GB1191443A - Quinoline Derivatives - Google Patents
Quinoline DerivativesInfo
- Publication number
- GB1191443A GB1191443A GB536969A GB536969A GB1191443A GB 1191443 A GB1191443 A GB 1191443A GB 536969 A GB536969 A GB 536969A GB 536969 A GB536969 A GB 536969A GB 1191443 A GB1191443 A GB 1191443A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- compositions
- aralkyl
- cooh
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 241000700605 Viruses Species 0.000 abstract 2
- 230000000840 anti-viral effect Effects 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229930182555 Penicillin Natural products 0.000 abstract 1
- 241000588769 Proteus <enterobacteria> Species 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000004098 Tetracycline Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 235000019364 tetracycline Nutrition 0.000 abstract 1
- 150000003522 tetracyclines Chemical class 0.000 abstract 1
- 229940040944 tetracyclines Drugs 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,191,443. Antiviral compositions. WARNER-LAMBERT PHARMACEUTICAL CO. 31 Jan., 1969 [23 Feb., 1968], No. 5369/69. Heading A5B. '[Also in Division C2] Pharmaceutical compositions, having antiviral activity, typically against certain respiratory viruses, foot and mouth viruses and gram negative bacilli, notably the Proteus group, contain as the active ingredients at least one compound of the formula wherein R 1 is H, C 1-7 alkyl, aryl, aralkyl, dialkylamino. alkyl or substituted C 1-7 alkyl; R 2 is COOR 1 , COOH, H. CON(R 1 ) 2 or CONHR 1 ; R 3 is 5, 6-, 6, 7-, or 7, 8- fused furon heterocyclic ring system, in which the heterocyclic ring system may be substituted by C 1-7 alkoxy, COOH, C 1-7 alkoxycarbonyl, NO 2 , C 1-7 alkyl, phenyl, phenyl-C 1-7 alkyl, or C 3-8 cycloalkylene; and R 4 is H, C 1-7 alkyl, aryl or aralkyl, in admixture with a solid or liquid pharmaceutically acceptable carrier or diluent, and if desired, other known chemotherapeutic agents, such as the sulphur drugs, the penicillins and/or the tetracyclines. The compositions are in forms suitable for oral, parenteral or topical administration.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70916668A | 1968-02-23 | 1968-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1191443A true GB1191443A (en) | 1970-05-13 |
Family
ID=24848748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB536969A Expired GB1191443A (en) | 1968-02-23 | 1969-01-31 | Quinoline Derivatives |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE1908542A1 (en) |
| FR (1) | FR2002436A1 (en) |
| GB (1) | GB1191443A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6653307B2 (en) | 2000-06-16 | 2003-11-25 | Pharmacia & Upjohn Company | 1-aryl-4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents |
| EP1081138B1 (en) * | 1999-08-30 | 2004-09-22 | Maruishi Pharmaceutical Co., Ltd. | 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3108069B1 (en) | 2020-03-12 | 2022-03-18 | Psa Automobiles Sa | VEHICLE WITH CONTROL OF BATTERY CHARGING BASED ON THE STATUS OF SENSORS OF A DIRECT CURRENT CHARGING PLUG |
-
1969
- 1969-01-31 GB GB536969A patent/GB1191443A/en not_active Expired
- 1969-02-05 FR FR6902513A patent/FR2002436A1/en active Granted
- 1969-02-20 DE DE19691908542 patent/DE1908542A1/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1081138B1 (en) * | 1999-08-30 | 2004-09-22 | Maruishi Pharmaceutical Co., Ltd. | 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds |
| US6653307B2 (en) | 2000-06-16 | 2003-11-25 | Pharmacia & Upjohn Company | 1-aryl-4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2002436B1 (en) | 1973-06-08 |
| DE1908542A1 (en) | 1969-09-18 |
| FR2002436A1 (en) | 1969-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |