GB1260939A - beta-HYDRAZINO-ALKANOIC ACIDS AND PROCESSES FOR THEIR PREPARATION - Google Patents
beta-HYDRAZINO-ALKANOIC ACIDS AND PROCESSES FOR THEIR PREPARATIONInfo
- Publication number
- GB1260939A GB1260939A GB20164/69A GB2016469A GB1260939A GB 1260939 A GB1260939 A GB 1260939A GB 20164/69 A GB20164/69 A GB 20164/69A GB 2016469 A GB2016469 A GB 2016469A GB 1260939 A GB1260939 A GB 1260939A
- Authority
- GB
- United Kingdom
- Prior art keywords
- chr
- hydrazino
- alkanoic acids
- beta
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000007513 acids Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000000935 antidepressant agent Substances 0.000 abstract 2
- 229940005513 antidepressants Drugs 0.000 abstract 2
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,260,939. Antidepressants. ASSIA CHEMICAL LABORATORIES Ltd. 21 April, 1969 [6 May, 1968], No. 20164/69. Heading A5B. [Also in Division C2] Pharmaceutical compositions, suitable for oral, parenteral or topical administration, contain beta-hydrazino-alkanoic acids of the formulae: H 2 N.NR 3 .CHR 2 .CHR 1 .COOH or R 3 NH.NH.CHR 2 .CHR 1 .COOH wherein R 1 and R 2 , the same or different, are H, phenyl or C 1-5 alkyl; and R 3 is H, C 1-6 alkyl, cycloalkyl, phenyl, benzyl or phenethyl; or esters, acid halides, amides or salts thereof and pharmaceutically acceptable carriers or diluents therefor. The said compounds are monoamine inhibitors and have antidepressant activity.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL29945A IL29945A (en) | 1968-05-06 | 1968-05-06 | Beta-hydrazino carboxylic acids and processes for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1260939A true GB1260939A (en) | 1972-01-19 |
Family
ID=11044452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB20164/69A Expired GB1260939A (en) | 1968-05-06 | 1969-04-21 | beta-HYDRAZINO-ALKANOIC ACIDS AND PROCESSES FOR THEIR PREPARATION |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB1260939A (en) |
| IL (1) | IL29945A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5300514A (en) * | 1990-07-17 | 1994-04-05 | Eli Lilly And Company | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof |
| US5399565A (en) * | 1990-07-17 | 1995-03-21 | Eli Lilly And Company | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations therof |
| WO2017134547A1 (en) | 2016-02-01 | 2017-08-10 | Pfizer Inc. | Tubulysin analogs and methods for their preparation |
-
1968
- 1968-05-06 IL IL29945A patent/IL29945A/en unknown
-
1969
- 1969-04-21 GB GB20164/69A patent/GB1260939A/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5300514A (en) * | 1990-07-17 | 1994-04-05 | Eli Lilly And Company | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof |
| US5399565A (en) * | 1990-07-17 | 1995-03-21 | Eli Lilly And Company | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations therof |
| US5643926A (en) * | 1990-07-17 | 1997-07-01 | Eli Lilly And Company | Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations thereof |
| WO2017134547A1 (en) | 2016-02-01 | 2017-08-10 | Pfizer Inc. | Tubulysin analogs and methods for their preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| IL29945A0 (en) | 1968-07-25 |
| IL29945A (en) | 1973-08-29 |
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