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GB1118799A - Substituted benzyl alcohols - Google Patents

Substituted benzyl alcohols

Info

Publication number
GB1118799A
GB1118799A GB5075767A GB5075767A GB1118799A GB 1118799 A GB1118799 A GB 1118799A GB 5075767 A GB5075767 A GB 5075767A GB 5075767 A GB5075767 A GB 5075767A GB 1118799 A GB1118799 A GB 1118799A
Authority
GB
United Kingdom
Prior art keywords
alkyl
alkoxy
hydrogen
alkanoyl
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5075767A
Inventor
Robert Long Clark
Edward Franklin Rogers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority claimed from GB54018/65A external-priority patent/GB1118798A/en
Publication of GB1118799A publication Critical patent/GB1118799A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Novel compounds having the formula <FORM:1118799/C2/1> in which R is a C1- 5 alkyl radical, A is -NO2 or NR4R5, where R4 is hydrogen, C1- 5 alkyl, C2- 6 alkanoyl or benzoyl and R5 is hydrogen or C1- 5 alkyl, and R3 is hydrogen or C2- 6 alkanoyl, and their non-toxic acid addition salts are obtained by reacting a 2-(C1- 5 alkoxy)-4-nitro-benzoi acid with a borohydride reducing agent in the presence of an aluminium halide to produc a 2-(C1- 5 alkoxy)-4-nitrobenzyl alcohol and if desired reacting the latter in the presence of a hydrogenation catalyst to produce a 2-(C1- 5 alkoxy)-4-aminobenzyl alcohol. The O-acyl and N-acyl derivatives of the 4-nitro- and 4-aminobenzyl alcohols are obtained by reaction with an appropriate acylating agent while the N-alkyl derivatives are obtained by alkylation.
GB5075767A 1964-12-31 1965-12-21 Substituted benzyl alcohols Expired GB1118799A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42253664A 1964-12-31 1964-12-31
GB54018/65A GB1118798A (en) 1964-12-31 1965-12-21 Substituted benzylamines

Publications (1)

Publication Number Publication Date
GB1118799A true GB1118799A (en) 1968-07-03

Family

ID=26267391

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5075767A Expired GB1118799A (en) 1964-12-31 1965-12-21 Substituted benzyl alcohols

Country Status (1)

Country Link
GB (1) GB1118799A (en)

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