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GB1280288A - Pyrimidopyrimidines - Google Patents

Pyrimidopyrimidines

Info

Publication number
GB1280288A
GB1280288A GB20659/71A GB2065971A GB1280288A GB 1280288 A GB1280288 A GB 1280288A GB 20659/71 A GB20659/71 A GB 20659/71A GB 2065971 A GB2065971 A GB 2065971A GB 1280288 A GB1280288 A GB 1280288A
Authority
GB
United Kingdom
Prior art keywords
morpholino
atom
group
formula
interchanged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20659/71A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of GB1280288A publication Critical patent/GB1280288A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1280288 Pyrimidopyrimidines DR KARL THOMAE GmbH 19 April 1971 [30 Jan 1970] 20659/71 Heading C2C Compounds of the general formula (R 1 = C 1-4 alkyl, C 2-6 hydroxyalkyl, C 3-4 methoxyalkyl; R 2 = C 4-6 hydroxyalkyl) are prepared by (a) reducing a compound of the formula and oxidizing the product, or (b) reacting a compound of the formula (A = atom or group which may be interchanged with NR 1 R 2 by reaction with an appropriate amine and A 1 , A 2 = morpholino, or A = NR 1 R 2 and at least one of A 1 , A 2 = atom or group which may be interchanged with morpholino by reaction with morpholine, the remaining A 1 or A 2 representing morpholino when only one of A 1 , A 2 represents the interchangeable atom or group) with R 1 R 2 NH or morpholine. The above compounds possess heart and circulation activity and inhibit the aggregation of thrombocytes. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
GB20659/71A 1970-01-30 1971-04-19 Pyrimidopyrimidines Expired GB1280288A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702004202 DE2004202A1 (en) 1970-01-30 1970-01-30 New 2,6-dimorpholino-8-alkanolamino-pyrimido [5,4-d] pyrimidines

Publications (1)

Publication Number Publication Date
GB1280288A true GB1280288A (en) 1972-07-05

Family

ID=5760962

Family Applications (1)

Application Number Title Priority Date Filing Date
GB20659/71A Expired GB1280288A (en) 1970-01-30 1971-04-19 Pyrimidopyrimidines

Country Status (16)

Country Link
AT (2) AT302343B (en)
AU (1) AU2476671A (en)
BE (1) BE762328A (en)
BG (1) BG18611A3 (en)
DE (1) DE2004202A1 (en)
DK (1) DK126653B (en)
ES (2) ES387123A1 (en)
FR (1) FR2081472A1 (en)
GB (1) GB1280288A (en)
HU (1) HU163361B (en)
IE (1) IE34922B1 (en)
IL (1) IL36096A0 (en)
NL (1) NL7101117A (en)
RO (2) RO57988A7 (en)
SU (1) SU423298A3 (en)
ZA (1) ZA71578B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8272225B2 (en) 2008-09-09 2012-09-25 Leica Biosystems Nussloch Gmbh Apparatus for cooling cassette magazines containing tissue samples

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1051445B (en) 1975-07-16 1981-04-21 Recordati Chem Pharm THERAPEUTICALLY ACTIVE BENZOIC ACID DERIVATIVES AND PROCEDURE TO PREPARE THEM

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8272225B2 (en) 2008-09-09 2012-09-25 Leica Biosystems Nussloch Gmbh Apparatus for cooling cassette magazines containing tissue samples

Also Published As

Publication number Publication date
AT302343B (en) 1972-10-10
IE34922B1 (en) 1975-09-17
BG18611A3 (en) 1975-02-25
IE34922L (en) 1971-07-30
ES387123A1 (en) 1973-05-16
SU423298A3 (en) 1974-04-05
ZA71578B (en) 1971-11-24
DE2004202A1 (en) 1971-08-05
ES393417A1 (en) 1974-09-16
NL7101117A (en) 1971-08-03
BE762328A (en) 1971-07-29
FR2081472A1 (en) 1971-12-03
AT301562B (en) 1972-09-11
AU2476671A (en) 1972-08-03
RO57988A7 (en) 1975-06-15
DK126653B (en) 1973-08-06
SU383298A3 (en) 1973-05-25
IL36096A0 (en) 1971-03-24
RO57780A7 (en) 1975-03-15
HU163361B (en) 1973-07-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees