GB1135898A - - Google Patents
Info
- Publication number
- GB1135898A GB1135898A GB1135898DA GB1135898A GB 1135898 A GB1135898 A GB 1135898A GB 1135898D A GB1135898D A GB 1135898DA GB 1135898 A GB1135898 A GB 1135898A
- Authority
- GB
- United Kingdom
- Prior art keywords
- quinazoline
- diamino
- mixture
- malonate
- aldehyde
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 6
- 239000000203 mixture Substances 0.000 abstract 3
- DGBLFFZFXKTSMW-UHFFFAOYSA-N 2,4-diaminoquinazoline-6-carbaldehyde Chemical compound C1=C(C=O)C=CC2=NC(N)=NC(N)=C21 DGBLFFZFXKTSMW-UHFFFAOYSA-N 0.000 abstract 2
- 239000007868 Raney catalyst Substances 0.000 abstract 2
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 2
- 229910000564 Raney nickel Inorganic materials 0.000 abstract 2
- -1 alkyl di-esters Chemical class 0.000 abstract 2
- 150000003246 quinazolines Chemical class 0.000 abstract 2
- FGNJZOQLZLEBME-UHFFFAOYSA-N 2,4-diaminoquinazoline-6-carbonitrile Chemical compound C1=C(C#N)C=CC2=NC(N)=NC(N)=C21 FGNJZOQLZLEBME-UHFFFAOYSA-N 0.000 abstract 1
- FJNLCHNQVJVCPY-UHFFFAOYSA-N 2-n-methoxy-2-n-methyl-4-n,6-n-dipropyl-1,3,5-triazine-2,4,6-triamine Chemical compound CCCNC1=NC(NCCC)=NC(N(C)OC)=N1 FJNLCHNQVJVCPY-UHFFFAOYSA-N 0.000 abstract 1
- BXRFQSNOROATLV-UHFFFAOYSA-N 4-nitrobenzaldehyde Chemical compound [O-][N+](=O)C1=CC=C(C=O)C=C1 BXRFQSNOROATLV-UHFFFAOYSA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- UXHPVJSYSNYBCI-UHFFFAOYSA-N diethyl 2-[(4-aminobenzoyl)amino]propanedioate Chemical compound C(C)OC(C(C(=O)OCC)NC(C1=CC=C(C=C1)N)=O)=O UXHPVJSYSNYBCI-UHFFFAOYSA-N 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- HKOOXMFOFWEVGF-UHFFFAOYSA-N phenylhydrazine Chemical compound NNC1=CC=CC=C1 HKOOXMFOFWEVGF-UHFFFAOYSA-N 0.000 abstract 1
- 229940067157 phenylhydrazine Drugs 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1135898A true GB1135898A (es) |
Family
ID=1759448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1135898D Active GB1135898A (es) |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1135898A (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050064A3 (en) * | 1999-02-26 | 2001-04-05 | Inst Of Molecul & Cell Biology | Synergistic combination for treatment of viral-mediated diseases |
-
0
- GB GB1135898D patent/GB1135898A/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050064A3 (en) * | 1999-02-26 | 2001-04-05 | Inst Of Molecul & Cell Biology | Synergistic combination for treatment of viral-mediated diseases |
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