GB1193438A - Barbituric Acid Derivatives, preparation thereof and Pharmaceutical Compositions containing them - Google Patents
Barbituric Acid Derivatives, preparation thereof and Pharmaceutical Compositions containing themInfo
- Publication number
- GB1193438A GB1193438A GB4812066A GB4812066A GB1193438A GB 1193438 A GB1193438 A GB 1193438A GB 4812066 A GB4812066 A GB 4812066A GB 4812066 A GB4812066 A GB 4812066A GB 1193438 A GB1193438 A GB 1193438A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pharmaceutical compositions
- barbituric acid
- preparation
- compositions containing
- acid derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000007656 barbituric acids Chemical class 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- DNZPLHRZXUJATK-UHFFFAOYSA-N 2-sulfanylidene-5-[[5-[2-(trifluoromethyl)phenyl]furan-2-yl]methyl]-1,3-diazinane-4,6-dione Chemical compound FC(F)(F)C1=CC=CC=C1C(O1)=CC=C1CC1C(=O)NC(=S)NC1=O DNZPLHRZXUJATK-UHFFFAOYSA-N 0.000 abstract 1
- 230000001410 anti-tremor Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229940125717 barbiturate Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,193,438. Medicines comprising barbiturates. P. GOLD-AUBERT AND D. MELKONIAN. 26 Oct., 1967 [26 Oct., 1966], No. 48120/66. Heading A5B. [Also in Division C2] Pharmaceutical compositions, having antitremor activity, tranquillising and sedative properties, contain as the active ingredient at least one novel barbituric acid derivative of the formula wherein R<SP>1</SP> and R<SP>2</SP>, which may be the same or different, are hydrogen atoms, or aliphatic araliphatic or aryl groups, and R<SP>3</SP> and R<SP>4</SP>, which may be the same or different, are aliphatic groups each of which carries at least one carbamyloxy group. The above compositions may also contain as further active ingredients at least one compound of the general formula, above in which R<SP>4</SP> is hydrogen and/or at least one compound of a general formula above in which both R<SP>3</SP> and R<SP>4</SP> are hydrogen.
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4812066A GB1193438A (en) | 1966-10-26 | 1966-10-26 | Barbituric Acid Derivatives, preparation thereof and Pharmaceutical Compositions containing them |
| FR1549453D FR1549453A (en) | 1966-10-26 | 1967-10-20 | |
| CH1483167A CH514595A (en) | 1966-10-26 | 1967-10-24 | Mixts of barbiturate derivs as tranquillisers sedatives |
| ES346424A ES346424A1 (en) | 1966-10-26 | 1967-10-25 | Barbituric Acid Derivatives, preparation thereof and Pharmaceutical Compositions containing them |
| BE705672D BE705672A (en) | 1966-10-26 | 1967-10-26 | |
| NL6714587A NL6714587A (en) | 1966-10-26 | 1967-10-26 | |
| DE19671695043 DE1695043C2 (en) | 1966-10-26 | 1967-10-26 | Pharmaceutical compositions having sedative and tranquilizing properties |
| AT973067A AT299238B (en) | 1966-10-26 | 1967-10-27 | Process for the production of new barbituric acid derivatives |
| FR137521A FR8022M (en) | 1966-10-26 | 1968-01-26 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4812066A GB1193438A (en) | 1966-10-26 | 1966-10-26 | Barbituric Acid Derivatives, preparation thereof and Pharmaceutical Compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1193438A true GB1193438A (en) | 1970-06-03 |
Family
ID=10447466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4812066A Expired GB1193438A (en) | 1966-10-26 | 1966-10-26 | Barbituric Acid Derivatives, preparation thereof and Pharmaceutical Compositions containing them |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT299238B (en) |
| BE (1) | BE705672A (en) |
| CH (1) | CH514595A (en) |
| DE (1) | DE1695043C2 (en) |
| ES (1) | ES346424A1 (en) |
| FR (2) | FR1549453A (en) |
| GB (1) | GB1193438A (en) |
| NL (1) | NL6714587A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2748794A1 (en) * | 1976-11-01 | 1978-05-03 | Sapos Sa | MALONYL URINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| FR2544312A1 (en) * | 1983-04-12 | 1984-10-19 | Sapos Sa | PROCESS FOR THE PREPARATION OF PYRIMIDINETRIONE DERIVATIVES AND THE THERAPEUTIC APPLICATION OF FEBARBAMATE THUS OBTAINED |
-
1966
- 1966-10-26 GB GB4812066A patent/GB1193438A/en not_active Expired
-
1967
- 1967-10-20 FR FR1549453D patent/FR1549453A/fr not_active Expired
- 1967-10-24 CH CH1483167A patent/CH514595A/en not_active IP Right Cessation
- 1967-10-25 ES ES346424A patent/ES346424A1/en not_active Expired
- 1967-10-26 DE DE19671695043 patent/DE1695043C2/en not_active Expired
- 1967-10-26 NL NL6714587A patent/NL6714587A/xx unknown
- 1967-10-26 BE BE705672D patent/BE705672A/xx not_active IP Right Cessation
- 1967-10-27 AT AT973067A patent/AT299238B/en not_active IP Right Cessation
-
1968
- 1968-01-26 FR FR137521A patent/FR8022M/fr not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2748794A1 (en) * | 1976-11-01 | 1978-05-03 | Sapos Sa | MALONYL URINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| US4185104A (en) * | 1976-11-01 | 1980-01-22 | Sapos S.A. | Tranquillizing complexes |
| FR2544312A1 (en) * | 1983-04-12 | 1984-10-19 | Sapos Sa | PROCESS FOR THE PREPARATION OF PYRIMIDINETRIONE DERIVATIVES AND THE THERAPEUTIC APPLICATION OF FEBARBAMATE THUS OBTAINED |
| EP0125046A1 (en) * | 1983-04-12 | 1984-11-14 | Sapos S.A. | Process for preparing pyrimidinetrione derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| AT299238B (en) | 1972-06-12 |
| FR8022M (en) | 1970-08-03 |
| CH514595A (en) | 1971-10-31 |
| ES346424A1 (en) | 1969-04-16 |
| DE1695043A1 (en) | 1972-04-27 |
| FR1549453A (en) | 1968-12-13 |
| BE705672A (en) | 1968-04-26 |
| NL6714587A (en) | 1968-04-29 |
| DE1695043C2 (en) | 1983-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 435 | Patent endorsed 'licences of right' on the date specified (sect. 35/1949) | ||
| PE20 | Patent expired after termination of 20 years |