GB1011288A - Benzoxazine-2:4-dione derivatives and a process of making same - Google Patents
Benzoxazine-2:4-dione derivatives and a process of making sameInfo
- Publication number
- GB1011288A GB1011288A GB3463662A GB3463662A GB1011288A GB 1011288 A GB1011288 A GB 1011288A GB 3463662 A GB3463662 A GB 3463662A GB 3463662 A GB3463662 A GB 3463662A GB 1011288 A GB1011288 A GB 1011288A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- group
- carbon atoms
- alkyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 alkyl radical Chemical class 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- QVNGETWOMZGVPD-UHFFFAOYSA-N 6-nitro-4a,5-dihydro-1,3-benzoxazine-2,4-dione Chemical compound [N+](=O)([O-])C1=CC=C2C(C(NC(O2)=O)=O)C1 QVNGETWOMZGVPD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000009153 reflex inhibition Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 125000004417 unsaturated alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B55/00—Azomethine dyes
- C09B55/002—Monoazomethine dyes
- C09B55/003—Monoazomethine dyes with the -C=N- group attached to an heteroring
- C09B55/004—Monoazomethine dyes with the -C=N- group attached to an heteroring with the -C=N- group between two heterorings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of formula <FORM:1011288/C2/1> wherein each of R1 and R2 represent a hydrogen atom, an alkyl radical having 1 to 6 carbon atoms, an esterified carboxyl group, a carbamoyl radial substituted by (a) an alkyl, haloalkyl, or unsaturated alkyl group, all containing up to 6 carbon atoms, or (b) an aryl or aralkyl radical, an aryl group, optionally halo-substituted, or a radical of formula <FORM:1011288/C2/2> wherein R3 and R4 are each a hydrogen atom, an alkyl radical having up to 6 carbon atoms or an aryl radical or R3 and R4 form, in combination with the nitrogen atom to which they are attached, a 5- or 6-membered ring which may be interrupted by an oxygen atom or an optionally alkylated nitrogen atom, present in the para-position in the case of a 6-membered ring, and R5 is a hydrogen atom, an alkyl group having up to 6 carbon atoms or an amino-group, or wherein R1 and R2 together form the radical =CH-R6 in which R6 is a heterocyclic radical, acid addition salts thereof, and their preparation by reduction of the compound of formula <FORM:1011288/C2/3> followed, if desired, by mono- or di-substitution of the amino-group formed. The compounds of the invention have analgesic, muscle-relaxant, reflex inhibition and temperature-decreasing activity. The 6-nitro-dihydro-1,3-benzoxazine-2,4-dione used as the starting material above is prepared by nitration.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1060161A CH401058A (en) | 1961-09-13 | 1961-09-13 | Process for the preparation of 6-amino-dihydro-1,3-benzoxazine-2,4-dione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1011288A true GB1011288A (en) | 1965-11-24 |
Family
ID=4364926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3463662A Expired GB1011288A (en) | 1961-09-13 | 1962-09-11 | Benzoxazine-2:4-dione derivatives and a process of making same |
Country Status (3)
| Country | Link |
|---|---|
| CH (1) | CH401058A (en) |
| GB (1) | GB1011288A (en) |
| NL (1) | NL283173A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114672020A (en) * | 2022-03-10 | 2022-06-28 | 天津科技大学 | A kind of preparation method of benzoxazine-based conjugated ladder polymer and its application in hydrogen sulfide detection |
-
0
- NL NL283173D patent/NL283173A/xx unknown
-
1961
- 1961-09-13 CH CH1060161A patent/CH401058A/en unknown
-
1962
- 1962-09-11 GB GB3463662A patent/GB1011288A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114672020A (en) * | 2022-03-10 | 2022-06-28 | 天津科技大学 | A kind of preparation method of benzoxazine-based conjugated ladder polymer and its application in hydrogen sulfide detection |
| CN114672020B (en) * | 2022-03-10 | 2023-10-20 | 天津科技大学 | Preparation method of benzoxazinyl conjugated trapezoid polymer and application of benzoxazinyl conjugated trapezoid polymer in hydrogen sulfide detection |
Also Published As
| Publication number | Publication date |
|---|---|
| CH401058A (en) | 1965-10-31 |
| NL283173A (en) |
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