-benzoquinone Chemical compound ClC1=C(Cl)C(=O)C(C#N)=C(C#N)C1=O HZNVUJQVZSTENZ-UHFFFAOYSA-N 0.000 abstract 2
- 230000010933 acylation Effects 0.000 abstract 2
- 238000005917 acylation reaction Methods 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 2
- HHLFWLYXYJOTON-UHFFFAOYSA-N glyoxylic acid Chemical group OC(=O)C=O HHLFWLYXYJOTON-UHFFFAOYSA-N 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- -1 C2U Steroids Chemical class 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003862 glucocorticoid Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000012336 iodinating agent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79914869A | 1969-02-05 | 1969-02-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1292715A true GB1292715A (en) | 1972-10-11 |
Family
ID=25175147
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB536870A Expired GB1292715A (en) | 1969-02-05 | 1970-02-04 | 03-polycarbonalkyl-18-norpregnenes |
| GB5043371A Expired GB1292716A (en) | 1969-02-05 | 1970-02-04 | 03-polycarbonalkyl-18-norpregnenes |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5043371A Expired GB1292716A (en) | 1969-02-05 | 1970-02-04 | 03-polycarbonalkyl-18-norpregnenes |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE745563A (de) |
| DE (1) | DE2004353A1 (de) |
| FR (1) | FR2034520B1 (de) |
| GB (2) | GB1292715A (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010522732A (ja) * | 2007-03-29 | 2010-07-08 | ナームローゼ・フエンノートチヤツプ・オルガノン | 鉱質コルチコイド受容体アンタゴニスト |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1453219A (fr) * | 1963-07-26 | 1966-06-03 | Roussel Uclaf | Dérivés stéroïdes et procédé de préparation |
-
1970
- 1970-01-30 DE DE19702004353 patent/DE2004353A1/de active Pending
- 1970-02-04 FR FR7003963A patent/FR2034520B1/fr not_active Expired
- 1970-02-04 GB GB536870A patent/GB1292715A/en not_active Expired
- 1970-02-04 GB GB5043371A patent/GB1292716A/en not_active Expired
- 1970-02-05 BE BE745563D patent/BE745563A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2034520A1 (de) | 1970-12-11 |
| FR2034520B1 (de) | 1974-02-01 |
| DE2004353A1 (de) | 1970-09-24 |
| BE745563A (fr) | 1970-08-05 |
| GB1292716A (en) | 1972-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |