GB1240545A - Silver-containing therapeutic agents - Google Patents
Silver-containing therapeutic agentsInfo
- Publication number
- GB1240545A GB1240545A GB33831/68A GB3383168A GB1240545A GB 1240545 A GB1240545 A GB 1240545A GB 33831/68 A GB33831/68 A GB 33831/68A GB 3383168 A GB3383168 A GB 3383168A GB 1240545 A GB1240545 A GB 1240545A
- Authority
- GB
- United Kingdom
- Prior art keywords
- silver
- july
- carrier
- sulphadiazine
- therapeutic agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052709 silver Inorganic materials 0.000 title abstract 11
- 239000004332 silver Substances 0.000 title abstract 11
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 title abstract 10
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 239000002674 ointment Substances 0.000 abstract 2
- UEJSSZHHYBHCEL-UHFFFAOYSA-N silver(1+) sulfadiazinate Chemical compound [Ag+].C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1 UEJSSZHHYBHCEL-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 239000004098 Tetracycline Substances 0.000 abstract 1
- RRDRHWJDBOGQHN-JWCTVYNTSA-N [2-[(2s,5r,8s,11s,14r,17s,22s)-17-[(1r)-1-hydroxyethyl]-22-[[(2s)-2-[[(2s,3r)-3-hydroxy-2-[[(2s)-2-[6-methyloctanoyl(sulfomethyl)amino]-4-(sulfomethylamino)butanoyl]amino]butyl]amino]-4-(sulfomethylamino)butanoyl]amino]-5,8-bis(2-methylpropyl)-3,6,9,12,15 Chemical compound CCC(C)CCCCC(=O)N(CS(O)(=O)=O)[C@@H](CCNCS(O)(=O)=O)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCNCS(O)(=O)=O)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](CCNCS(O)(=O)=O)NC(=O)[C@H](CCNCS(O)(=O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCNCS(O)(=O)=O)NC1=O RRDRHWJDBOGQHN-JWCTVYNTSA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- XIURVHNZVLADCM-IUODEOHRSA-N cefalotin Chemical compound N([C@H]1[C@@H]2N(C1=O)C(=C(CS2)COC(=O)C)C(O)=O)C(=O)CC1=CC=CS1 XIURVHNZVLADCM-IUODEOHRSA-N 0.000 abstract 1
- 229960000603 cefalotin Drugs 0.000 abstract 1
- 229940108538 colistimethate Drugs 0.000 abstract 1
- 108700028201 colistinmethanesulfonic acid Proteins 0.000 abstract 1
- 239000008311 hydrophilic ointment Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- NBYLLBXLDOPANK-UHFFFAOYSA-M silver 2-carboxyphenolate hydrate Chemical compound C1=CC=C(C(=C1)C(=O)O)[O-].O.[Ag+] NBYLLBXLDOPANK-UHFFFAOYSA-M 0.000 abstract 1
- -1 silver tetracycline Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 abstract 1
- QPPBRPIAZZHUNT-UHFFFAOYSA-N sulfamerazine Chemical compound CC1=CC=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 QPPBRPIAZZHUNT-UHFFFAOYSA-N 0.000 abstract 1
- 229960002597 sulfamerazine Drugs 0.000 abstract 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 abstract 1
- 229960002211 sulfapyridine Drugs 0.000 abstract 1
- GECHUMIMRBOMGK-UHFFFAOYSA-N sulfapyridine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=CC=CC=N1 GECHUMIMRBOMGK-UHFFFAOYSA-N 0.000 abstract 1
- JNMRHUJNCSQMMB-UHFFFAOYSA-N sulfathiazole Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=NC=CS1 JNMRHUJNCSQMMB-UHFFFAOYSA-N 0.000 abstract 1
- 229960001544 sulfathiazole Drugs 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 229960002180 tetracycline Drugs 0.000 abstract 1
- 229930101283 tetracycline Natural products 0.000 abstract 1
- 235000019364 tetracycline Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1,240,545. Ointments containing silver sulphadiazine. RESEARCH CORP. 16 July, 1968 [17 July, 1967], No. 33831/68. Heading A5B. An ointment for the treatment of burns comprises silver sulphadiazine and a carrier. The carrier may be an oil-in-water emulsion or a hydrophilic ointment base. Optional ingredients are (a) silver salicylate, (b) a silver salt of an antibiotic e.g. silver penicillin, silver cephalothin, silver colistimethate or silver tetracycline, (c) another silver sulphonamide such as silver sulphamerazine, silver sulphonanilide, silver sulphamylon, silver sulphathiazole or silver sulphapyridine, (d) an aqueous solution of chloride ions e.g. NaCl. Specification 1,240,546 is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65383067A | 1967-07-17 | 1967-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1240545A true GB1240545A (en) | 1971-07-28 |
Family
ID=24622450
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4945970A Expired GB1240546A (en) | 1967-07-17 | 1968-07-16 | Improvements in or relating to antibacterial compounds |
| GB33831/68A Expired GB1240545A (en) | 1967-07-17 | 1968-07-16 | Silver-containing therapeutic agents |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4945970A Expired GB1240546A (en) | 1967-07-17 | 1968-07-16 | Improvements in or relating to antibacterial compounds |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE718183A (en) |
| DE (1) | DE1792053B1 (en) |
| ES (1) | ES356142A1 (en) |
| FR (2) | FR1586125A (en) |
| GB (2) | GB1240546A (en) |
| IE (1) | IE32197B1 (en) |
| NL (1) | NL6809794A (en) |
| PH (1) | PH10639A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992004029A1 (en) * | 1990-08-29 | 1992-03-19 | Donald Leslie Simmons | Composition containing silver sulfadiazine and benzocaine for use in the treatment of wounds following laser surgery |
| EP0480189A1 (en) * | 1990-10-05 | 1992-04-15 | Altergon S.A. | Pharmaceutical compositions for topical use comprising hyaluronic acid sodium salt and disinfectant substances |
| EP0291159A3 (en) * | 1987-04-01 | 1993-03-17 | Dak-Laboratoriet A/S | Aminosalicylic-acid derivatives for the treatment of psoriasis |
| WO2004103980A1 (en) * | 2003-05-21 | 2004-12-02 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type i |
| WO2004112784A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use i |
| WO2004112783A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use iv |
| WO2004112779A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use vii |
| WO2004112782A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use v |
| WO2004113310A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | Use of an inhibitor of 11-b-hydroxysteroid dehydrogenase type 1 compounds for promoting wound healing |
| WO2004112785A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use iii |
| US7074788B2 (en) | 2001-11-22 | 2006-07-11 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| US7173030B2 (en) | 2003-05-21 | 2007-02-06 | Biovitrum Ab | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4049802A (en) | 1975-03-19 | 1977-09-20 | Research Corporation | Zinc sulfadiazine and its use in the treatment of burns |
| DE2804931A1 (en) * | 1978-02-06 | 1979-08-16 | Fresenius Chem Pharm Ind | METAL SULFADIAZINE IN FINE PARTICULAR FORM |
| US4384117A (en) * | 1980-03-18 | 1983-05-17 | The United States Of America As Represented By The Secretary Of The Army | Silver metachloridine |
| BRPI1104620B1 (en) * | 2011-09-09 | 2020-04-07 | Lucia Teixeira De Carvalho | pharmaceutical composition for the treatment of burns and skin lesions and their preparation process |
-
1968
- 1968-07-05 PH PH9358A patent/PH10639A/en unknown
- 1968-07-10 NL NL6809794A patent/NL6809794A/xx unknown
- 1968-07-13 ES ES356142A patent/ES356142A1/en not_active Expired
- 1968-07-15 IE IE83968A patent/IE32197B1/en unknown
- 1968-07-16 FR FR1586125D patent/FR1586125A/fr not_active Expired
- 1968-07-16 GB GB4945970A patent/GB1240546A/en not_active Expired
- 1968-07-16 GB GB33831/68A patent/GB1240545A/en not_active Expired
- 1968-07-17 DE DE19681792053 patent/DE1792053B1/en active Pending
- 1968-07-17 BE BE718183D patent/BE718183A/xx not_active IP Right Cessation
- 1968-10-11 FR FR169591A patent/FR8146M/fr not_active Expired
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0291159A3 (en) * | 1987-04-01 | 1993-03-17 | Dak-Laboratoriet A/S | Aminosalicylic-acid derivatives for the treatment of psoriasis |
| WO1992004029A1 (en) * | 1990-08-29 | 1992-03-19 | Donald Leslie Simmons | Composition containing silver sulfadiazine and benzocaine for use in the treatment of wounds following laser surgery |
| EP0480189A1 (en) * | 1990-10-05 | 1992-04-15 | Altergon S.A. | Pharmaceutical compositions for topical use comprising hyaluronic acid sodium salt and disinfectant substances |
| US7074788B2 (en) | 2001-11-22 | 2006-07-11 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| WO2004103980A1 (en) * | 2003-05-21 | 2004-12-02 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type i |
| US7173030B2 (en) | 2003-05-21 | 2007-02-06 | Biovitrum Ab | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
| WO2004112784A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use i |
| WO2004112783A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use iv |
| WO2004112779A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use vii |
| WO2004112782A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use v |
| WO2004113310A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | Use of an inhibitor of 11-b-hydroxysteroid dehydrogenase type 1 compounds for promoting wound healing |
| WO2004112785A1 (en) * | 2003-06-25 | 2004-12-29 | Biovitrum Ab | New use iii |
Also Published As
| Publication number | Publication date |
|---|---|
| ES356142A1 (en) | 1970-02-16 |
| NL6809794A (en) | 1969-01-21 |
| IE32197L (en) | 1969-01-17 |
| BE718183A (en) | 1969-01-17 |
| FR8146M (en) | 1970-08-17 |
| PH10639A (en) | 1977-07-22 |
| FR1586125A (en) | 1970-02-13 |
| IE32197B1 (en) | 1973-05-16 |
| DE1792053B1 (en) | 1971-07-29 |
| GB1240546A (en) | 1971-07-28 |
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